Angiogenesis: mechanistic insights, neovascular diseases, and therapeutic prospects (Q40922411)

24 September 2017

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title

Angiogenesis: mechanistic insights, neovascular diseases, and therapeutic prospects (English)

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24 September 2017

E J Battegay

1

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24 September 2017

1 July 1995

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Journal of Molecular Medicine

24 September 2017

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24 September 2017

73

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24 September 2017

333-346

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24 September 2017

7

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https://scigraph.springernature.com/pub.10.1007/bf00192885

24 September 2017

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Inhibition of angiogenesis by tissue inhibitor of metalloproteinase

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Platelet-derived growth factor BB for the treatment of chronic pressure ulcers

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Angiogenesis in the female reproductive system

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Enhanced revascularization of the ischemic limb by angiogenic therapy

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Vascular endothelial growth factor messenger ribonucleic acid expression in the primate ovary

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Interleukin-8 as a macrophage-derived mediator of angiogenesis

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The type 1 repeats of thrombospondin 1 activate latent transforming growth factor-beta

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12 December 2020

Hypoxia induces glucose transporter expression in endothelial cells

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12 December 2020

Inhibitory action of transforming growth factor beta on endothelial cells

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12 December 2020

Immature rat ovaries become revascularized rapidly after autotransplantation and show a gonadotropin-dependent increase in angiogenic factor gene expression

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12 December 2020

Platelet-derived growth factor receptor-beta is induced during tumor development and upregulated during tumor progression in endothelial cells in human gliomas

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12 December 2020

Mechanism of action of angiostatic steroids: suppression of plasminogen activator activity via stimulation of plasminogen activator inhibitor synthesis

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12 December 2020

Angiogenic effects of low molecular weight heparin in patients with stable coronary artery disease: a pilot study

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12 December 2020

Hypothesis: vasa vasorum and neovascularization of human coronary arteries. A possible role in the pathophysiology of atherosclerosis

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12 December 2020

The role of PDGF-BB on the development of the collateral circulation after acute arterial occlusion.

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12 December 2020

Vascular endothelial growth factor--its role in retinal vascular proliferation

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12 December 2020

Platelet-Derived Growth Factor is AngiogenicIn Vivo

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12 December 2020

High affinity VEGF binding and developmental expression suggest Flk-1 as a major regulator of vasculogenesis and angiogenesis

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12 December 2020

Vitreous levels of the insulin-like growth factors I and II, and the insulin-like growth factor binding proteins 2 and 3, increase in neovascular eye disease. Studies in nondiabetic and diabetic subjects

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12 December 2020

Release of an inhibitor of angiogenesis upon induction of wild type p53 expression in glioblastoma cells

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12 December 2020

Angiogenesis, assessed by platelet/endothelial cell adhesion molecule antibodies, as indicator of node metastases and survival in breast cancer

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12 December 2020

Elevated levels of an angiogenic peptide, basic fibroblast growth factor, in the urine of patients with a wide spectrum of cancers

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12 December 2020

Rat brain capillary endothelial cells express functional PDGF B-type receptors

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12 December 2020

Media conditioned by smooth muscle cells cultured in a variety of hypoxic environments stimulates in vitro angiogenesis. A relationship to transforming growth factor-beta 1

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12 December 2020

Human microvascular endothelial cells express receptors for platelet-derived growth factor

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12 December 2020

Endothelial cell implantation and survival within experimental gliomas

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12 December 2020

Platelet-derived growth factor (BB homodimer), transforming growth factor-beta 1, and basic fibroblast growth factor in dermal wound healing. Neovessel and matrix formation and cessation of repair

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12 December 2020

Vascular cell adhesion molecule-1 is expressed in human coronary atherosclerotic plaques. Implications for the mode of progression of advanced coronary atherosclerosis

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12 December 2020

Growth factors and angiogenesis

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12 December 2020

Indirect angiogenic cytokines upregulate VEGF and bFGF gene expression in vascular smooth muscle cells, whereas hypoxia upregulates VEGF expression only

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12 December 2020

Extent of vascularization as a prognostic indicator in thin (< 0.76 mm) malignant melanomas

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12 December 2020

Endothelial control of vascular tone in large and small coronary arteries

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12 December 2020

Isolation of a human placenta cDNA coding for a protein related to the vascular permeability factor

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12 December 2020

Identification of haptoglobin as an angiogenic factor in sera from patients with systemic vasculitis

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12 December 2020

Interferon alfa-2a therapy for life-threatening hemangiomas of infancy

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12 December 2020

The extracellular glycoprotein SPARC interacts with platelet-derived growth factor (PDGF)-AB and -BB and inhibits the binding of PDGF to its receptors

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12 December 2020

Angiogenesis in cancer, vascular, rheumatoid and other disease

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12 December 2020

Pituitary follicular cells secrete an inhibitor of aortic endothelial cell growth: identification as leukemia inhibitory factor

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12 December 2020

In vitro angiogenic and proteolytic properties of bovine lymphatic endothelial cells

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12 December 2020

SPARC is a source of copper-binding peptides that stimulate angiogenesis

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12 December 2020

Transforming growth factor-beta activity is potentiated by heparin via dissociation of the transforming growth factor-beta/alpha 2-macroglobulin inactive complex

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12 December 2020

Control of angiogenesis in fibroblasts by p53 regulation of thrombospondin-1

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12 December 2020

Physiological consequences of loss of plasminogen activator gene function in mice

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12 December 2020

The diabetic rat as an impaired wound healing model: stimulatory effects of transforming growth factor-beta and basic fibroblast growth factor

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12 December 2020

Toward an understanding of angiogenesis: search and discovery

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12 December 2020

Expression of vascular endothelial growth factor during embryonic angiogenesis and endothelial cell differentiation

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12 December 2020

Modulation of extracellular matrix proteins by endothelial cells undergoing angiogenesis in vitro

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12 December 2020

Vascular permeability factor/endothelial growth factor (VPF/VEGF): accumulation and expression in human synovial fluids and rheumatoid synovial tissue

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12 December 2020

Hypoxic stimulation of vascular endothelial growth factor expression in vitro and in vivo.

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12 December 2020

A role for sialyl Lewis-X/A glycoconjugates in capillary morphogenesis

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12 December 2020

De novo generation of permanent neovascularized soft tissue appendages by platelet-derived growth factor

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12 December 2020

PDGF and TGF-alpha act synergistically to improve wound healing in the genetically diabetic mouse.

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12 December 2020

Increased expression of matrix metalloproteinases and matrix degrading activity in vulnerable regions of human atherosclerotic plaques

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12 December 2020

Vascular targeting and the inhibition of angiogenesis.

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12 December 2020

Thalidomide is an inhibitor of angiogenesis

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12 December 2020

Immunohistochemical study of intimal microvessels in coronary atherosclerosis

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12 December 2020

Expression of platelet-derived endothelial cell growth factor in Escherichia coli and confirmation of its thymidine phosphorylase activity

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12 December 2020

Platelet-derived growth factor (PDGF) in oncogenesis: development of a vascular connective tissue stroma in xenotransplanted human melanoma producing PDGF-BB

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12 December 2020

The collateral circulation of the heart

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12 December 2020

Tumour angiogenesis in prostatic carcinoma with and without bone marrow metastasis: A morphometric study

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12 December 2020

Angiogenesis can be stimulated or repressed in vivo by a change in GM3:GD3 ganglioside ratio

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12 December 2020

Erythropoietin receptor mRNA expression in human endothelial cells

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12 December 2020

Recent insights into coronary collateral circulation

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12 December 2020

Response of the FSaII fibrosarcoma to antiangiogenic modulators plus cytotoxic agents.

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12 December 2020

Synergy between basic fibroblast growth factor and HIV-1 Tat protein in induction of Kaposi's sarcoma

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12 December 2020

Growth factors in endothelial regeneration.

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12 December 2020

Correlation between angiogenesis and basic fibroblast growth factor expression in experimental brain infarct.

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12 December 2020

Integrin alpha v beta 3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels

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12 December 2020

Biphasic effect of transforming growth factor-beta 1 on in vitro angiogenesis

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12 December 2020

Thrombin mitogenic responses and protein phosphorylation are different in cultured human endothelial cells derived from large and microvessels

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12 December 2020

Identification of multiple active growth factors in basement membrane Matrigel suggests caution in interpretation of cellular activity related to extracellular matrix components

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12 December 2020

Suppression of collagen-induced arthritis using an angiogenesis inhibitor, AGM-1470, and a microtubule stabilizer, taxol

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12 December 2020

Reorganization of basement membrane matrices by cellular traction promotes the formation of cellular networks in vitro

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12 December 2020

Dose responsive effects of PDGF-BB, PDGF-AA, EGF, and bFGF on granulation tissue in a guinea pig partial thickness skin excision model

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12 December 2020

TGF-beta induces bimodal proliferation of connective tissue cells via complex control of an autocrine PDGF loop

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12 December 2020

Angiogenesis during human extraembryonic development involves the spatiotemporal control of PDGF ligand and receptor gene expression

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12 December 2020

Angiostatin: a novel angiogenesis inhibitor that mediates the suppression of metastases by a Lewis lung carcinoma

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12 December 2020

Embryonic angiogenesis factors

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12 December 2020

Release of transforming growth factor-beta 1 from the pericellular matrix of cultured fibroblasts and fibrosarcoma cells by plasmin and thrombin

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12 December 2020

Inhibition of endothelial cell movement by pericytes and smooth muscle cells: activation of a latent transforming growth factor-beta 1-like molecule by plasmin during co-culture

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12 December 2020

Production of angiogenic activity by human monocytes requires an L-arginine/nitric oxide-synthase-dependent effector mechanism

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12 December 2020

The 16-kilodalton N-terminal fragment of human prolactin is a potent inhibitor of angiogenesis

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12 December 2020

Oxygen tension regulates the expression of the platelet-derived growth factor-B chain gene in human endothelial cells

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12 December 2020

Scatter factor induces blood vessel formation in vivo

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12 December 2020

Mechanism of activation of latent recombinant transforming growth factor beta 1 by plasmin

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12 December 2020

Inhibition of basement membrane biosynthesis prevents angiogenesis

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12 December 2020

Patterns of expression of vascular endothelial growth factor (VEGF) and VEGF receptors in mice suggest a role in hormonally regulated angiogenesis

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12 December 2020

Cancer metastasis and angiogenesis: An imbalance of positive and negative regulation

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12 December 2020

A cartilage-derived inhibitor of neovascularization and metalloproteinases.

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12 December 2020

An activated form of transforming growth factor beta is produced by cocultures of endothelial cells and pericytes

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12 December 2020

Basic fibroblast growth factor improves myocardial function in chronically ischemic porcine hearts

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12 December 2020

Angiogenic activity of enzymes.

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12 December 2020

Angiogenic growth factors

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12 December 2020

Tumor angiogenesis: review of current applications in tumor prognostication

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12 December 2020

Characterization of monocyte adherence to human macrovascular and microvascular endothelial cells

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12 December 2020

Phenotypic diversity in cultured cerebral microvascular endothelial cells

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12 December 2020

Insulin-like growth factor I acts as an angiogenic agent in rabbit cornea and retina: comparative studies with basic fibroblast growth factor

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12 December 2020

Interaction of the allogeneic state and hypercholesterolemia in arterial lesion formation in experimental cardiac allografts

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12 December 2020

Expression of decorin by sprouting bovine aortic endothelial cells exhibiting angiogenesis in vitro

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12 December 2020

Molecular biologic concepts of coronary anastomoses

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12 December 2020

Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis

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12 December 2020

Up-regulation of vascular endothelial growth factor and its cognate receptors in a rat glioma model of tumor angiogenesis.

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12 December 2020

The effects of platelet-derived growth factor in cultured microvessel endothelial cells

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12 December 2020

Expression of the vascular permeability factor/vascular endothelial growth factor gene in central nervous system neoplasms.

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12 December 2020

Differential expression of extracellular proteins is correlated with angiogenesis in vitro

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12 December 2020

Therapeutic angiogenesis. A single intraarterial bolus of vascular endothelial growth factor augments revascularization in a rabbit ischemic hind limb model

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12 December 2020

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12 December 2020

Inhibition of IGF-I and b-FGF stimulated growth of human retinal endothelial cells by the somatostatin analogue, octreotide: a potential treatment for ocular neovascularization

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12 December 2020

Peptides derived from two separate domains of the matrix protein thrombospondin-1 have anti-angiogenic activity

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12 December 2020

1992 Mack Forster Award Lecture. Review. Regulation of angiogenesis in vitro

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12 December 2020

Thrombospondin binds and activates the small and large forms of latent transforming growth factor-beta in a chemically defined system

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12 December 2020

Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo

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12 December 2020

Glioblastoma growth inhibited in vivo by a dominant-negative Flk-1 mutant

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12 December 2020

Hepatocyte growth factor is a potent angiogenic factor which stimulates endothelial cell motility and growth

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12 December 2020

Angiogenesis and colonization in the tumor metastatic process: basic and applied advances

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12 December 2020

Clinical prognostic significance of tumour angiogenesis

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12 December 2020

Angiogenic macrophages produce the angiogenic inhibitor thrombospondin 1.

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12 December 2020

Tissue localization of beta receptors for platelet-derived growth factor and platelet-derived growth factor B chain during wound repair in humans

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12 December 2020

The endogenous oestrogen metabolite 2-methoxyoestradiol inhibits angiogenesis and suppresses tumour growth

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12 December 2020

Antigenic heterogeneity of vascular endothelium

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12 December 2020

Treatment of childhood angiomatous diseases with recombinant interferon alfa-2a

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12 December 2020

Vascular endothelial growth factor is a potential tumour angiogenesis factor in human gliomas in vivo.

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12 December 2020

Angiogenesis and endothelial cell function.

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12 December 2020

Modulation of platelet-derived growth factor receptor expression in microvascular endothelial cells during in vitro angiogenesis

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12 December 2020

The prognostic significance of tumor vascularity in intermediate-thickness (0.76-4.0 mm thick) skin melanoma. A quantitative histologic study

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12 December 2020

Salvage of infarcted myocardium by angiogenic action of basic fibroblast growth factor

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12 December 2020

Functional significance of collaterals during ameroid-induced coronary stenosis in conscious dogs. Interrelationships among regional shortening, regional flow and grade of coronary stenosis

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12 December 2020

Inhibition of endothelial regeneration by type-beta transforming growth factor from platelets

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12 December 2020

Migration and proliferation of endothelial cells in preformed and newly formed blood vessels during tumor angiogenesis

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12 December 2020

Latent transforming growth factor-beta 1 associates to fibroblast extracellular matrix via latent TGF-beta binding protein

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12 December 2020

Vascular endothelial growth factor (VEGF) induces plasminogen activators and plasminogen activator inhibitor-1 in microvascular endothelial cells

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12 December 2020

Inhibition of Angiogenesis by Recombinant Human Platelet Factor-4 and Related Peptides

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12 December 2020

Angiogenic processes in the pathogenesis of human coronary atherosclerosis.

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12 December 2020

Extracellular matrix and cell shape: potential control points for inhibition of angiogenesis

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12 December 2020

Tumor necrosis factor alpha-induced angiogenesis depends on in situ platelet-activating factor biosynthesis.

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12 December 2020

Inhibition of interleukin 8 attenuates angiogenesis in bronchogenic carcinoma

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12 December 2020

Suppression of solid tumor growth by immunoneutralizing monoclonal antibody against human basic fibroblast growth factor

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12 December 2020

Vascular endothelial growth factor induces interstitial collagenase expression in human endothelial cells

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12 December 2020

Tumor microvessel density, p53 expression, tumor size, and peritumoral lymphatic vessel invasion are relevant prognostic markers in node-negative breast carcinoma.

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12 December 2020

Block of AIDS-Kaposi's sarcoma (KS) cell growth, angiogenesis, and lesion formation in nude mice by antisense oligonucleotide targeting basic fibroblast growth factor. A novel strategy for the therapy of KS.

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12 December 2020

Interleukin-8. A corneal factor that induces neovascularization

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12 December 2020

Placenta growth factor. Potentiation of vascular endothelial growth factor bioactivity, in vitro and in vivo, and high affinity binding to Flt-1 but not to Flk-1/KDR

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12 December 2020

Isolation and characterization of vasoformative endothelial cells from the rat aorta

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12 December 2020

Stable expression of human platelet-derived growth factor B chain by bovine aortic endothelial cells. Matrix association and selective proteolytic cleavage by thrombin

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12 December 2020

PDGF-BB modulates endothelial proliferation and angiogenesis in vitro via PDGF beta-receptors

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12 December 2020

Inhibition of endothelial cell proliferation by platelet factor-4 involves a unique action on S phase progression

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12 December 2020

Downregulation of endothelial cell thrombospondin 1 enhances in vitro angiogenesis

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12 December 2020

Vascular endothelial growth factor. A cytokine modulating endothelial function in rheumatoid arthritis

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12 December 2020

Fibrogenic cytokines and connective tissue production.

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12 December 2020

Growth factors are released by mechanically wounded endothelial cells

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12 December 2020

Platelet-derived growth factor and its receptors in human glioma tissue: expression of messenger RNA and protein suggests the presence of autocrine and paracrine loops

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12 December 2020

Three novel synthetic retinoids, Re 80, Am 580 and Am 80, all exhibit anti-angiogenic activity in vivo

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12 December 2020

Stimulation and inhibition of angiogenesis by placental proliferin and proliferin-related protein

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12 December 2020

The interaction of HGF-SF with other cytokines in tumor invasion and angiogenesis

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12 December 2020

Increased vascular endothelial growth factor levels in the vitreous of eyes with proliferative diabetic retinopathy

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12 December 2020

AIDS-associated Kaposi's sarcoma cells in culture express vascular endothelial growth factor

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12 December 2020

Vascular endothelial growth factor/vascular permeability factor is temporally and spatially correlated with ocular angiogenesis in a primate model.

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12 December 2020

Tumor angiogenesis and metastasis--correlation in invasive breast carcinoma

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12 December 2020

Regulation of the activity of a new inhibitor of angiogenesis by a cancer suppressor gene.

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12 December 2020

Coronary collateral recruitment: functional significance and relation to rate of vessel closure

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12 December 2020

Pentosan inhibits angiogenesis in vitro and suppresses prostate tumor growth in vivo

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12 December 2020

Endothelial cells exhibiting angiogenesis in vitro proliferate in response to TGF-beta 1

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12 December 2020

Intracoronary injection of basic fibroblast growth factor enhances angiogenesis in infarcted swine myocardium

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12 December 2020

Identifiers

DOI

10.1007/BF00192885

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24 September 2017

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PubMed ID

8520966