VEGF/neuropilin-2 regulation of Bmi-1 and consequent repression of IGF-IR define a novel mechanism of aggressive prostate cancer (Q30595149)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22777769%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

title

VEGF/neuropilin-2 regulation of Bmi-1 and consequent repression of IGF-IR define a novel mechanism of aggressive prostate cancer (English)

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7 February 2020

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2

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12

Robert L Vessella

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7 February 2020

13

Roger J Davis

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7 February 2020

author name string

Hira Lal Goel

1

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7 February 2020

Bryan Pursell

3

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7 February 2020

Irwin Leav

4

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7 February 2020

Stephen Lyle

5

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7 February 2020

Hualin Simon Xi

6

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7 February 2020

Chung-Cheng Hsieh

7

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7 February 2020

Helty Adisetiyo

8

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7 February 2020

Pradip Roy-Burman

9

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7 February 2020

Ilsa M Coleman

10

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7 February 2020

Peter S Nelson

11

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Stephen R Plymate

14

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Arthur M Mercurio

15

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7 February 2020

publication date

9 July 2012

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7 February 2020

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7 February 2020

volume

2

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7 February 2020

page(s)

906-921

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7 February 2020

issue

10

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Neuropilin-2 regulates α6β1 integrin in the formation of focal adhesions and signaling

7 February 2020

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Expression of the IGF axis is decreased in local prostate cancer but enhanced after benign prostate epithelial differentiation and TGF-β treatment

14 July 2018

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14 July 2018

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Neuropilin-2 promotes branching morphogenesis in the mouse mammary gland

14 July 2018

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Bmi-1 is a crucial regulator of prostate stem cell self-renewal and malignant transformation

14 July 2018

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A mutated soluble neuropilin-2 B domain antagonizes vascular endothelial growth factor bioactivity and inhibits tumor progression

14 July 2018

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Castration resistance in human prostate cancer is conferred by a frequently occurring androgen receptor splice variant

14 July 2018

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Integrative genomic profiling of human prostate cancer

14 July 2018

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ERbeta impedes prostate cancer EMT by destabilizing HIF-1alpha and inhibiting VEGF-mediated snail nuclear localization: implications for Gleason grading

14 July 2018

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Direct transcriptional regulation of neuropilin-2 by COUP-TFII modulates multiple steps in murine lymphatic vessel development

14 July 2018

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Autocrine VEGF signaling synergizes with EGFR in tumor cells to promote epithelial cancer development

14 July 2018

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Differential requirement for focal adhesion kinase signaling in cancer progression in the transgenic adenocarcinoma of mouse prostate model

14 July 2018

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Vascular endothelial growth factor-C protects prostate cancer cells from oxidative stress by the activation of mammalian target of rapamycin complex-2 and AKT-1.

14 July 2018

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Emerging role of insulin-like growth factor receptor inhibitors in oncology: early clinical trial results and future directions

14 July 2018

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Regulation of beta 4-integrin expression by epigenetic modifications in the mammary gland and during the epithelial-to-mesenchymal transition

14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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Blocking neuropilin-2 function inhibits tumor cell metastasis

14 July 2018

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Identification of the JNK signaling pathway as a functional target of the tumor suppressor PTEN.

14 July 2018

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Blocking neuropilin-1 function has an additive effect with anti-VEGF to inhibit tumor growth

14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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Loss of PTEN expression in paraffin-embedded primary prostate cancer correlates with high Gleason score and advanced stage.

14 July 2018

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Selection of highly metastatic variants of different human prostatic carcinomas using orthotopic implantation in nude mice

14 July 2018

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Neuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor for vascular endothelial growth factor

14 July 2018

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The effect on the insulin-like growth factor system in human prostate epithelial cells of immortalization and transformation by simian virus-40 T antigen

14 July 2018

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Simian virus 40 large tumor antigen is unable to transform mouse embryonic fibroblasts lacking type 1 insulin-like growth factor receptor

14 July 2018

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Therapeutic targeting of neuropilin-2 on colorectal carcinoma cells implanted in the murine liver

14 July 2018

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Neuropilin-1 and neuropilin-2 act as coreceptors, potentiating proangiogenic activity.

26 November 2018

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Expression of the VEGF-receptor Flt-1 in benign, premalignant and malignant prostate tissues.

26 November 2018

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Soluble receptor activator of nuclear factor kappaB Fc diminishes prostate cancer progression in bone

26 November 2018

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12 December 2020

Growth and differentiation signals by the insulin-like growth factor 1 receptor in hemopoietic cells are mediated through different pathways

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12 December 2020

The JNK signal transduction pathway

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12 December 2020

A vascular niche and a VEGF–Nrp1 loop regulate the initiation and stemness of skin tumours

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12 December 2020

10.1158/2159-8290.CD-12-0085

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22777769%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

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7 February 2020

1 reference