Blockade of PD-1/B7-H1 interaction restores effector CD8+ T cell responses in a hepatitis C virus core murine model (Q30435498)

15 October 2017

Blockade of PD-1/B7-H1 interaction restores effector CD8+ T cell responses in a hepatitis C virus core murine model (English)

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15 October 2017

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1

John R Lukens

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15 October 2017

Michael W Cruise

2

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15 October 2017

Matthew G Lassen

series ordinal

3

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15 October 2017

Young S Hahn

series ordinal

4

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15 October 2017

language of work or name

English

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publication date

1 April 2008

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15 October 2017

Journal of Immunology

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15 October 2017

180

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15 October 2017

7

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15 October 2017

4875-4884

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describes a project that uses

15 October 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2904552/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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Role of PD-1 and its ligand, B7-H1, in early fate decisions of CD8 T cells

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PD-1:PD-L1 interactions contribute to the functional suppression of virus-specific CD8+ T lymphocytes in the liver.

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Liver-Infiltrating Lymphocytes in Chronic Human Hepatitis C Virus Infection Display an Exhausted Phenotype with High Levels of PD-1 and Low Levels of CD127 Expression

20 June 2018

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Resolution of a chronic viral infection after interleukin-10 receptor blockade

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Hepatitis C virus core protein blocks interferon signaling by interaction with the STAT1 SH2 domain

20 June 2018

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Restoring function in exhausted CD8 T cells during chronic viral infection

20 June 2018

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RETRACTED: B7-DC cross-linking restores antigen uptake and augments antigen-presenting cell function by matured dendritic cells

20 June 2018

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Increased Fas ligand expression of CD4+ T cells by HCV core induces T cell-dependent hepatic inflammation

20 June 2018

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Hepatitis C virus core protein down-regulates transcription of interferon-induced antiviral genes.

20 June 2018

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Negative regulation of NK cell activities by inhibitory receptor CD94/NKG2A leads to altered NK cell-induced modulation of dendritic cell functions in chronic hepatitis C virus infection

20 June 2018

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Hepatitis C virus core selectively suppresses interleukin-12 synthesis in human macrophages by interfering with AP-1 activation

20 June 2018

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Hepatic expansion of a virus-specific regulatory CD8(+) T cell population in chronic hepatitis C virus infection

20 June 2018

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Programmed death-1-programmed death-L1 interaction is essential for induction of regulatory cells by intratracheal delivery of alloantigen

20 June 2018

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Subversion of immune responses by hepatitis C virus: immunomodulatory strategies beyond evasion?

20 June 2018

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PD-1 inhibits antiviral immunity at the effector phase in the liver

20 June 2018

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B7DC/PDL2 promotes tumor immunity by a PD-1-independent mechanism.

20 June 2018

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IFN-alpha antagonistic activity of HCV core protein involves induction of suppressor of cytokine signaling-3.

20 June 2018

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Hepatic T cells and liver tolerance

20 June 2018

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Abnormal priming of CD4(+) T cells by dendritic cells expressing hepatitis C virus core and E1 proteins.

20 June 2018

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Hepatitis C virus core protein inhibits human T lymphocyte responses by a complement-dependent regulatory pathway

20 June 2018

1 reference

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Efficient presentation of exogenous antigen by liver endothelial cells to CD8+ T cells results in antigen-specific T-cell tolerance

20 June 2018

1 reference

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Cellular immune responses persist and humoral responses decrease two decades after recovery from a single-source outbreak of hepatitis C

20 June 2018

1 reference

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Analysis of successful immune responses in persons infected with hepatitis C virus

20 June 2018

1 reference

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The role of virus-specific CD8(+) cells in liver damage and viral control during persistent hepatitis B virus infection

20 June 2018

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Lymphocyte trafficking and regional immunity.

20 June 2018

1 reference

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Induction of cytokine production in naive CD4(+) T cells by antigen-presenting murine liver sinusoidal endothelial cells but failure to induce differentiation toward Th1 cells

20 June 2018

1 reference

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Suppression of host immune response by the core protein of hepatitis C virus: possible implications for hepatitis C virus persistence.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904552

A minimal role for selectins in the recruitment of leukocytes into the inflamed liver microvasculature

20 June 2018

1 reference

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Cytotoxic T cells and viral hepatitis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904552

Quantitative analysis of the peripheral blood cytotoxic T lymphocyte response in patients with chronic hepatitis C virus infection

20 June 2018

1 reference

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Expression of the PD-1 antigen on the surface of stimulated mouse T and B lymphocytes

20 June 2018

1 reference

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Upregulation of class I major histocompatibility complex antigens by interferon gamma is necessary for T-cell-mediated elimination of recombinant adenovirus-infected hepatocytes in vivo

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904552

MHC class I-restricted cytotoxic T lymphocytes to viral antigens destroy hepatocytes in mice infected with E1-deleted recombinant adenoviruses.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904552

Possible mechanism involving T-lymphocyte response to non-structural protein 3 in viral clearance in acute hepatitis C virus infection

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904552

Dysfunction and functional restoration of HCV-specific CD8 responses in chronic hepatitis C virus infection

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904552

Intrahepatic CD8+ T-cell failure during chronic hepatitis C virus infection

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904552

Oscillating CD8(+) T cell effector functions after antigen recognition in the liver.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904552

Rapid functional exhaustion and deletion of CTL following immunization with recombinant adenovirus

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904552

B7-H1 determines accumulation and deletion of intrahepatic CD8(+) T lymphocytes.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904552

The presence of an intrahepatic cytotoxic T lymphocyte response is associated with low viral load in patients with chronic hepatitis C virus infection

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904552

Association of hepatitis C virus-specific CD8+ T cells with viral clearance in acute hepatitis C.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904552

CTL access to tissue antigen is restricted in vivo.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904552

Natural killer cell and hepatic cell interaction via NKG2A leads to dendritic cell-mediated induction of CD4 CD25 T cells with PD-1-dependent regulatory activities

26 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18354211

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.4049/JIMMUNOL.180.7.4875

1 reference

15 October 2017

1 reference

15 October 2017

1 reference