Identification of a mutant amyloid peptide that predominantly forms neurotoxic protofibrillar aggregates (Q73235288)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12684519%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

title

Identification of a mutant amyloid peptide that predominantly forms neurotoxic protofibrillar aggregates (English)

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2 November 2019

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Isam Qahwash

1

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2 November 2019

Katherine L Weiland

2

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2 November 2019

Yifeng Lu

3

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2 November 2019

Ronald W Sarver

4

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2 November 2019

Rolf F Kletzien

5

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2 November 2019

Riqiang Yan

6

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2 November 2019

language of work or name

English

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publication date

8 April 2003

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Journal of Biological Chemistry

2 November 2019

number of pages

9

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based on heuristic

inferred from page(s)

published in

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2 November 2019

volume

278

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2 November 2019

issue

25

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2 November 2019

page(s)

23187-23195

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Alzheimer's disease and Down's syndrome: Sharing of a unique cerebrovascular amyloid fibril protein

2 November 2019

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Identification of a Novel Aspartic Protease (Asp 2) as β-Secretase

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Purification and cloning of amyloid precursor protein beta-secretase from human brain

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Amyloid diseases: abnormal protein aggregation in neurodegeneration

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Structural and kinetic features of amyloid beta-protein fibrillogenesis.

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An increased percentage of long amyloid beta protein secreted by familial amyloid beta protein precursor (beta APP717) mutants.

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Biochemical evidence for the long-tail form (A beta 1-42/43) of amyloid beta protein as a seed molecule in cerebral deposits of Alzheimer's disease.

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In situ characterization of beta-amyloid in Alzheimer's diseased tissue by synchrotron Fourier transform infrared microspectroscopy

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Vaccination with soluble Abeta oligomers generates toxicity-neutralizing antibodies.

21 January 2018

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Calcium-destabilizing and neurodegenerative effects of aggregated beta-amyloid peptide are attenuated by basic FGF.

21 January 2018

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Beta-amyloid neurotoxicity requires fibril formation and is inhibited by congo red.

21 January 2018

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Amyloid beta protein-induced neuronal cell death: neurotoxic properties of aggregated amyloid beta protein.

21 January 2018

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Oligomeric and fibrillar species of amyloid-beta peptides differentially affect neuronal viability.

21 January 2018

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Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo

21 January 2018

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Amyloid beta-protein fibrillogenesis. Structure and biological activity of protofibrillar intermediates

21 January 2018

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Employing a superior BACE1 cleavage sequence to probe cellular APP processing

21 January 2018

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The carboxy terminus of the beta amyloid protein is critical for the seeding of amyloid formation: implications for the pathogenesis of Alzheimer's disease

21 January 2018

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Information content in the circular dichroism of proteins.

21 January 2018

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Amyloid beta-protein fibrillogenesis. Detection of a protofibrillar intermediate.

21 January 2018

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New Class of Inhibitors of Amyloid-beta Fibril Formation. IMPLICATIONS FOR THE MECHANISM OF PATHOGENESIS IN ALZHEIMER'S DISEASE

21 January 2018

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Arrest of beta-amyloid fibril formation by a pentapeptide ligand

21 January 2018

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21 January 2018

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Comparison of the aggregation properties, secondary structure and apoptotic effects of wild-type, Flemish and Dutch N-terminally truncated amyloid beta peptides

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21 January 2018

Identifiers

DOI

10.1074/JBC.M213298200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12684519%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

1 reference