Reduced dosage of ERF causes complex craniosynostosis in humans and mice and links ERK1/2 signaling to regulation of osteogenesis (Q30540667)

16 October 2017

Reduced dosage of ERF causes complex craniosynostosis in humans and mice and links ERK1/2 signaling to regulation of osteogenesis (English)

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Andrew Oliver Mungo Wilkie

16 October 2017

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27

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24 June 2017

1

Stephen R F Twigg

1 reference

16 October 2017

Aimée L Fenwick

5

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Simon J McGowan

Simon J McGowan

3

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Paul T Sharpe

Paul T Sharpe

20

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Andreas Zaragkoulias

Andreas Zaragkoulias

8

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Alain Verloes

17

Alain Verloes

1 reference

16 October 2017

12

Tracy Lester

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16 October 2017

Elena Vorgia

2

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16 October 2017

Ioanna Peraki

4

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16 October 2017

Vikram P Sharma

6

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16 October 2017

Maryline Allegra

7

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16 October 2017

Elham Sadighi Akha

9

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16 October 2017

Samantha J L Knight

10

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16 October 2017

Helen Lord

11

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16 October 2017

Louise Izatt

13

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16 October 2017

Anne K Lampe

14

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16 October 2017

Shehla N Mohammed

15

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16 October 2017

Fiona J Stewart

16

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16 October 2017

Louise C Wilson

18

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16 October 2017

Chris Healy

19

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16 October 2017

Peter Hammond

21

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Jim Hughes

22

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16 October 2017

Stephen Taylor

23

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16 October 2017

David Johnson

24

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16 October 2017

Steven A Wall

25

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16 October 2017

George Mavrothalassitis

26

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16 October 2017

language of work or name

English

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publication date

27 January 2013

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16 October 2017

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45

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308-313

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3

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describes a project that uses

16 October 2017

SQL

1 reference

26 June 2022

https://europepmc.org/article/PMC/PMC3683605

based on heuristic

inferred from PubMed Central ID database lookup

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20 June 2018

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FGF2-activated ERK mitogen-activated protein kinase enhances Runx2 acetylation and stabilization

20 June 2018

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Cell fate decisions are specified by the dynamic ERK interactome

20 June 2018

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20 June 2018

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20 June 2018

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Extracellular signal-regulated kinase 1 (ERK1) and ERK2 play essential roles in osteoblast differentiation and in supporting osteoclastogenesis

20 June 2018

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Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

20 June 2018

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A Runx2 threshold for the cleidocranial dysplasia phenotype

20 June 2018

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The RAS-dependent ERF control of cell proliferation and differentiation is mediated by c-Myc repression

20 June 2018

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Transcriptional repressor erf determines extraembryonic ectoderm differentiation

20 June 2018

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Detection of novel skeletogenesis target genes by comprehensive analysis of a Runx2(-/-) mouse model

20 June 2018

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The transcriptional ETS2 repressor factor associates with active and inactive Erks through distinct FXF motifs

20 June 2018

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Ets-1 and runx2 regulate transcription of a metastatic gene, osteopontin, in murine colorectal cancer cells

20 June 2018

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Growth of the normal skull vault and its alteration in craniosynostosis: insights from human genetics and experimental studies

20 June 2018

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ERF nuclear shuttling, a continuous monitor of Erk activity that links it to cell cycle progression

20 June 2018

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Genomic screening of fibroblast growth-factor receptor 2 reveals a wide spectrum of mutations in patients with syndromic craniosynostosis

20 June 2018

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Physical interaction of the activator protein-1 factors c-Fos and c-Jun with Cbfa1 for collagenase-3 promoter activation

20 June 2018

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AP-1 and Cbfa/runt physically interact and regulate parathyroid hormone-dependent MMP13 expression in osteoblasts through a new osteoblast-specific element 2/AP-1 composite element

20 June 2018

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Hemorrhage, impaired hematopoiesis, and lethality in mouse embryos carrying a targeted disruption of the Fli1 transcription factor

20 June 2018

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Involvement of Ets transcription factors and targets in osteoblast differentiation and matrix mineralization

20 June 2018

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20 June 2018

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Transcriptional repressor ERF is a Ras/mitogen-activated protein kinase target that regulates cellular proliferation.

20 June 2018

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20 June 2018

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Down's syndrome-like skeletal abnormalities in Ets2 transgenic mice

20 June 2018

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ERF: an ETS domain protein with strong transcriptional repressor activity, can suppress ets-associated tumorigenesis and is regulated by phosphorylation during cell cycle and mitogenic stimulation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683605

Positive and negative factors regulate the transcription of the ETS2 gene via an oncogene-responsive-like unit within the ETS2 promoter region

20 June 2018

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The ERGB/Fli-1 gene: isolation and characterization of a new member of the family of human ETS transcription factors

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683605

Erk pathway and activator protein 1 play crucial roles in FGF2-stimulated premature cranial suture closure

20 June 2018

1 reference

RNA interference and inhibition of MEK-ERK signaling prevent abnormal skeletal phenotypes in a mouse model of craniosynostosis

21 January 2018

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Mutation screening in patients with syndromic craniosynostoses indicates that a limited number of recurrent FGFR2 mutations accounts for severe forms of Pfeiffer syndrome

21 January 2018

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Differential expression patterns of Runx2 isoforms in cranial suture morphogenesis

21 January 2018

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Copy number variation analysis in single-suture craniosynostosis: multiple rare variants including RUNX2 duplication in two cousins with metopic craniosynostosis.

21 January 2018

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Epiblast-restricted Cre expression in MORE mice: a tool to distinguish embryonic vs. extra-embryonic gene function.

21 January 2018

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Pure de novo partial trisomy 6p in a girl with craniosynostosis

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683605

Fgfr1 and Fgfr2 have distinct differentiation- and proliferation-related roles in the developing mouse skull vault

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683605

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26 November 2018

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PubMed

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12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NG.2539

1 reference

release_k7a4xp5iorcgxn52uhb5exizte

16 October 2017

1 reference

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24 November 2022

based on heuristic

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16 October 2017

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