Amyloid beta oligomers (A beta(1-42) globulomer) suppress spontaneous synaptic activity by inhibition of P/Q-type calcium currents. (Q30179416)

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1 January 2020

title

Amyloid beta oligomers (A beta(1-42) globulomer) suppress spontaneous synaptic activity by inhibition of P/Q-type calcium currents (English)

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Calcium voltage-gated channel subunit alpha1 A

1 January 2020

main subject

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GOA release 2020-03-11

response to amyloid-beta

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GOA release 2020-03-11

author name string

Volker Nimmrich

1

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1 January 2020

Christiane Grimm

2

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1 January 2020

Andreas Draguhn

3

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1 January 2020

Stefan Barghorn

4

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1 January 2020

Alexander Lehmann

5

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1 January 2020

Hans Schoemaker

6

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1 January 2020

Heinz Hillen

7

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1 January 2020

Gerhard Gross

8

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1 January 2020

Ulrich Ebert

9

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Claus Bruehl

10

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language of work or name

English

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publication date

1 January 2008

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1 January 2020

published in

Journal of Neuroscience

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volume

28

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page(s)

788-797

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issue

4

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Soluble amyloid beta peptide concentration as a predictor of synaptic change in Alzheimer's disease

1 January 2020

cites work

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12 December 2020

Soluble pool of Abeta amyloid as a determinant of severity of neurodegeneration in Alzheimer's disease

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12 December 2020

Apolipoprotein E is essential for amyloid deposition in the APP(V717F) transgenic mouse model of Alzheimer's disease

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12 December 2020

Developmental changes in calcium channel types mediating central synaptic transmission.

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12 December 2020

Dendritic spines shaped by synaptic activity

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12 December 2020

Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo

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12 December 2020

Roscovitine: a novel regulator of P/Q-type calcium channels and transmitter release in central neurons

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12 December 2020

Neurodegenerative disease: amyloid pores from pathogenic mutations.

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12 December 2020

Alzheimer's disease is a synaptic failure

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12 December 2020

Presynaptic Ca2+ channels: a functional patchwork

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12 December 2020

Synaptic slaughter in Alzheimer's disease

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12 December 2020

Block of long-term potentiation by naturally secreted and synthetic amyloid beta-peptide in hippocampal slices is mediated via activation of the kinases c-Jun N-terminal kinase, cyclin-dependent kinase 5, and p38 mitogen-activated protein kinase as

1 reference

12 December 2020

Permeabilization of lipid bilayers is a common conformation-dependent activity of soluble amyloid oligomers in protein misfolding diseases

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12 December 2020

Synaptic targeting by Alzheimer's-related amyloid beta oligomers.

1 reference

12 December 2020

Natural oligomers of the amyloid-beta protein specifically disrupt cognitive function

1 reference

12 December 2020

Globular amyloid beta-peptide oligomer - a homogenous and stable neuropathological protein in Alzheimer's disease

1 reference

12 December 2020

Presynaptic Ca2+ channels--integration centers for neuronal signaling pathways.

1 reference

12 December 2020

D1-like dopamine receptors selectively block P/Q-type calcium channels to reduce glutamate release onto cholinergic basal forebrain neurones of immature rats

1 reference

12 December 2020

A Oligomer-Induced Aberrations in Synapse Composition, Shape, and Density Provide a Molecular Basis for Loss of Connectivity in Alzheimer's Disease

1 reference

12 December 2020

Abeta oligomers induce neuronal oxidative stress through an N-methyl-D-aspartate receptor-dependent mechanism that is blocked by the Alzheimer drug memantine

1 reference

12 December 2020

Natural oligomers of the Alzheimer amyloid-beta protein induce reversible synapse loss by modulating an NMDA-type glutamate receptor-dependent signaling pathway

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12 December 2020

Developmental changes in presynaptic calcium channels coupled to glutamate release in cultured rat hippocampal neurons.

1 reference

12 December 2020

Calcium and transmitter release

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12 December 2020

Pharmacological identification of two types of presynaptic voltage-dependent calcium channels at CA3-CA1 synapses of the hippocampus.

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12 December 2020

Rat hippocampal neurons in dispersed cell culture.

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12 December 2020

Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease

1 reference

12 December 2020

Central cholinergic systems and cognition

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12 December 2020

Development of HVA and LVA calcium currents in pyramidal CA1 neurons in the hippocampus of the rat.

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12 December 2020

The cholinergic system in Alzheimer's disease

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12 December 2020

Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins

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12 December 2020

10.1523/JNEUROSCI.4771-07.2008

Identifiers

DOI

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