Evidence for dynein and astral microtubule-mediated cortical release and transport of Gαi/LGN/NuMA complex in mitotic cells (Q30538070)

15 August 2017

Evidence for dynein and astral microtubule-mediated cortical release and transport of Gαi/LGN/NuMA complex in mitotic cells (English)

1 reference

15 August 2017

Quansheng Du

6

0 references

author name string

Zhen Zheng

1

1 reference

15 August 2017

Qingwen Wan

2

1 reference

15 August 2017

Jing Liu

3

1 reference

15 August 2017

Huabin Zhu

4

1 reference

15 August 2017

Xiaogang Chu

5

1 reference

15 August 2017

6 February 2013

1 reference

Molecular Biology of the Cell

15 August 2017

1 reference

15 August 2017

24

1 reference

15 August 2017

7

1 reference

15 August 2017

901-913

1 reference

describes a project that uses

15 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3608500/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Cortical dynein is critical for proper spindle positioning in human cells

1 reference

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Cell cycle-regulated cortical dynein/dynactin promotes symmetric cell division by differential pole motion in anaphase

20 June 2018

1 reference

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Regulation of myosin activation during cell-cell contact formation by Par3-Lgl antagonism: entosis without matrix detachment

20 June 2018

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Galpha/LGN-mediated asymmetric spindle positioning does not lead to unequal cleavage of the mother cell in 3-D cultured MDCK cells

20 June 2018

1 reference

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Dynein tethers and stabilizes dynamic microtubule plus ends

20 June 2018

1 reference

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Chromosome- and spindle-pole-derived signals generate an intrinsic code for spindle position and orientation

20 June 2018

1 reference

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Cortical dynein controls microtubule dynamics to generate pulling forces that position microtubule asters

20 June 2018

1 reference

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ABL1 regulates spindle orientation in adherent cells and mammalian skin.

20 June 2018

1 reference

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Dynamic localization of C. elegans TPR-GoLoco proteins mediates mitotic spindle orientation by extrinsic signaling.

20 June 2018

1 reference

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MAP4 and CLASP1 operate as a safety mechanism to maintain a stable spindle position in mitosis

20 June 2018

1 reference

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20 June 2018

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LGN/mInsc and LGN/NuMA Complex Structures Suggest Distinct Functions in Asymmetric Cell Division for the Par3/mInsc/LGN and Gαi/LGN/NuMA Pathways

20 June 2018

1 reference

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Mitotic spindle orientation in asymmetric and symmetric cell divisions during animal development

20 June 2018

1 reference

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Polarity mediates asymmetric trafficking of the Gbeta heterotrimeric G-protein subunit GPB-1 in C. elegans embryos

20 June 2018

1 reference

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A lateral belt of cortical LGN and NuMA guides mitotic spindle movements and planar division in neuroepithelial cells

20 June 2018

1 reference

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Eya1 controls cell polarity, spindle orientation, cell fate and Notch signaling in distal embryonic lung epithelium

20 June 2018

1 reference

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Asymmetric cell divisions promote Notch-dependent epidermal differentiation

20 June 2018

1 reference

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Cell polarity and spindle orientation in the distal epithelium of embryonic lung

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3608500

Intracellular organelles mediate cytoplasmic pulling force for centrosome centration in the Caenorhabditis elegans early embryo

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3608500

Robust control of mitotic spindle orientation in the developing epidermis

20 June 2018

1 reference

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Par3 controls epithelial spindle orientation by aPKC-mediated phosphorylation of apical Pins

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3608500

Ric-8A and Gi alpha recruit LGN, NuMA, and dynein to the cell cortex to help orient the mitotic spindle

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3608500

LGN regulates mitotic spindle orientation during epithelial morphogenesis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3608500

Regulators of the cytoplasmic dynein motor

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3608500

Spindle orientation during asymmetric cell division

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3608500

The actin cytoskeleton in spindle assembly and positioning

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3608500

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3608500

A point mutation to Galphai selectively blocks GoLoco motif binding: direct evidence for Galpha.GoLoco complexes in mitotic spindle dynamics

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3608500

Mechanisms of asymmetric cell division: flies and worms pave the way.

20 June 2018

1 reference

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Mechanisms of asymmetric stem cell division

20 June 2018

1 reference

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Drosophila neuroblast asymmetric divisions: cell cycle regulators, asymmetric protein localization, and tumorigenesis

20 June 2018

1 reference

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Neuroepithelial progenitors undergo LGN-dependent planar divisions to maintain self-renewability during mammalian neurogenesis.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3608500

Heterotrimeric G protein signaling functions with dynein to promote spindle positioning in C. elegans

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3608500

Galphai generates multiple Pins activation states to link cortical polarity and spindle orientation in Drosophila neuroblasts

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3608500

G protein beta gamma subunit interaction with the dynein light-chain component Tctex-1 regulates neurite outgrowth

20 June 2018

1 reference

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Integrin-mediated adhesion orients the spindle parallel to the substratum in an EB1- and myosin X-dependent manner

20 June 2018

1 reference

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Drosophila neuroblast asymmetric cell division: recent advances and implications for stem cell biology

20 June 2018

1 reference

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The Drosophila NuMA Homolog Mud regulates spindle orientation in asymmetric cell division

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3608500

Drosophila Pins-binding protein Mud regulates spindle-polarity coupling and centrosome organization

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3608500

20 June 2018

1 reference

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Asymmetric spindle positioning

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3608500

Spindle positioning by cortical pulling forces

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3608500

Multiple mechanisms regulate NuMA dynamics at spindle poles

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3608500

Mammalian Pins is a conformational switch that links NuMA to heterotrimeric G proteins

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3608500

Dynein/dynactin regulate metaphase spindle length by targeting depolymerizing activities to spindle poles

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3608500

AGS proteins, GPR motifs and the signals processed by heterotrimeric G proteins

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3608500

Return of the GDI: the GoLoco motif in cell division.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3608500

Subcellular localization of LGN during mitosis: evidence for its cortical localization in mitotic cell culture systems and its requirement for normal cell cycle progression

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3608500

The distribution of active force generators controls mitotic spindle position

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3608500

Asymmetrically distributed C. elegans homologs of AGS3/PINS control spindle position in the early embryo

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3608500

Translation of polarity cues into asymmetric spindle positioning in Caenorhabditis elegans embryos

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3608500

A complex of LIN-5 and GPR proteins regulates G protein signaling and spindle function inC. elegans

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3608500

Control of cell polarity and mitotic spindle positioning in animal cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3608500

LGN blocks the ability of NuMA to bind and stabilize microtubules. A mechanism for mitotic spindle assembly regulation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3608500

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3608500

A mammalian Partner of inscuteable binds NuMA and regulates mitotic spindle organization

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3608500

Heterotrimeric G proteins direct two modes of asymmetric cell division in the Drosophila nervous system

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3608500

Proteasome inhibitors: from research tools to drug candidates

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3608500

Regulation of G proteins by covalent modification

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3608500

Polarity controls forces governing asymmetric spindle positioning in the Caenorhabditis elegans embryo

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3608500

A role for the lissencephaly gene LIS1 in mitosis and cytoplasmic dynein function

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3608500

Microtubule interactions with the cell cortex causing nuclear movements in Saccharomyces cerevisiae

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3608500

Mammalian spindle orientation and position respond to changes in cell shape in a dynein-dependent fashion

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3608500

Small molecule inhibitor of mitotic spindle bipolarity identified in a phenotype-based screen

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3608500

Microtubules orient the mitotic spindle in yeast through dynein-dependent interactions with the cell cortex.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3608500

A complex of NuMA and cytoplasmic dynein is essential for mitotic spindle assembly.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3608500

Effects of vinblastine, podophyllotoxin and nocodazole on mitotic spindles. Implications for the role of microtubule dynamics in mitosis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3608500

LGN-dependent orientation of cell divisions in the dermomyotome controls lineage segregation into muscle and dermis.

20 June 2018

1 reference

https://api.crossref.org/works/10.1091%2FMBC.E12-06-0458

Dynein and dynactin are localized to astral microtubules and at cortical sites in mitotic epithelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1091%2FMBC.E12-06-0458

Heterotrimeric G proteins regulate daughter cell size asymmetry in Drosophila neuroblast divisions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1091%2FMBC.E12-06-0458

Distinct roles for Galpha and Gbetagamma in regulating spindle position and orientation in Caenorhabditis elegans embryos.

21 January 2018

1 reference

https://api.crossref.org/works/10.1091%2FMBC.E12-06-0458

Control of planar divisions by the G-protein regulator LGN maintains progenitors in the chick neuroepithelium.

21 January 2018

1 reference

https://api.crossref.org/works/10.1091%2FMBC.E12-06-0458

Coupling of cortical dynein and G alpha proteins mediates spindle positioning in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1091%2FMBC.E12-06-0458

Spindle oscillations during asymmetric cell division require a threshold number of active cortical force generators.

21 January 2018

1 reference

https://api.crossref.org/works/10.1091%2FMBC.E12-06-0458

A protein complex containing Inscuteable and the Galpha-binding protein Pins orients asymmetric cell divisions in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1091%2FMBC.E12-06-0458

The extracellular matrix guides the orientation of the cell division axis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1091%2FMBC.E12-06-0458

PtdIns(3,4,5)P3 regulates spindle orientation in adherent cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1091%2FMBC.E12-06-0458

Latrunculins: novel marine toxins that disrupt microfilament organization in cultured cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1091%2FMBC.E12-06-0458

Rapsynoid/partner of inscuteable controls asymmetric division of larval neuroblasts in Drosophila.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3608500

External forces control mitotic spindle positioning

26 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23389635

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1091/MBC.E12-06-0458

1 reference

15 August 2017

1 reference

15 August 2017

1 reference