The formins: active scaffolds that remodel the cytoskeleton (Q28190582)

FH proteins as cytoskeletal organizers.

Europe PubMed Central

title

The formins: active scaffolds that remodel the cytoskeleton (English)

0 references

0 references

Bradley J Wallar

1

0 references

Arthur S Alberts

series ordinal

2

0 references

language of work or name

English

0 references

publication date

August 2003

0 references

published in

Trends in Cell Biology

0 references

volume

13

0 references

page(s)

435-46

0 references

issue

8

0 references

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900153-3

7 January 2021

FH3, a domain found in formins, targets the fission yeast formin Fus1 to the projection tip during conjugation

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900153-3

7 January 2021

WW and SH3 domains, two different scaffolds to recognize proline-rich ligands

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900153-3

7 January 2021

ForC, a novel type of formin family protein lacking an FH1 domain, is involved in multicellular development in Dictyostelium discoideum

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900153-3

7 January 2021

Nir2, a novel regulator of cell morphogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900153-3

7 January 2021

Role of formins in actin assembly: nucleation and barbed-end association

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900153-3

7 January 2021

Formins: intermediates in signal-transduction cascades that affect cytoskeletal reorganization

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900153-3

7 January 2021

Identification and characterization of a protein containing formin homology (FH1/FH2) domains

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900153-3

7 January 2021

Prediction and analysis of coiled-coil structures

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900153-3

7 January 2021

Yeast formins regulate cell polarity by controlling the assembly of actin cables.

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900153-3

7 January 2021

Cooperation between mDia1 and ROCK in Rho-induced actin reorganization

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900153-3

7 January 2021

Distinct actions and cooperative roles of ROCK and mDia in Rho small G protein-induced reorganization of the actin cytoskeleton in Madin-Darby canine kidney cells

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900153-3

7 January 2021

Interaction of Rho1p target Bni1p with F-actin-binding elongation factor 1alpha: implication in Rho1p-regulated reorganization of the actin cytoskeleton in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900153-3

7 January 2021

Interactions of elongation factor 1alpha with F-actin and beta-actin mRNA: implications for anchoring mRNA in cell protrusions

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900153-3

7 January 2021

p140mDia, a mammalian homolog of Drosophila diaphanous, is a target protein for Rho small GTPase and is a ligand for profilin

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900153-3

7 January 2021

Analysis of RhoA-binding proteins reveals an interaction domain conserved in heterotrimeric G protein beta subunits and the yeast response regulator protein Skn7

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900153-3

7 January 2021

Bni1p, a yeast formin linking cdc42p and the actin cytoskeleton during polarized morphogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900153-3

7 January 2021

FRL, a novel formin-related protein, binds to Rac and regulates cell motility and survival of macrophages

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900153-3

7 January 2021

Disruption of the Diaphanous-related formin Drf1 gene encoding mDia1 reveals a role for Drf3 as an effector for Cdc42

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900153-3

7 January 2021

A conserved binding motif defines numerous candidate target proteins for both Cdc42 and Rac GTPases

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900153-3

7 January 2021

RhoD regulates endosome dynamics through Diaphanous-related Formin and Src tyrosine kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900153-3

7 January 2021

Identification of a carboxyl-terminal diaphanous-related formin homology protein autoregulatory domain

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900153-3

7 January 2021

Cellular motility driven by assembly and disassembly of actin filaments

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900153-3

7 January 2021

An actin nucleation mechanism mediated by Bni1 and profilin

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900153-3

7 January 2021

Mechanism of formin-induced nucleation of actin filaments

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900153-3

7 January 2021

The fission yeast cytokinesis formin Cdc12p is a barbed end actin filament capping protein gated by profilin

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900153-3

7 January 2021

Evolutionary conservation of microtubule-capture mechanisms

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900153-3

7 January 2021

Polarized growth and organelle segregation in yeast: the tracks, motors, and receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900153-3

7 January 2021

Formins direct Arp2/3-independent actin filament assembly to polarize cell growth in yeast

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900153-3

7 January 2021

The diaphanous-related formin mDia1 controls serum response factor activity through its effects on actin polymerization

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900153-3

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900153-3

7 January 2021

Differential usage of signal transduction pathways defines two types of serum response factor target gene

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900153-3

7 January 2021

The Rho family GTPases RhoA, Rac1, and CDC42Hs regulate transcriptional activation by SRF

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900153-3

7 January 2021

Signal-regulated activation of serum response factor is mediated by changes in actin dynamics

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900153-3

7 January 2021

Interaction of serum response factor (SRF) with the Elk-1 B box inhibits RhoA-actin signaling to SRF and potentiates transcriptional activation by Elk-1.

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900153-3

7 January 2021

LIM kinase and Diaphanous cooperate to regulate serum response factor and actin dynamics

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900153-3

7 January 2021

Activation of cardiac gene expression by myocardin, a transcriptional cofactor for serum response factor

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900153-3

7 January 2021

Actin dynamics control SRF activity by regulation of its coactivator MAL

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900153-3

7 January 2021

Roles of the fission yeast formin for3p in cell polarity, actin cable formation and symmetric cell division

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900153-3

7 January 2021

cdc12p, a protein required for cytokinesis in fission yeast, is a component of the cell division ring and interacts with profilin

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900153-3

7 January 2021

Movement of a cytokinesis factor cdc12p to the site of cell division

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900153-3

7 January 2021

Rho1 directs formin-mediated actin ring assembly during budding yeast cytokinesis

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900153-3

7 January 2021

Dynamic localization and function of Bni1p at the sites of directed growth in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900153-3

7 January 2021

Gic2p may link activated Cdc42p to components involved in actin polarization, including Bni1p and Bud6p (Aip3p).

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900153-3

7 January 2021

Actin cable dynamics in budding yeast

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900153-3

7 January 2021

Myosin V orientates the mitotic spindle in yeast

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900153-3

7 January 2021

Bni1p regulates microtubule-dependent nuclear migration through the actin cytoskeleton in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900153-3

7 January 2021

Control of mitotic spindle position by the Saccharomyces cerevisiae formin Bni1p

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900153-3

7 January 2021

Asymmetric loading of Kar9 onto spindle poles and microtubules ensures proper spindle alignment

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900153-3

7 January 2021

Formin-2, polyploidy, hypofertility and positioning of the meiotic spindle in mouse oocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900153-3

7 January 2021

mDia mediates Rho-regulated formation and orientation of stable microtubules

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900153-3

7 January 2021

Coordination of microtubules and the actin cytoskeleton by the Rho effector mDia1.

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900153-3

7 January 2021

Guanine nucleotide exchange factors for Rho GTPases: turning on the switch

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900153-3

7 January 2021

Rho GTPases in cell biology

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900153-3

7 January 2021

Rho3 of Saccharomyces cerevisiae, which regulates the actin cytoskeleton and exocytosis, is a GTPase which interacts with Myo2 and Exo70

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900153-3

7 January 2021

Bni1p and Bnr1p: downstream targets of the Rho family small G-proteins which interact with profilin and regulate actin cytoskeleton in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900153-3

7 January 2021

GTPase Signalling: New Functions for Diaphanous-Related Formins

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900153-3

7 January 2021

The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900153-3

7 January 2021

The formin/diaphanous-related protein, FHOS, interacts with Rac1 and activates transcription from the serum response element

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900153-3

7 January 2021

Contingent phosphorylation/dephosphorylation provides a mechanism of molecular memory in WASP.

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900153-3

7 January 2021

Phosphorylation of the WASP-VCA domain increases its affinity for the Arp2/3 complex and enhances actin polymerization by WASP

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900153-3

7 January 2021

Nonsyndromic deafness DFNA1 associated with mutation of a human homolog of the Drosophila gene diaphanous

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900153-3

7 January 2021

Mechanism of filopodia initiation by reorganization of a dendritic network

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900153-3

7 January 2021

Actin dynamics in growth cones

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900153-3

7 January 2021

Assembly and mechanosensory function of focal contacts

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900153-3

7 January 2021

The Cdc42p GTPase is involved in a G2/M morphogenetic checkpoint regulating the apical-isotropic switch and nuclear division in yeast

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900153-3

7 January 2021

Delphilin: a novel PDZ and formin homology domain-containing protein that synaptically colocalizes and interacts with glutamate receptor delta 2 subunit

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900153-3

7 January 2021

Axon guidance: receptor complexes and signaling mechanisms

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900153-3

7 January 2021

Regulating the actin cytoskeleton during vesicular transport.

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900153-3

7 January 2021

Molecular interaction between limb deformity proteins (formins) and Src family kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900153-3

7 January 2021

In mouse brain profilin I and profilin II associate with regulators of the endocytic pathway and actin assembly

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900153-3

7 January 2021

Rho small G-protein-dependent binding of mDia to an Src homology 3 domain-containing IRSp53/BAIAP2

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900153-3

7 January 2021

mDia-interacting protein acts downstream of Rho-mDia and modifies Src activation and stress fiber formation

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900153-3

7 January 2021

Actin cytoskeleton: are FH proteins local organizers?

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900153-3

7 January 2021

A Formin Homology protein and a profilin are required for cytokinesis and Arp2/3-independent assembly of cortical microfilaments in C. elegans.

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900153-3

7 January 2021

Distinct roles of profilin in cell morphological changes: microspikes, membrane ruffles, stress fibers, and cytokinesis

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900153-3

7 January 2021

The essential role of profilin in the assembly of actin for microspike formation

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900153-3

7 January 2021

Role of actin polymerization and adhesion to extracellular matrix in Rac- and Rho-induced cytoskeletal reorganization

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900153-3

7 January 2021

Association of p60c-src with endosomal membranes in mammalian fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900153-3

7 January 2021

Coordination of cell polarization and migration by the Rho family GTPases requires Src tyrosine kinase activity

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900153-3

7 January 2021

Altered phosphorylation and activation of pp60c-src during fibroblast mitosis

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900153-3

7 January 2021

Phosphorylation of the Src substrate Sam68 by Cdc2 during mitosis

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900153-3

7 January 2021

Immunolocalization of the cellular src protein in interphase and mitotic NIH c-src overexpresser cells

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900153-3

7 January 2021

Elongation factor 1 alpha, translation and the cytoskeleton

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900153-3

7 January 2021

Elongation factor-1 alpha is a novel substrate of rho-associated kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900153-3

7 January 2021

Protein elongation factor EEF1A2 is a putative oncogene in ovarian cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900153-3

7 January 2021

Mother cell-specific HO expression in budding yeast depends on the unconventional myosin myo4p and other cytoplasmic proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900153-3

7 January 2021

Bundling of actin filaments by elongation factor 1 alpha inhibits polymerization at filament ends

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900153-3

7 January 2021

A Rho-dependent signaling pathway operating through myosin localizes beta-actin mRNA in fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900153-3

7 January 2021

Localization and anchoring of mRNA in budding yeast

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900153-3

7 January 2021

Structure of AF3p21, a new member of mixed lineage leukemia (MLL) fusion partner proteins-implication for MLL-induced leukemogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900153-3

7 January 2021

SPIN90 (SH3 protein interacting with Nck, 90 kDa), an adaptor protein that is developmentally regulated during cardiac myocyte differentiation

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900153-3

7 January 2021

A novel neural Wiskott-Aldrich syndrome protein (N-WASP) binding protein, WISH, induces Arp2/3 complex activation independent of Cdc42

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900153-3

7 January 2021

Gapped BLAST and PSI-BLAST: a new generation of protein database search programs

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900153-3

7 January 2021

Effect of capping protein on the kinetics of actin polymerization.

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900153-3

7 January 2021

The social life of actin and microtubules: interaction versus cooperation

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900153-3

7 January 2021

Focal contacts as mechanosensors: externally applied local mechanical force induces growth of focal contacts by an mDia1-dependent and ROCK-independent mechanism

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900153-3

7 January 2021

ROCK and Dia have opposing effects on adherens junctions downstream of Rho

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900153-3

7 January 2021

A homochiral metal-organic porous material for enantioselective separation and catalysis

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900153-3

7 January 2021

The interaction between N-WASP and the Arp2/3 complex links Cdc42-dependent signals to actin assembly

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900153-3

7 January 2021

Negative regulation of fibroblast motility by Ena/VASP proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900153-3

7 January 2021

A human homologue of the Drosophila melanogaster diaphanous gene is disrupted in a patient with premature ovarian failure: evidence for conserved function in oogenesis and implications for human sterility

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900153-3

7 January 2021

The sequence of a 24,152 bp segment from the left arm of chromosome XIV from Saccharomyces cerevisiae between the BNI1 and the POL2 genes

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900153-3

7 January 2021

Cappuccino, a Drosophila maternal effect gene required for polarity of the egg and embryo, is related to the vertebrate limb deformity locus

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900153-3

7 January 2021

The Aspergillus nidulans sepA gene encodes an FH1/2 protein involved in cytokinesis and the maintenance of cellular polarity

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900153-3

7 January 2021

The chicken limb deformity gene encodes nuclear proteins expressed in specific cell types during morphogenesis.

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900153-3

7 January 2021

'Formins': proteins deduced from the alternative transcripts of the limb deformity gene.

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900153-3

7 January 2021

A variant limb deformity transcript expressed in the embryonic mouse limb defines a novel formin

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900153-3

7 January 2021

Formin-2, a novel formin homology protein of the cappuccino subfamily, is highly expressed in the developing and adult central nervous system

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900153-3

7 January 2021

Characterization of fus1 of Schizosaccharomyces pombe: a developmentally controlled function needed for conjugation

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900153-3

7 January 2021

Wnt/Frizzled activation of Rho regulates vertebrate gastrulation and requires a novel Formin homology protein Daam1

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900153-3

7 January 2021

Identification of a novel family of targets of PYK2 related to Drosophila retinal degeneration B (rdgB) protein

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2803%2900153-3

7 January 2021