Beta-amyloid protein structure determines the nature of cytokine release from rat microglia. (Q30351145)

20 June 2017

Beta-amyloid protein structure determines the nature of cytokine release from rat microglia. (English)

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20 June 2017

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4

Marianne Schultzberg

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20 June 2017

Catharina Lindberg

1

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20 June 2017

Maj-Linda Bardyl Selenica

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2

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20 June 2017

Anita Westlind-Danielsson

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3

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20 June 2017

1 January 2005

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Journal of Molecular Neuroscience

20 June 2017

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20 June 2017

27

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20 June 2017

1-12

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20 June 2017

1

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Interleukin-1 beta and interleukin-6 are elevated in the cerebrospinal fluid of Alzheimer's and de novo Parkinson's disease patients.

20 June 2017

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12 December 2020

Scavenging of Alzheimer's amyloid beta-protein by microglia in culture.

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12 December 2020

Specific domains of beta-amyloid from Alzheimer plaque elicit neuron killing in human microglia.

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12 December 2020

Deciphering the genesis and fate of amyloid beta-protein yields novel therapies for Alzheimer disease

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12 December 2020

Interleukin-6 and α-2-macroglobulin indicate an acute-phase state in Alzheimer's disease cortices

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12 December 2020

Oxidation of methionine 35 attenuates formation of amyloid beta -peptide 1-40 oligomers

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12 December 2020

Soluble oligomers of beta amyloid (1-42) inhibit long-term potentiation but not long-term depression in rat dentate gyrus.

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12 December 2020

Amyloid beta-protein fibrillogenesis. Detection of a protofibrillar intermediate.

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12 December 2020

Brain interleukin 1 and S-100 immunoreactivity are elevated in Down syndrome and Alzheimer disease

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12 December 2020

Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins

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12 December 2020

Immune reactive cells in senile plaques and cognitive decline in Alzheimer's disease

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12 December 2020

Characterization of beta-amyloid peptide from human cerebrospinal fluid

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12 December 2020

A possible model of senile plaques using synthetic amyloid beta-protein and rat glial culture.

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12 December 2020

Anti-inflammatory drugs and Alzheimer disease.

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12 December 2020

Reciprocal control of inflammatory cytokines, IL-1 and IL-6, and β-amyloid production in cultures

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12 December 2020

Natural oligomers of the amyloid-beta protein specifically disrupt cognitive function

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12 December 2020

beta-Amyloid-(1-42) is a major component of cerebrovascular amyloid deposits: implications for the pathology of Alzheimer disease

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12 December 2020

Evidence for excitoprotective and intraneuronal calcium-regulating roles for secreted forms of the beta-amyloid precursor protein.

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12 December 2020

Activation of microglial cells by beta-amyloid protein and interferon-gamma.

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12 December 2020

Overproduction of IFN-gamma and TNF-alpha from natural killer (NK) cells is associated with abnormal NK reactivity and cognitive derangement in Alzheimer's disease

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12 December 2020

Macrophage colony-stimulating factor augments beta-amyloid-induced interleukin-1, interleukin-6, and nitric oxide production by microglial cells

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12 December 2020

Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis

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12 December 2020

Oligomeric and fibrillar species of amyloid-beta peptides differentially affect neuronal viability.

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12 December 2020

Inflammatory mechanisms in Alzheimer's disease.

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12 December 2020

Peripherally administered antibodies against amyloid beta-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease

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12 December 2020

Nonfibrillar diffuse amyloid deposition due to a gamma(42)-secretase site mutation points to an essential role for N-truncated A beta(42) in Alzheimer's disease

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12 December 2020

Microglia and cytokines in neurological disease, with special reference to AIDS and Alzheimer's disease

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12 December 2020

Amyloid-beta peptide fragments p3 and p4 induce pro-inflammatory cytokine and chemokine production in vitro and in vivo.

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12 December 2020

Interleukin-1 expression in different plaque types in Alzheimer's disease: significance in plaque evolution.

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12 December 2020

Association of A beta 40-positive senile plaques with microglial cells in the brains of patients with Alzheimer's disease and in non-demented aged individuals.

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12 December 2020

Spherical aggregates of beta-amyloid (amylospheroid) show high neurotoxicity and activate tau protein kinase I/glycogen synthase kinase-3beta

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12 December 2020

β-Amyloid stimulates glial cells in vitro to produce growth factors that accumulate in senile plaques in Alzheimer's disease

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12 December 2020

Intracerebral production of tumor necrosis factor-alpha, a local neuroprotective agent, in Alzheimer disease and vascular dementia.

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12 December 2020

Alzheimer's disease-affected brain: presence of oligomeric A beta ligands (ADDLs) suggests a molecular basis for reversible memory loss

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12 December 2020

Longitudinal study of inflammatory factors in serum, cerebrospinal fluid, and brain tissue in Alzheimer disease: interleukin-1beta, interleukin-6, interleukin-1 receptor antagonist, tumor necrosis factor-alpha, the soluble tumor necrosis factor rece

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12 December 2020

Amyloid-beta peptide activates cultured astrocytes: morphological alterations, cytokine induction and nitric oxide release.

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12 December 2020

Does IFNgamma play a role in neurodegeneration?

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12 December 2020

Decreased levels of intrathecal interleukin 1 receptor antagonist in Alzheimer's disease.

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12 December 2020

Spontaneous in vitro formation of supramolecular beta-amyloid structures, "betaamy balls", by beta-amyloid 1-40 peptide

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12 December 2020

Expression of amyloid precursor protein mRNAs in endothelial, neuronal and glial cells: modulation by interleukin-1.

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12 December 2020

Propentofylline protects neurons in culture from death triggered by macrophage or microglial secretory products.

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12 December 2020

Inflammation and Alzheimer's disease

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12 December 2020

Protofibrillar intermediates of amyloid beta-protein induce acute electrophysiological changes and progressive neurotoxicity in cortical neurons.

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12 December 2020

Rapid photochemical cross-linking--a new tool for studies of metastable, amyloidogenic protein assemblies.

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12 December 2020

Observation of metastable Abeta amyloid protofibrils by atomic force microscopy

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12 December 2020

Immunological aspects of microglia: relevance to Alzheimer's disease

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12 December 2020

Interleukin-1 receptor antagonist protein and mRNA in the rat adrenal gland

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12 December 2020

Effects of rofecoxib or naproxen vs placebo on Alzheimer disease progression: a randomized controlled trial

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12 December 2020

Possible Involvement of Small Oligomers of Amyloid-β Peptides in 15-Deoxy-Δ12,14 Prostaglandin J2-Sensitive Microglial Activation

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12 December 2020

Circulating cytokines in Alzheimer's disease.

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12 December 2020

Soluble multimeric Alzheimer beta(1-40) pre-amyloid complexes in dilute solution.

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12 December 2020

Activation of human macrophages by amyloid-beta is attenuated by astrocytes.

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12 December 2020

Inflammatory processes in Alzheimer's disease

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12 December 2020

Is amyloidogenesis during Alzheimer's disease due to an IL-1-/IL-6-mediated 'acute phase response' in the brain?

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12 December 2020

Cell biology of the amyloid beta-protein precursor and the mechanism of Alzheimer's disease

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12 December 2020

Up-regulation of the inflammatory cytokines IFN-gamma and IL-12 and down-regulation of IL-4 in cerebral cortex regions of APP(SWE) transgenic mice.

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12 December 2020

Interleukin-6 is not altered in cerebrospinal fluid of first-degree relatives and patients with Alzheimer's disease.

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12 December 2020

Microglial cells and amyloid beta protein (A beta) deposition; association with A beta 40-containing plaques

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12 December 2020

The carboxy terminus of the beta amyloid protein is critical for the seeding of amyloid formation: implications for the pathogenesis of Alzheimer's disease

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12 December 2020

Unchanged levels of interleukins, neopterin, interferon-gamma and tumor necrosis factor-alpha in cerebrospinal fluid of patients with dementia of the Alzheimer type.

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12 December 2020

Amyloid beta peptide potentiates cytokine secretion by interleukin-1 beta-activated human astrocytoma cells

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12 December 2020

Visualization of A beta 42(43) and A beta 40 in senile plaques with end-specific A beta monoclonals: evidence that an initially deposited species is A beta 42(43).

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12 December 2020

Nonsteroidal anti-inflammatory drugs for the prevention of Alzheimer's disease: a systematic review

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12 December 2020

alpha-1-antichymotrypsin interaction with A beta (1-40) inhibits fibril formation but does not affect the peptide toxicity

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12 December 2020

Correlation between elevated levels of amyloid beta-peptide in the brain and cognitive decline

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12 December 2020

beta-Amyloid induces increased release of interleukin-1 beta from lipopolysaccharide-activated human monocytes

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12 December 2020

Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease

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12 December 2020

Cerebrospinal fluid interleukin-1 beta (IL-1 beta) in Alzheimer's disease and neurological disorders

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12 December 2020

Increased cerebrospinal fluid fas (Apo-1) levels in Alzheimer's disease. Relationship with IL-6 concentrations

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12 December 2020

Unique physicochemical profile of beta-amyloid peptide variant Abeta1-40E22G protofibrils: conceivable neuropathogen in arctic mutant carriers.

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12 December 2020

Early Abeta accumulation and progressive synaptic loss, gliosis, and tangle formation in AD brain

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12 December 2020

Cytokines, chemokines, and cytokine receptors in human microglia

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12 December 2020

beta-Amyloid stimulation of microglia and monocytes results in TNFalpha-dependent expression of inducible nitric oxide synthase and neuronal apoptosis.

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12 December 2020

Immunohistochemical localization of interleukin-1beta, interleukin-1 receptor antagonist and interleukin-1beta converting enzyme/caspase-1 in the rat brain after peripheral administration of kainic acid.

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12 December 2020

Identifiers

DOI

10.1385/JMN:27:1:001

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Dimensions Publication ID

20 June 2017

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