Epidemiological and molecular mechanisms aspects linking obesity and cancer. (Q30377470)

21 June 2017

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title

Epidemiological and molecular mechanisms aspects linking obesity and cancer. (English)

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21 June 2017

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Felipe Osório-Costa

1

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21 June 2017

Guilherme Z Rocha

series ordinal

2

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21 June 2017

Marília M Dias

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3

1 reference

21 June 2017

José B C Carvalheira

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4

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21 June 2017

1 March 2009

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Arquivos Brasileiros de Endocrinologia e Metabologia

21 June 2017

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21 June 2017

53

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21 June 2017

2

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21 June 2017

213-226

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Obesity prevalence and trends in Latin-American countries

21 June 2017

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302009000200013

Prevalence of overweight and obesity in the United States, 1999-2004

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302009000200013

Body-mass index and incidence of cancer: a systematic review and meta-analysis of prospective observational studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302009000200013

Overweight, Obesity, and Mortality from Cancer in a Prospectively Studied Cohort of U.S. Adults

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302009000200013

Increased tumor growth in mice with diet-induced obesity: impact of ovarian hormones.

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302009000200013

Energy restriction and the risk of spontaneous mammary tumors in mice: a meta-analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302009000200013

Body mass index and pancreatic cancer risk: A meta-analysis of prospective studies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302009000200013

Body size and risk of colon and rectal cancer in the European Prospective Investigation Into Cancer and Nutrition (EPIC).

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302009000200013

Serum C-peptide, IGFBP-1 and IGFBP-2 and risk of colon and rectal cancers in the European Prospective Investigation into Cancer and Nutrition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302009000200013

Insulin, insulin-like growth factor-I (IGF-I), IGF binding proteins, their biologic interactions, and colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302009000200013

Insulin-like growth factor (IGF)-I, IGF binding protein-3, and cancer risk: systematic review and meta-regression analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302009000200013

Prospective study of colorectal cancer risk in men and plasma levels of insulin-like growth factor (IGF)-I and IGF-binding protein-3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302009000200013

Insulin, the insulin-like growth factor axis, and mortality in patients with nonmetastatic colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302009000200013

Growth factors and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302009000200013

Insulin modulates leptin-induced STAT3 activation in rat hypothalamus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302009000200013

Low plasma adiponectin levels and risk of colorectal cancer in men: a prospective study

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302009000200013

Serum adiponectin is not associated with risk of colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302009000200013

Dual effects of weight and weight gain on breast cancer risk

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302009000200013

Oestrogen exposure and breast cancer risk

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302009000200013

Serum insulin-like growth factor-I and breast cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302009000200013

Insulin-like growth factor binding proteins 1 and 3 and breast cancer outcomes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302009000200013

Adipokines as endocrine, paracrine, and autocrine factors in breast cancer risk and progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302009000200013

Adiponectin and breast cancer risk

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302009000200013

Circulating levels of sex steroid hormones and risk of endometrial cancer in postmenopausal women

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302009000200013

Prediagnostic levels of C-peptide, IGF-I, IGFBP -1, -2 and -3 and risk of endometrial cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302009000200013

Evaluation of dietary, medical and lifestyle risk factors for incident kidney cancer in postmenopausal women.

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302009000200013

Body size and risk of renal cell carcinoma in the European Prospective Investigation into Cancer and Nutrition (EPIC).

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302009000200013

Low adiponectin levels are associated with renal cell carcinoma: a case-control study

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302009000200013

Epidemiology of esophageal adenocarcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302009000200013

Body mass index and adenocarcinomas of the esophagus or gastric cardia: a systematic review and meta-analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302009000200013

A prospective study of BMI and risk of oesophageal and gastric adenocarcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302009000200013

Abdominal obesity and the risk of esophageal and gastric cardia carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302009000200013

Meta-analysis: obesity and the risk for gastroesophageal reflux disease and its complications

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302009000200013

The role of obesity and related metabolic disturbances in cancers of the colon, prostate, and pancreas

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302009000200013

Obesity and cancer risk among white and black United States veterans

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302009000200013

Obesity and risk of pancreatic cancer among postmenopausal women: the Women's Health Initiative (United States).

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302009000200013

Abnormal glucose metabolism and pancreatic cancer mortality

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302009000200013

Circulating insulin-like growth factor axis and the risk of pancreatic cancer in four prospective cohorts

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302009000200013

Body size and composition and prostate cancer risk: systematic review and meta-regression analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302009000200013

Plasma insulin-like growth factor-I and prostate cancer risk: a prospective study

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302009000200013

Obesity and hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302009000200013

Body size and breast cancer risk: findings from the European Prospective Investigation into Cancer And Nutrition (EPIC).

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302009000200013

Obesity and the risk of epithelial ovarian cancer: a systematic review and meta-analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302009000200013

Body size and risk of epithelial ovarian and related cancers: a population-based case-control study

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302009000200013

Height and body mass index and risk of lymphohematopoietic malignancies in two million Norwegian men and women

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302009000200013

Imatinib as a paradigm of targeted therapies

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302009000200013

21 January 2018

Insulin and colon cancer

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302009000200013

Overweight, obesity and cancer: epidemiological evidence and proposed mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302009000200013

Lifestyle determinants of serum insulin-like growth-factor-I (IGF-I), C-peptide and hormone binding protein levels in British women.

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302009000200013

Reduced mammary gland carcinogenesis in transgenic mice expressing a growth hormone antagonist

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302009000200013

Insulin-like growth factor-I activates gene transcription programs strongly associated with poor breast cancer prognosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302009000200013

Dietary energy balance modulates signaling through the Akt/mammalian target of rapamycin pathways in multiple epithelial tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302009000200013

The phosphoinositide 3-kinase pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302009000200013

TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302009000200013

Insulin activation of Rheb, a mediator of mTOR/S6K/4E-BP signaling, is inhibited by TSC1 and 2

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302009000200013

Upstream and downstream of mTOR

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302009000200013

Tumor-promoting phorbol esters and activated Ras inactivate the tuberous sclerosis tumor suppressor complex via p90 ribosomal S6 kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302009000200013

TSC2 mediates cellular energy response to control cell growth and survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302009000200013

Restraining PI3K: mTOR signalling goes back to the membrane.

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302009000200013

Activation of Raf-1 by 14-3-3 proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302009000200013

Hsp-90-associated oncoproteins: multiple targets of geldanamycin and its analogs

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302009000200013

Raf-1 activates MAP kinase-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302009000200013

The extracellular signal-regulated kinase: multiple substrates regulate diverse cellular functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302009000200013

MAPK signal specificity: the right place at the right time

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302009000200013

Body mass index, serum sex hormones, and breast cancer risk in postmenopausal women

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302009000200013

Pathophysiology of sex hormone binding globulin (SHBG): relation to insulin

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302009000200013

Adiposity and sex hormones in postmenopausal breast cancer survivors

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302009000200013

Sex hormone-binding globulin antagonizes the anti-apoptotic effect of estradiol in breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302009000200013

Polycystic ovary syndrome as a form of functional ovarian hyperandrogenism due to dysregulation of androgen secretion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302009000200013

IGF-1 in gynaecology and obstetrics: update 2002.

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302009000200013

Cross-talk between estrogen receptor and growth factor pathways as a molecular target for overcoming endocrine resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302009000200013

Inflammation and cancer: back to Virchow?

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302009000200013

Risk of cancer in ulcerative colitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302009000200013

Respiratory health consequences of environmental tobacco smoke

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302009000200013

Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302009000200013

Modulation of insulin-stimulated degradation of human insulin receptor substrate-1 by Serine 312 phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302009000200013

Phosphorylation of Ser307 in insulin receptor substrate-1 blocks interactions with the insulin receptor and inhibits insulin action

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302009000200013

IKKbeta links inflammation and tumorigenesis in a mouse model of colitis-associated cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302009000200013

IKKbeta couples hepatocyte death to cytokine-driven compensatory proliferation that promotes chemical hepatocarcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302009000200013

Physical activity, obesity, and risk of colorectal adenoma in women (United States)

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302009000200013

Circulating concentrations of insulin-like growth factor I and risk of breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302009000200013

The epidemiology of gastric cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302009000200013

Loss-of-function mutation in Toll-like receptor 4 prevents diet-induced obesity and insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302009000200013

Obesity and cancer: Pathophysiological and biological mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302009000200013

TSC1–TSC2: a complex tale of PKB-mediated S6K regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302009000200013

Body mass index and risk of multiple myeloma: A meta-analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302009000200013

10.1590/S0004-27302009000200013

21 January 2018

Identifiers

DOI

1 reference

21 June 2017

1 reference