The formin FHOD1 and the small GTPase Rac1 promote vaccinia virus actin-based motility (Q30547698)

18 August 2017

The formin FHOD1 and the small GTPase Rac1 promote vaccinia virus actin-based motility (English)

1 reference

18 August 2017

vaccinia virus

1 reference

Diego E Alvarez

1

1 reference

PMCID

3787377

18 August 2017

Hervé Agaisse

series ordinal

2

1 reference

PMCID

3787377

18 August 2017

language of work or name

English

0 references

publication date

23 September 2013

1 reference

18 August 2017

Journal of Cell Biology

1 reference

18 August 2017

202

1 reference

18 August 2017

7

1 reference

18 August 2017

1075-1090

1 reference

FMNL2 drives actin-based protrusion and migration downstream of Cdc42.

18 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787377

Casein kinase 2 regulates vaccinia virus actin tail formation

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787377

RNAi screen reveals host cell kinases specifically involved in Listeria monocytogenes spread from cell to cell

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787377

Rickettsia Sca2 is a bacterial formin-like mediator of actin-based motility

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787377

Defining a core set of actin cytoskeletal proteins critical for actin-based motility of Rickettsia

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787377

Disruption of the Rickettsia rickettsii Sca2 autotransporter inhibits actin-based motility

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787377

Requirement for formin-induced actin polymerization during spread of Shigella flexneri

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787377

Regulatory mimicry in Listeria monocytogenes actin-based motility.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787377

The rate of N-WASP exchange limits the extent of ARP2/3-complex-dependent actin-based motility

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787377

Vaccinia virus morphogenesis and dissemination

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787377

The human formin FHOD1 contains a bipartite structure of FH3 and GTPase-binding domains required for activation

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787377

The Diaphanous-related Formin FHOD1 associates with ROCK1 and promotes Src-dependent plasma membrane blebbing

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787377

Structure of the autoinhibitory switch in formin mDia1.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787377

Abl collaborates with Src family kinases to stimulate actin-based motility of vaccinia virus

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787377

Biochemical characterization of the diaphanous autoregulatory interaction in the formin homology protein FHOD1

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787377

Oligomerization of the diaphanous-related formin FHOD1 requires a coiled-coil motif critical for its cytoskeletal and transcriptional activities

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787377

SRC mediates a switch from microtubule- to actin-based motility of vaccinia virus

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787377

Cdc42, Rac1, and Rac2 display distinct patterns of activation during phagocytosis.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787377

Identification of FHOD1-binding proteins and mechanisms of FHOD1-regulated actin dynamics

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787377

The mouse formin, FRLalpha, slows actin filament barbed end elongation, competes with capping protein, accelerates polymerization from monomers, and severs filaments

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787377

A conserved mechanism for Bni1- and mDia1-induced actin assembly and dual regulation of Bni1 by Bud6 and profilin

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787377

Mutations in the vaccinia virus A33R and B5R envelope proteins that enhance release of extracellular virions and eliminate formation of actin-containing microvilli without preventing tyrosine phosphorylation of the A36R protein

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787377

Fhos, a mammalian formin, directly binds to F-actin via a region N-terminal to the FH1 domain and forms a homotypic complex via the FH2 domain to promote actin fiber formation

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787377

The mouse Formin mDia1 is a potent actin nucleation factor regulated by autoinhibition

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787377

The formins: active scaffolds that remodel the cytoskeleton

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787377

Activation of the Rac-binding partner FHOD1 induces actin stress fibers via a ROCK-dependent mechanism

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787377

Cellular motility driven by assembly and disassembly of actin filaments

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787377

The formation and function of extracellular enveloped vaccinia virus

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787377

Role of formins in actin assembly: nucleation and barbed-end association

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787377

Grb2 and Nck act cooperatively to promote actin-based motility of vaccinia virus

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787377

Cdc42 facilitates invasion but not the actin-based motility of Shigella

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787377

The vaccinia virus F12L protein is associated with intracellular enveloped virus particles and is required for their egress to the cell surface

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787377

In vivo rho GTPase-activating protein activity of Pseudomonas aeruginosa cytotoxin ExoS

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787377

Vaccinia virus intracellular movement is associated with microtubules and independent of actin tails

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787377

The formin/diaphanous-related protein, FHOS, interacts with Rac1 and activates transcription from the serum response element

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787377

Listeria protein ActA mimics WASp family proteins: it activates filament barbed end branching by Arp2/3 complex

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787377

Vaccinia virus utilizes microtubules for movement to the cell surface.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787377

Visualization of intracellular movement of vaccinia virus virions containing a green fluorescent protein-B5R membrane protein chimera

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787377

A novel neural Wiskott-Aldrich syndrome protein (N-WASP) binding protein, WISH, induces Arp2/3 complex activation independent of Cdc42

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787377

Identification of a carboxyl-terminal diaphanous-related formin homology protein autoregulatory domain

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787377

Cooperation between mDia1 and ROCK in Rho-induced actin reorganization

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787377

Tools of the trade: use of dominant-inhibitory mutants of Ras-family GTPases

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787377

A visual screen of a GFP-fusion library identifies a new type of nuclear envelope membrane protein

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787377

Interactions between vaccinia virus IEV membrane proteins and their roles in IEV assembly and actin tail formation

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787377

Interaction of human Arp2/3 complex and the Listeria monocytogenes ActA protein in actin filament nucleation

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787377

Roles of vaccinia virus EEV-specific proteins in intracellular actin tail formation and low pH-induced cell-cell fusion

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787377

Role for the vaccinia virus A36R outer envelope protein in the formation of virus-tipped actin-containing microvilli and cell-to-cell virus spread

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787377

Identification of two regions in the N-terminal domain of ActA involved in the actin comet tail formation by Listeria monocytogenes.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787377

A role for Rho in Ras transformation

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787377

Progeny vaccinia and human cytomegalovirus particles utilize early endosomal cisternae for their envelopes.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787377

Deletion of the vaccinia virus B5R gene encoding a 42-kilodalton membrane glycoprotein inhibits extracellular virus envelope formation and dissemination.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787377

Assembly of vaccinia virus: the second wrapping cisterna is derived from the trans Golgi network.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787377

Vaccinia virus gene A36R encodes a M(r) 43-50 K protein on the surface of extracellular enveloped virus

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787377

Regulation of surface presentation of IcsA, a Shigella protein essential to intracellular movement and spread, is growth phase dependent.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787377

Cdc42 and PAK-mediated signaling leads to Jun kinase and p38 mitogen-activated protein kinase activation

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787377

Golgi-derived membranes that contain an acylated viral polypeptide are used for vaccinia virus envelopment

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787377

Identification of icsA, a plasmid locus of Shigella flexneri that governs bacterial intra- and intercellular spread through interaction with F-actin

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787377

The small GTP-binding protein rac regulates growth factor-induced membrane ruffling

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787377

A constitutively expressed vaccinia gene encodes a 42-kDa glycoprotein related to complement control factors that forms part of the extracellular virus envelope

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787377

Characterization of a vaccinia virus-encoded 42-kilodalton class I membrane glycoprotein component of the extracellular virus envelope

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787377

F11L-mediated inhibition of RhoA-mDia signaling stimulates microtubule dynamics during vaccinia virus infection.

14 July 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201303055

Actin-based motility of vaccinia virus mimics receptor tyrosine kinase signalling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201303055

Src regulates the activity of the mammalian formin protein FHOD1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201303055

Control of the assembly of ATP- and ADP-actin by formins and profilin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201303055

The regulation of mDia1 by autoinhibition and its release by Rho*GTP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201303055

Formin proteins: purification and measurement of effects on actin assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201303055

Structural basis of actin filament nucleation and processive capping by a formin homology 2 domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201303055

Kinesin-dependent movement on microtubules precedes actin-based motility of vaccinia virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201303055

Formin is a processive motor that requires profilin to accelerate actin assembly and associated ATP hydrolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201303055

Three regions within ActA promote Arp2/3 complex-mediated actin nucleation and Listeria monocytogenes motility

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201303055

The vaccinia virus A36R protein is a type Ib membrane protein present on intracellular but not extracellular enveloped virus particles

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201303055

FHOD1 is a combined actin filament capping and bundling factor that selectively associates with actin arcs and stress fibers

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201303055

Clathrin Potentiates Vaccinia-Induced Actin Polymerization to Facilitate Viral Spread

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201303055

Mechanistic Differences in Actin Bundling Activity of Two Mammalian Formins, FRL1 and mDia2

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201303055

SnapShot: actin regulators I.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787377

Neural Wiskott-Aldrich syndrome protein (N-WASP) is the specific ligand for Shigella VirG among the WASP family and determines the host cell type allowing actin-based spreading

26 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24062339

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Mechanism of formin-induced nucleation of actin filaments

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24062339

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Generation of recombinant vaccinia viruses

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24062339

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1083/JCB.201303055

1 reference

18 August 2017

1 reference

18 August 2017

1 reference

PMCID

3787377