Proteins that bind and move lipids: MsbA and NPC1. (Q30409962)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22117698%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

title

Proteins that bind and move lipids: MsbA and NPC1 (English)

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17 January 2020

2

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17 January 2020

author name string

Gavin King

series ordinal

1

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17 January 2020

publication date

26 November 2011

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22117698%20AND%20SRC:MED&resulttype=core&format=json

Critical Reviews in Biochemistry and Molecular Biology

17 January 2020

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22117698%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

volume

47

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17 January 2020

issue

1

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17 January 2020

page(s)

75-95

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Niemann-Pick C1 Like 1 protein is critical for intestinal cholesterol absorption

17 January 2020

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A role for oxysterol-binding protein-related protein 5 in endosomal cholesterol trafficking

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The reconstituted P-glycoprotein multidrug transporter is a flippase for glucosylceramide and other simple glycosphingolipids

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The reconstituted Escherichia coli MsbA protein displays lipid flippase activity

21 January 2018

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Structure of a cholesterol-binding protein deficient in Niemann-Pick type C2 disease

21 January 2018

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Synthetic and natural Escherichia coli free lipid A express identical endotoxic activities

21 January 2018

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The cholesterol absorption inhibitor ezetimibe acts by blocking the sterol-induced internalization of NPC1L1.

21 January 2018

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Mutations in NPC1 highlight a conserved NPC1-specific cysteine-rich domain

21 January 2018

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Self-association of cholesterol in aqueous solution

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21 January 2018

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21 January 2018

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21 January 2018

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NPC2 facilitates bidirectional transfer of cholesterol between NPC1 and lipid bilayers, a step in cholesterol egress from lysosomes

21 January 2018

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The lethal phenotype caused by null mutations in the Escherichia coli htrB gene is suppressed by mutations in the accBC operon, encoding two subunits of acetyl coenzyme A carboxylase

21 January 2018

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Sequencing, mutational analysis, and transcriptional regulation of theEscherichia coli htrBgene

21 January 2018

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The essential Escherichia coli msbA gene, a multicopy suppressor of null mutations in the htrB gene, is related to the universally conserved family of ATP-dependent translocators.

21 January 2018

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21 January 2018

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Structure of N-Terminal Domain of NPC1 Reveals Distinct Subdomains for Binding and Transfer of Cholesterol

21 January 2018

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21 January 2018

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NPC2, the protein deficient in Niemann-Pick C2 disease, consists of multiple glycoforms that bind a variety of sterols

21 January 2018

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Reversal of defective lysosomal transport in NPC disease ameliorates liver dysfunction and neurodegeneration in the npc1-/- mouse

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Lipid and cholesterol trafficking in NPC.

21 January 2018

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Identification of HE1 as the second gene of Niemann-Pick C disease

21 January 2018

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Topology of SREBP cleavage-activating protein, a polytopic membrane protein with a sterol-sensing domain.

21 January 2018

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Binding between the Niemann-Pick C1 protein and a photoactivatable cholesterol analog requires a functional sterol-sensing domain

21 January 2018

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A porcine homolog of the major secretory protein of human epididymis, HE1, specifically binds cholesterol

21 January 2018

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Mutational analysis and properties of the msbA gene of Escherichia coli, coding for an essential ABC family transporter

21 January 2018

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Lipid transport by mammalian ABC proteins

21 January 2018

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21 January 2018

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Lipid A modification systems in gram-negative bacteria

21 January 2018

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The diverse functions of oxysterol-binding proteins

21 January 2018

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The ATP binding cassette multidrug transporter LmrA and lipid transporter MsbA have overlapping substrate specificities

21 January 2018

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Phospholipid flippase activity of the reconstituted P-glycoprotein multidrug transporter

21 January 2018

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Niemann-Pick type C disease: molecular mechanisms and potential therapeutic approaches

21 January 2018

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21 January 2018

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Sterol metabolism and SREBP activation

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21 January 2018

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Effects of the L511P and D512G mutations on the Escherichia coli ABC transporter MsbA

21 January 2018

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Targeting of NPC1 to late endosomes involves multiple signals, including one residing within the putative sterol-sensing domain

21 January 2018

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Molecular basis of multidrug transport by ABC transporters

21 January 2018

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Characterization of the ATPase activity of P-glycoprotein from multidrug-resistant Chinese hamster ovary cells

21 January 2018

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The ABC transporter MsbA interacts with lipid A and amphipathic drugs at different sites

21 January 2018

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Genetic evidence for nonredundant functional cooperativity between NPC1 and NPC2 in lipid transport

21 January 2018

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ATP binding to the motor domain from an ABC transporter drives formation of a nucleotide sandwich dimer

21 January 2018

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Mapping daunorubicin-binding Sites in the ATP-binding cassette transporter MsbA using site-specific quenching by spin labels

21 January 2018

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The lipopolysaccharide transport system of Gram-negative bacteria

21 January 2018

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Niemann-Pick C2 (NPC2) and intracellular cholesterol trafficking

21 January 2018

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https://api.crossref.org/works/10.3109%2F10409238.2011.636505

MsbA is not required for phospholipid transport in Neisseria meningitidis.

21 January 2018

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Deleting two C-terminal alpha-helices is effective to crystallize the bacterial ABC transporter Escherichia coli MsbA complexed with AMP-PNP.

21 January 2018

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Transport of LDL-derived cholesterol from the NPC1 compartment to the ER involves the trans-Golgi network and the SNARE protein complex

21 January 2018

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ABC lipid transporters: extruders, flippases, or flopless activators?

21 January 2018

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A bacterial antibiotic-resistance gene that complements the human multidrug-resistance P-glycoprotein gene

21 January 2018

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Multidrug resistance mediated by a bacterial homolog of the human multidrug transporter MDR1.

21 January 2018

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Function of the Niemann-Pick type C proteins and their bypass by cyclodextrin

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Niemann-Pick disease type C

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Structure and function of the NPC2 protein

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Identification of surface residues on Niemann-Pick C2 essential for hydrophobic handoff of cholesterol to NPC1 in lysosomes

21 January 2018

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https://api.crossref.org/works/10.3109%2F10409238.2011.636505

MsbA transporter-dependent lipid A 1-dephosphorylation on the periplasmic surface of the inner membrane: topography of francisella novicida LpxE expressed in Escherichia coli

21 January 2018

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https://api.crossref.org/works/10.3109%2F10409238.2011.636505

Lipopolysaccharide: Biosynthetic pathway and structure modification

21 January 2018

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https://api.crossref.org/works/10.3109%2F10409238.2011.636505

Nucleotide dependent packing differences in helical crystals of the ABC transporter MsbA

21 January 2018

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https://api.crossref.org/works/10.3109%2F10409238.2011.636505

Flexibility in the ABC transporter MsbA: Alternating access with a twist

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2011.636505

Extracellular loop C of NPC1L1 is important for binding to ezetimibe

21 January 2018

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Drug-lipid A interactions on the Escherichia coli ABC transporter MsbA.

21 January 2018

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Functional role of transmembrane helix 6 in drug binding and transport by the ABC transporter MsbA.

21 January 2018

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Identification of a protein complex that assembles lipopolysaccharide in the outer membrane of Escherichia coli

21 January 2018

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Structural Basis of Sterol Binding by NPC2, a Lysosomal Protein Deficient in Niemann-Pick Type C2 Disease

21 January 2018

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https://api.crossref.org/works/10.3109%2F10409238.2011.636505

Regulation of sterol transport between membranes and NPC2

21 January 2018

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https://api.crossref.org/works/10.3109%2F10409238.2011.636505

The structure and function of Niemann-Pick C1-like 1 protein

21 January 2018

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https://api.crossref.org/works/10.3109%2F10409238.2011.636505

Cholesterol-regulated translocation of NPC1L1 to the cell surface facilitates free cholesterol uptake

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2011.636505

Function of Escherichia coli MsbA, an essential ABC family transporter, in lipid A and phospholipid biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2011.636505

Alternating access of the putative substrate-binding chamber in the ABC transporter MsbA.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2011.636505

Development of an assay for the intermembrane transfer of cholesterol by Niemann-Pick C2 protein

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2011.636505