High levels of the Mps1 checkpoint protein are protective of aneuploidy in breast cancer cells (Q30499296)

12 October 2017

High levels of the Mps1 checkpoint protein are protective of aneuploidy in breast cancer cells (English)

1 reference

12 October 2017

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2

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12 October 2017

Jewel Daniel

1

1 reference

12 October 2017

Ju-Hyung Woo

series ordinal

3

1 reference

12 October 2017

Kathleen Wilsbach

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4

1 reference

12 October 2017

Edward Gabrielson

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5

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12 October 2017

language of work or name

English

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publication date

14 March 2011

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Proceedings of the National Academy of Sciences of the United States of America

12 October 2017

6

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based on heuristic

inferred from page(s)

published in

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12 October 2017

108

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12 October 2017

5384-5389

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12 October 2017

13

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Small-molecule kinase inhibitors provide insight into Mps1 cell cycle function

12 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3069188

Mechanisms of chromosomal instability.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3069188

Elevating the frequency of chromosome mis-segregation as a strategy to kill tumor cells.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3069188

Impaired Bub1 function in vivo compromises tension-dependent checkpoint function leading to aneuploidy and tumorigenesis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3069188

The aneuploidy paradox in cell growth and tumorigenesis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3069188

Phosphorylation sites in BubR1 that regulate kinetochore attachment, tension, and mitotic exit

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3069188

Aneuploidy affects proliferation and spontaneous immortalization in mammalian cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3069188

Chromosomal instability by inefficient Mps1 auto-activation due to a weakened mitotic checkpoint and lagging chromosomes

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3069188

Examining the link between chromosomal instability and aneuploidy in human cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3069188

Mps1 phosphorylates Borealin to control Aurora B activity and chromosome alignment

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3069188

Distinct genomic aberration patterns are found in familial breast cancer associated with different immunohistochemical subtypes

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3069188

Mps1 kinase promotes sister-kinetochore bi-orientation by a tension-dependent mechanism

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3069188

The genomic landscapes of human breast and colorectal cancers

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3069188

High-resolution aCGH and expression profiling identifies a novel genomic subtype of ER negative breast cancer

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3069188

Regulators of mitotic arrest and ceramide metabolism are determinants of sensitivity to paclitaxel and other chemotherapeutic drugs.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3069188

Mechanisms of mitotic cell death induced by chemotherapy-mediated G2 checkpoint abrogation.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3069188

Mad2 overexpression promotes aneuploidy and tumorigenesis in mice

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3069188

Genomic and transcriptional aberrations linked to breast cancer pathophysiologies

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3069188

The consensus coding sequences of human breast and colorectal cancers

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3069188

Caspase-mediated specific cleavage of BubR1 is a determinant of mitotic progression

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3069188

An expression signature for p53 status in human breast cancer predicts mutation status, transcriptional effects, and patient survival

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3069188

The spindle checkpoint: tension versus attachment.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3069188

Chemical genetics reveals a role for Mps1 kinase in kinetochore attachment during mitosis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3069188

Kinetochore localization of spindle checkpoint proteins: who controls whom?

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3069188

Lethality to human cancer cells through massive chromosome loss by inhibition of the mitotic checkpoint.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3069188

Differential kinetochore requirements for establishment and maintenance of the spindle checkpoint are dependent on the mechanism of checkpoint activation in Saccharomyces cerevisiae.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3069188

Human Mps1 protein kinase is required for centrosome duplication and normal mitotic progression

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3069188

Mutations and aneuploidy: co-conspirators in cancer?

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3069188

Breast cancer classification and prognosis based on gene expression profiles from a population-based study

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3069188

Gene expression profiles of human breast cancer progression

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3069188

Distinct and complementary information provided by use of tissue and DNA microarrays in the study of breast tumor markers

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3069188

Gene expression profiling predicts clinical outcome of breast cancer

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3069188

MAD2 haplo-insufficiency causes premature anaphase and chromosome instability in mammalian cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3069188

Mutation and expression analysis of human BUB1 and BUB1B in aneuploid breast cancer cell lines.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3069188

Genetic instabilities in human cancers

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3069188

Genetic instability of cancer cells is proportional to their degree of aneuploidy

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3069188

Mutations of mitotic checkpoint genes in human cancers

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3069188

Tumour aneuploidy, prognostic parameters and survival in primary breast cancer

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3069188

Increased expression of mitotic checkpoint genes in breast cancer cells with chromosomal instability.

20 June 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1007645108

BubR1 insufficiency causes early onset of aging-associated phenotypes and infertility in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1007645108

Mps1 is a kinetochore-associated kinase essential for the vertebrate mitotic checkpoint.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1007645108

Histone-GFP fusion protein enables sensitive analysis of chromosome dynamics in living mammalian cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1007645108

Genetic reclassification of histologic grade delineates new clinical subtypes of breast cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1007645108

Biological Processes Associated with Breast Cancer Clinical Outcome Depend on the Molecular Subtypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1007645108

Caspases-dependent cleavage of mitotic checkpoint proteins in response to microtubule inhibitor.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3069188

Slippage of mitotic arrest and enhanced tumor development in mice with BubR1 haploinsufficiency

26 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21402910

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The human mitotic checkpoint protein BubR1 regulates chromosome-spindle attachments

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21402910

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1007645108

1 reference

12 October 2017

0 references

1 reference

12 October 2017

1 reference