Neuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor for vascular endothelial growth factor (Q24321564)

GOA release 2020-03-11

author name string

S Soker

1

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S Takashima

2

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H Q Miao

3

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G Neufeld

4

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M Klagsbrun

Neurotrophic factors and their receptors

5

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language of work or name

English

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publication date

20 March 1998

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published in

Cell

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volume

92

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page(s)

735-45

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issue

6

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cites work

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Neuropilin-2, a novel member of the neuropilin family, is a high affinity receptor for the semaphorins Sema E and Sema IV but not Sema III

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Activation of HER4 by heparin-binding EGF-like growth factor stimulates chemotaxis but not proliferation

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Vascular endothelial growth factor induces the disorganization of actin stress fibers accompanied by protein tyrosine phosphorylation and morphological change in Balb/C3T3 cells

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Secreted chick semaphorins bind recombinant neuropilin with similar affinities but bind different subsets of neurons in situ.

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Vascular endothelial growth factor (VEGF) and VEGF receptor 2 (flk-1) are expressed during vasculogenesis and vascular differentiation in the quail embryo.

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Growth-associated expression of a membrane protein, neuropilin, in Xenopus optic nerve fibers.

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Expression cloning of a receptor for human granulocyte-macrophage colony-stimulating factor

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Neuropilin is a receptor for the axonal chemorepellent Semaphorin III

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A novel vascular endothelial growth factor, VEGF-C, is a ligand for the Flt4 (VEGFR-3) and KDR (VEGFR-2) receptor tyrosine kinases

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Developmentally regulated expression of a cell surface protein, neuropilin, in the mouse nervous system.

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Neuropilin-semaphorin III/D-mediated chemorepulsive signals play a crucial role in peripheral nerve projection in mice.

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The semaphorin genes encode a family of transmembrane and secreted growth cone guidance molecules

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Neuropilin is a semaphorin III receptor

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Vascular endothelial growth factor is a secreted angiogenic mitogen

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Vasculotropin/vascular endothelial growth factor induces differentiation in cultured osteoblasts

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High affinity VEGF binding and developmental expression suggest Flk-1 as a major regulator of vasculogenesis and angiogenesis

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Expression of a cell adhesion molecule, neuropilin, in the developing chick nervous system

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Identification of the KDR tyrosine kinase as a receptor for vascular endothelial cell growth factor

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Vascular endothelial growth factor: a new member of the platelet-derived growth factor gene family

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Differential endothelial migration and proliferation to basic fibroblast growth factor and vascular endothelial growth factor

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