Retinal ligand mobility explains internal hydration and reconciles active rhodopsin structures (Q30712788)

13 October 2017

Retinal ligand mobility explains internal hydration and reconciles active rhodopsin structures (English)

1 reference

13 October 2017

1

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10 June 2020

Alan Grossfield

7

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10 June 2020

author name string

Blake Mertz

2

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10 June 2020

Karina Martínez-Mayorga

3

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10 June 2020

Tod D Romo

4

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10 June 2020

Michael C Pitman

5

1 reference

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10 June 2020

Scott E Feller

6

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10 June 2020

Michael F Brown

8

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10 June 2020

language of work or name

English

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publication date

8 January 2014

1 reference

13 October 2017

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10 June 2020

volume

53

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10 June 2020

issue

2

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10 June 2020

page(s)

376-385

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Rhodopsin Absorption from First Principles: Bypassing Common Pitfalls

10 June 2020

cites work

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20 June 2018

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Retinal conformation governs pKa of protonated Schiff base in rhodopsin activation

20 June 2018

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A new era of GPCR structural and chemical biology

20 June 2018

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Structural transitions of transmembrane helix 6 in the formation of metarhodopsin I.

20 June 2018

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Stabilized G protein binding site in the structure of constitutively active metarhodopsin-II

20 June 2018

1 reference

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Steric and electronic influences on the torsional energy landscape of retinal

20 June 2018

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Solid-state 2H NMR relaxation illuminates functional dynamics of retinal cofactor in membrane activation of rhodopsin

20 June 2018

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Role of bulk water in hydrolysis of the rhodopsin chromophore

20 June 2018

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Crystal structure of metarhodopsin II

20 June 2018

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The structural basis of agonist-induced activation in constitutively active rhodopsin

20 June 2018

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Retinal dynamics underlie its switch from inverse agonist to agonist during rhodopsin activation

20 June 2018

1 reference

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Conserved water-mediated hydrogen bond network between TM-I, -II, -VI, and -VII in 7TM receptor activation

20 June 2018

1 reference

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LOOS: an extensible platform for the structural analysis of simulations.

20 June 2018

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Normal mode analysis of biomolecular structures: functional mechanisms of membrane proteins

20 June 2018

1 reference

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Structural waters define a functional channel mediating activation of the GPCR, rhodopsin.

20 June 2018

1 reference

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The structure and function of G-protein-coupled receptors

20 June 2018

1 reference

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Conserved waters mediate structural and functional activation of family A (rhodopsin-like) G protein-coupled receptors

20 June 2018

1 reference

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Ligand binding and micro-switches in 7TM receptor structures

20 June 2018

1 reference

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Location of the retinal chromophore in the activated state of rhodopsin*.

20 June 2018

1 reference

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Photochemical reaction dynamics of the primary event of vision studied by means of a hybrid molecular simulation

20 June 2018

1 reference

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Crystal structure of opsin in its G-protein-interacting conformation

20 June 2018

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Internal hydration increases during activation of the G-protein-coupled receptor rhodopsin

20 June 2018

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Crystal structure of the ligand-free G-protein-coupled receptor opsin

20 June 2018

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High-resolution distance mapping in rhodopsin reveals the pattern of helix movement due to activation

20 June 2018

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Dynamic structure of retinylidene ligand of rhodopsin probed by molecular simulations

20 June 2018

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Structural analysis and dynamics of retinal chromophore in dark and meta I states of rhodopsin from 2H NMR of aligned membranes

20 June 2018

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How many drug targets are there?

20 June 2018

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Local peptide movement in the photoreaction intermediate of rhodopsin

20 June 2018

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Crystallographic analysis of primary visual photochemistry

20 June 2018

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A role for direct interactions in the modulation of rhodopsin by omega-3 polyunsaturated lipids.

20 June 2018

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Location of Trp265 in metarhodopsin II: implications for the activation mechanism of the visual receptor rhodopsin

20 June 2018

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Molecular mechanism of 7TM receptor activation--a global toggle switch model

20 June 2018

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Electron crystallography reveals the structure of metarhodopsin I.

20 June 2018

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Historical review: a brief history and personal retrospective of seven-transmembrane receptors

20 June 2018

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Coupling of retinal isomerization to the activation of rhodopsin

20 June 2018

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Membrane model for the G-protein-coupled receptor rhodopsin: hydrophobic interface and dynamical structure

20 June 2018

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The G-protein-coupled receptors in the human genome form five main families. Phylogenetic analysis, paralogon groups, and fingerprints

20 June 2018

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Rhodopsin structure, dynamics, and activation: a perspective from crystallography, site-directed spin labeling, sulfhydryl reactivity, and disulfide cross-linking

20 June 2018

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Beta2 adrenergic receptor activation. Modulation of the proline kink in transmembrane 6 by a rotamer toggle switch

20 June 2018

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Activation, deactivation, and adaptation in vertebrate photoreceptor cells

20 June 2018

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Activation of rhodopsin: new insights from structural and biochemical studies

20 June 2018

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Orphan G-protein-coupled receptors and natural ligand discovery

20 June 2018

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Crystal structure of rhodopsin: A G protein-coupled receptor

20 June 2018

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The good taste of genomics

20 June 2018

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Absorption spectroscopy in studies of visual pigments: spectral and kinetic characterization of intermediates

20 June 2018

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Seven-transmembrane proteins as odorant and chemosensory receptors

20 June 2018

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Energy uptake in the first step of visual excitation

20 June 2018

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Light activation of rhodopsin: insights from molecular dynamics simulations guided by solid-state NMR distance restraints

20 June 2018

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Modulating rhodopsin receptor activation by altering the pKa of the retinal Schiff base.

25 November 2018

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The role of Glu181 in the photoactivation of rhodopsin

25 November 2018

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The retinal conformation and its environment in rhodopsin in light of a new 2.2 A crystal structure

25 November 2018

1 reference

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Retinal counterion switch mechanism in vision evaluated by molecular simulations

25 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24328554

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Convergence of molecular dynamics simulations of membrane proteins

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24328554

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1021/BI4013947

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24328554%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24328554%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

PubMed publication ID

24328554

1 reference