Magnesium and phosphate ions enable NAD binding to methylenetetrahydrofolate dehydrogenase-methenyltetrahydrofolate cyclohydrolase (Q30668561)

26 June 2017

Magnesium and phosphate ions enable NAD binding to methylenetetrahydrofolate dehydrogenase-methenyltetrahydrofolate cyclohydrolase (English)

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Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase

26 June 2017

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GOA release 2020-03-11

phosphate ion binding

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GOA release 2020-03-11

Albert M Berghuis

3

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author name string

Karen E Christensen

series ordinal

1

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26 June 2017

I Ahmad Mirza

series ordinal

2

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26 June 2017

Robert E Mackenzie

series ordinal

4

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26 June 2017

language of work or name

English

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publication date

11 August 2005

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Journal of Biological Chemistry

26 June 2017

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26 June 2017

280

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26 June 2017

40

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26 June 2017

34316-34323

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Disruption of the mthfd1 gene reveals a monofunctional 10-formyltetrahydrofolate synthetase in mammalian mitochondria

26 June 2017

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https://api.crossref.org/works/10.1074%2FJBC.M505210200

Mammalian fibroblasts lacking mitochondrial NAD+-dependent methylenetetrahydrofolate dehydrogenase-cyclohydrolase are glycine auxotrophs

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505210200

NAD-dependent methylenetetrahydrofolate dehydrogenase-methenyltetrahydrofolate cyclohydrolase is the mammalian homolog of the mitochondrial enzyme encoded by the yeast MIS1 gene

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M505210200

Mammalian mitochondrial methylenetetrahydrofolate dehydrogenase-cyclohydrolase derived from a trifunctional methylenetetrahydrofolate dehydrogenase-cyclohydrolase-synthetase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505210200

Mitochondrial NAD-dependent methylenetetrahydrofolate dehydrogenase-methenyltetrahydrofolate cyclohydrolase is essential for embryonic development

21 January 2018

1 reference

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The 3-D structure of a folate-dependent dehydrogenase/cyclohydrolase bifunctional enzyme at 1.5 A resolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505210200

Structures of three inhibitor complexes provide insight into the reaction mechanism of the human methylenetetrahydrofolate dehydrogenase/cyclohydrolase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505210200

The crystal structure of a bacterial, bifunctional 5, 10 methylene-tetrahydrofolate dehydrogenase/cyclohydrolase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505210200

The X-ray structure of the NAD-dependent 5,10-methylenetetrahydrofolate dehydrogenase fromSaccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505210200

Formiminotransferase-cyclodeaminase from procine liver. Purification and physical properties of the enzyme complex

21 January 2018

1 reference

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CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

21 January 2018

1 reference

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Use of non-crystallographic symmetry in protein structure refinement

21 January 2018

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Improved methods for building protein models in electron density maps and the location of errors in these models

21 January 2018

1 reference

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Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

21 January 2018

1 reference

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Residues involved in the mechanism of the bifunctional methylenetetrahydrofolate dehydrogenase-cyclohydrolase: the roles of glutamine 100 and aspartate 125.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M505210200

PROCHECK: a program to check the stereochemical quality of protein structures

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M505210200

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

21 January 2018

1 reference

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Methenyltetrahydrofolate cyclohydrolase is rate limiting for the enzymatic conversion of 10-formyltetrahydrofolate to 5,10-methylenetetrahydrofolate in bifunctional dehydrogenase-cyclohydrolase enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505210200

Principles governing Mg, Ca, and Zn binding and selectivity in proteins.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M505210200

The crystal structure of methylglyoxal synthase from Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505210200

High specificity of a phosphate transport protein determined by hydrogen bonds

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505210200

Crystal structure of bovine heart phosphotyrosyl phosphatase at 2.2-A resolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505210200

Metal-binding sites in proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505210200

Redesign of the coenzyme specificity of a dehydrogenase by protein engineering

21 January 2018

1 reference

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Crystal structure of an enzyme displaying both inositol-polyphosphate-1-phosphatase and 3'-phosphoadenosine-5'-phosphate phosphatase activities: a novel target of lithium therapy

21 January 2018

1 reference

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NADP-dependent enzymes. I: Conserved stereochemistry of cofactor binding

21 January 2018

1 reference

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Modification of the nucleotide cofactor-binding site of cytochrome P-450 reductase to enhance turnover with NADH in Vivo

21 January 2018

1 reference

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Involvement of the pyrophosphate and the 2'-phosphate binding regions of ferredoxin-NADP+ reductase in coenzyme specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505210200

Channeling efficiency in the bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase domain: the effects of site-directed mutagenesis of NADP binding residues

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505210200

Methylenetetrahydrofolate dehydrogenase-cyclohydrolase from Photobacterium phosphoreum shares properties with a mammalian mitochondrial homologue

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505210200

21 January 2018

Identifiers

DOI

10.1074/JBC.M505210200

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26 June 2017

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