BCR-ABL1 kinase inhibits uracil DNA glycosylase UNG2 to enhance oxidative DNA damage and stimulate genomic instability. (Q30537656)

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10 March 2020

title

BCR-ABL1 kinase inhibits uracil DNA glycosylase UNG2 to enhance oxidative DNA damage and stimulate genomic instability (English)

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10 March 2020

0 references

4

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Ewelina Synowiec

8

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Janusz Błasiak

9

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author name string

A Slupianek

1

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R Falinski

2

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P Znojek

3

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S Flis

5

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V Doneddu

6

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D Pytel

7

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A Bellacosa

10

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T Skorski

11

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publication date

9 October 2012

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10 March 2020

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volume

27

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issue

3

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page(s)

629-634

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Rac2-MRC-cIII-generated ROS cause genomic instability in chronic myeloid leukemia stem cells and primitive progenitors

10 March 2020

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14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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hUNG2 is the major repair enzyme for removal of uracil from U:A matches, U:G mismatches, and U in single-stranded DNA, with hSMUG1 as a broad specificity backup

14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/23047475

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

BCR/ABL oncogenic kinase promotes unfaithful repair of the reactive oxygen species-dependent DNA double-strand breaks

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23047475

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/LEU.2012.294

1 reference

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Dimensions Publication ID

10 March 2020

0 references

1 reference

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10 March 2020

PubMed publication ID

23047475

1 reference

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