A transmembrane serine protease is linked to the severe acute respiratory syndrome coronavirus receptor and activates virus entry (Q24306622)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21068237%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

title

A transmembrane serine protease is linked to the severe acute respiratory syndrome coronavirus receptor and activates virus entry (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21068237%20AND%20SRC:MED&resulttype=core&format=json

betacoronaviruses spike protein

16 January 2020

main subject

SARS-CoV-1

0 references

0 references

spike glycoprotein [SARS-Cov]

1 reference

based on heuristic

inferred from abstract

angiotensin I converting enzyme 2

0 references

Transmembrane serine protease 2

0 references

1 reference

0 references

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21068237%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

Stanley Perlman

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21068237%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

author name string

Ana Shulla

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21068237%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

Gitanjali Subramanya

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21068237%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

Jincun Zhao

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21068237%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

Tom Gallagher

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21068237%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

language of work or name

English

0 references

publication date

10 November 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21068237%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21068237%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

volume

85

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21068237%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21068237%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

page(s)

873-882

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21068237%20AND%20SRC:MED&resulttype=core&format=json

Proteolytic activation of influenza viruses by serine proteases TMPRSS2 and HAT from human airway epithelium

16 January 2020

cites work

1 reference

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The Coronavirus Spike Protein Is a Class I Virus Fusion Protein: Structural and Functional Characterization of the Fusion Core Complex

19 March 2017

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19 March 2017

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Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirus

19 March 2017

1 reference

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19 March 2017

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19 March 2017

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TMPRSS2 and TMPRSS4 facilitate trypsin-independent spread of influenza virus in Caco-2 cells.

7 April 2017

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Cleavage of the SARS coronavirus spike glycoprotein by airway proteases enhances virus entry into human bronchial epithelial cells in vitro

27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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Importance of cholesterol-rich membrane microdomains in the interaction of the S protein of SARS-coronavirus with the cellular receptor angiotensin-converting enzyme 2.

27 September 2017

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Type II transmembrane serine proteases in development and disease

27 September 2017

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Mechanisms of zoonotic severe acute respiratory syndrome coronavirus host range expansion in human airway epithelium

27 September 2017

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Human coronaviruses: what do they cause?

27 September 2017

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Cleavage of spike protein of SARS coronavirus by protease factor Xa is associated with viral infectivity

27 September 2017

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Highly conserved regions within the spike proteins of human coronaviruses 229E and NL63 determine recognition of their respective cellular receptors

27 September 2017

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Phenotypic analysis of mice lacking the Tmprss2-encoded protease

27 September 2017

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27 September 2017

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27 September 2017

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Protease-mediated enhancement of severe acute respiratory syndrome coronavirus infection

27 September 2017

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Inhibitors of cathepsin L prevent severe acute respiratory syndrome coronavirus entry

27 September 2017

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Tumor necrosis factor-alpha convertase (ADAM17) mediates regulated ectodomain shedding of the severe-acute respiratory syndrome-coronavirus (SARS-CoV) receptor, angiotensin-converting enzyme-2 (ACE2).

27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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Efficient multiplication of human metapneumovirus in Vero cells expressing the transmembrane serine protease TMPRSS2.

27 September 2017

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Cathepsin L functionally cleaves the severe acute respiratory syndrome coronavirus class I fusion protein upstream of rather than adjacent to the fusion peptide

30 May 2018

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30 May 2018

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30 May 2018

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Selective and specific regulation of ectodomain shedding of angiotensin-converting enzyme 2 by tumor necrosis factor alpha-converting enzyme

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020023

Activation of a membrane-bound serine protease matriptase on the cell surface.

29 November 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020023

The human airway trypsin-like protease modulates the urokinase receptor (uPAR, CD87) structure and functions.

29 November 2018

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29 November 2018

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29 November 2018

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Type II transmembrane serine proteases

29 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21068237

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1128/JVI.02062-10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21068237%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21068237%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

1 reference