Macrophages require Skap2 and Sirpα for integrin-stimulated cytoskeletal rearrangement. (Q30533919)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22976304%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

title

Macrophages require Skap2 and Sirpα for integrin-stimulated cytoskeletal rearrangement (English)

1 reference

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13 February 2020

0 references

1

1 reference

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13 February 2020

author name string

Quentin J Baca

2

1 reference

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13 February 2020

Nooreen T Rubin

3

1 reference

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13 February 2020

Lily I Pao

4

1 reference

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13 February 2020

Takashi Matozaki

5

1 reference

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13 February 2020

Clifford A Lowell

6

1 reference

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13 February 2020

David E Golan

7

1 reference

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13 February 2020

Benjamin G Neel

8

1 reference

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13 February 2020

Kenneth D Swanson

9

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13 February 2020

language of work or name

English

0 references

publication date

12 September 2012

1 reference

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13 February 2020

published in

Journal of Cell Science

1 reference

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13 February 2020

volume

125

1 reference

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13 February 2020

issue

Pt 22

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13 February 2020

page(s)

5535-5545

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Comparison of the effects of the PI3K/mTOR inhibitors NVP-BEZ235 and GSK2126458 on tamoxifen-resistant breast cancer cells

13 February 2020

cites work

1 reference

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Cellular responses to extracellular guidance cues

14 July 2018

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Development of monocytes, macrophages, and dendritic cells

14 July 2018

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CD47 is upregulated on circulating hematopoietic stem cells and leukemia cells to avoid phagocytosis

14 July 2018

1 reference

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SLP-76-ADAP adaptor module regulates LFA-1 mediated costimulation and T cell motility

14 July 2018

1 reference

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Biological therapies for inflammatory bowel diseases

14 July 2018

1 reference

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Signal regulatory protein alpha (SIRPalpha)/CD47 interaction and function

14 July 2018

1 reference

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Mechanical control of cAMP signaling through integrins is mediated by the heterotrimeric Galphas protein

14 July 2018

1 reference

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The Skap-hom Dimerization and PH Domains Comprise a 3′-Phosphoinositide-Gated Molecular Switch

14 July 2018

1 reference

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Polymorphism in Sirpa modulates engraftment of human hematopoietic stem cells.

14 July 2018

1 reference

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Loss of integrin alpha(v)beta8 on dendritic cells causes autoimmunity and colitis in mice

14 July 2018

1 reference

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Natalizumab for multiple sclerosis

14 July 2018

1 reference

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ADAP is required for normal alphaIIbbeta3 activation by VWF/GP Ib-IX-V and other agonists.

14 July 2018

1 reference

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The mononuclear phagocyte system

14 July 2018

1 reference

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Regulation of in vitro and in vivo immune functions by the cytosolic adaptor protein SKAP-HOM.

14 July 2018

1 reference

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An essential role for SKAP-55 in LFA-1 clustering on T cells that cannot be substituted by SKAP-55R

14 July 2018

1 reference

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Macrophage colony-stimulating factor receptor induces tyrosine phosphorylation of SKAP55R adaptor and its association with actin

14 July 2018

1 reference

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Deficiency of ADAP/Fyb/SLAP-130 destabilizes SKAP55 in Jurkat T cells

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561861

Negative regulation of phagocytosis in macrophages by the CD47-SHPS-1 system

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561861

Role of the cytoskeleton during leukocyte responses

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561861

Cell shape provides global control of focal adhesion assembly

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561861

Role of the CD47-SHPS-1 system in regulation of cell migration

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561861

Sustained activation of Lyn tyrosine kinase in vivo leads to autoimmunity

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561861

A molecular basis for integrin alphaMbeta 2 ligand binding promiscuity

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561861

Integrins: bidirectional, allosteric signaling machines

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561861

Evidence for a molecular complex consisting of Fyb/SLAP, SLP-76, Nck, VASP and WASP that links the actin cytoskeleton to Fcgamma receptor signalling during phagocytosis.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561861

Inhibition of beta 2 integrin receptor and Syk kinase signaling in monocytes by the Src family kinase Fgr

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561861

Leukocyte transendothelial migration: orchestrating the underlying molecular machinery

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561861

PRAM-1 is a novel adaptor protein regulated by retinoic acid (RA) and promyelocytic leukemia (PML)-RA receptor alpha in acute promyelocytic leukemia cells

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561861

CD47-signal regulatory protein alpha (SIRPalpha) regulates Fcgamma and complement receptor-mediated phagocytosis

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561861

The Yersinia tyrosine phosphatase YopH targets a novel adhesion-regulated signalling complex in macrophages

14 July 2018

1 reference

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SHPS-1 regulates integrin-mediated cytoskeletal reorganization and cell motility

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561861

Cellular signaling in macrophage migration and chemotaxis

14 July 2018

1 reference

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Poly(ethylenimine)-mediated transfection: a new paradigm for gene delivery

14 July 2018

1 reference

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Ligand binding to integrins

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561861

Lipopolysaccharide induces actin reorganization and tyrosine phosphorylation of Pyk2 and paxillin in monocytes and macrophages

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561861

Integrin signalling in neutrophils and macrophages

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561861

SHPS-1 is a scaffold for assembling distinct adhesion-regulated multi-protein complexes in macrophages

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561861

Adaptor proteins Grb2 and Crk couple Pyk2 with activation of specific mitogen-activated protein kinase cascades

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561861

Integrin-associated protein is a ligand for the P84 neural adhesion molecule

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561861

RA70 is a src kinase-associated protein expressed ubiquitously

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561861

Molecular interaction between the Fyn-associated protein SKAP55 and the SLP-76-associated phosphoprotein SLAP-130

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561861

High expression of inhibitory receptor SHPS-1 and its association with protein-tyrosine phosphatase SHP-1 in macrophages

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561861

Signal-regulatory protein is selectively expressed by myeloid and neuronal cells.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561861

FYB (FYN binding protein) serves as a binding partner for lymphoid protein and FYN kinase substrate SKAP55 and a SKAP55-related protein in T cells

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561861

A family of proteins that inhibit signalling through tyrosine kinase receptors

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561861

A novel membrane glycoprotein, SHPS-1, that binds the SH2-domain-containing protein tyrosine phosphatase SHP-2 in response to mitogens and cell adhesion

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561861

Synergistic roles for receptor occupancy and aggregation in integrin transmembrane function.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561861

A monoclonal antibody against an activation epitope on mouse integrin chain beta 1 blocks adhesion of lymphocytes to the endothelial integrin alpha 6 beta 1.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561861

Complement receptors and phagocytosis

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561861

Divalent cation regulation of the function of the leukocyte integrin LFA-1

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561861

The loss of α2β1 integrin suppresses joint inflammation and cartilage destruction in mouse models of rheumatoid arthritis

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561861

Expression of SKAP-HOM in DCs is required for an optimal immune response in vivo

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561861

Inhibition of Src homology 2 domain-containing protein tyrosine phosphatase substrate-1 reduces the severity of collagen-induced arthritis

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561861

Resistance to collagen-induced arthritis in SHPS-1 mutant mice

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561861

Dual regulation of SIRPalpha phosphorylation by integrins and CD47.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561861

Positive Regulation of T Cell Activation and Integrin Adhesion by the Adapter Fyb/Slap

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561861

Leukocyte integrins and inflammation.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561861

Resistance to experimental autoimmune encephalomyelitis and impaired T cell priming by dendritic cells in Src homology 2 domain-containing protein tyrosine phosphatase substrate-1 mutant mice

26 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22976304

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Vedolizumab for the treatment of active ulcerative colitis: a randomized controlled phase 2 dose-ranging study

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22976304

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Survival of mononuclear phagocytes depends on a lineage-specific growth factor that the differentiated cells selectively destroy

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22976304

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1242/JCS.111260

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22976304%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22976304%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22976304%20AND%20SRC:MED&resulttype=core&format=json