Tmprss2 is essential for influenza H1N1 virus pathogenesis in mice. (Q30356975)

20 August 2017

Tmprss2 is essential for influenza H1N1 virus pathogenesis in mice. (English)

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20 August 2017

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6

Stefan Pöhlmann

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Mahmoud M. Bahgat

4

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Klaus Schughart

object named as

Klaus Schughart

Stephanie Stanelle-Bertram

7

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2

object named as

Stephanie Bertram

1 reference

20 August 2017

Bastian Hatesuer

1

1 reference

PMCID

3857797

20 August 2017

Nora Mehnert

3

1 reference

PMCID

3857797

20 August 2017

Peter S Nelson

5

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20 August 2017

5 December 2013

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20 August 2017

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20 August 2017

9

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20 August 2017

12

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20 August 2017

e1003774

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Creative Commons Attribution 4.0 International

20 August 2017

start time

5 December 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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Evidence that TMPRSS2 activates the severe acute respiratory syndrome coronavirus spike protein for membrane fusion and reduces viral control by the humoral immune response

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Inhibition of influenza virus infection in human airway cell cultures by an antisense peptide-conjugated morpholino oligomer targeting the hemagglutinin-activating protease TMPRSS2.

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Efficient activation of the severe acute respiratory syndrome coronavirus spike protein by the transmembrane protease TMPRSS2.

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TMPRSS2 and TMPRSS4 facilitate trypsin-independent spread of influenza virus in Caco-2 cells.

3 June 2018

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Novel insights into proteolytic cleavage of influenza virus hemagglutinin

3 June 2018

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Proteolytic activation of the 1918 influenza virus hemagglutinin

3 June 2018

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Efficient multiplication of human metapneumovirus in Vero cells expressing the transmembrane serine protease TMPRSS2.

3 June 2018

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3 June 2018

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Cleavage of influenza a virus hemagglutinin in human respiratory epithelium is cell associated and sensitive to exogenous antiproteases

3 June 2018

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Characterization of the influenza A virus gene pool in avian species in southern China: was H6N1 a derivative or a precursor of H5N1?

3 June 2018

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High protection of animals lethally infected with influenza virus by aprotinin-rimantadine combination

3 June 2018

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3 June 2018

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Influenza virus hemagglutinin with multibasic cleavage site is activated by furin, a subtilisin-like endoprotease

3 June 2018

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3 June 2018

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Enhancement of the infectivity of influenza A and B viruses by proteolytic cleavage of the hemagglutinin polypeptide

3 June 2018

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3 June 2018

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Mini-plasmin found in the epithelial cells of bronchioles triggers infection by broad-spectrum influenza A viruses and Sendai virus

3 June 2018

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Characterization of lentiviral pseudotypes with influenza H5N1 hemagglutinin and their performance in neutralization assays.

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Suppression of Influenza Virus Replication in Infected Mice by Protease Inhibitors

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Aprotinin aerosol treatment of influenza and paramyxovirus bronchopneumonia of mice

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The Mouse as Model System to Study Host-Pathogen Interactions in Influenza A Infections

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Isolation of factor Xa from chick embryo as the amniotic endoprotease responsible for paramyxovirus activation

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Isolation and characterization of a novel trypsin-like protease found in rat bronchiolar epithelial Clara cells. A possible activator of the viral fusion glycoprotein

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10.1371/JOURNAL.PPAT.1003774

Identifiers

DOI

1 reference

20 August 2017

1 reference

20 August 2017

1 reference

PMCID

3857797