Occludin OCEL-domain interactions are required for maintenance and regulation of the tight junction barrier to macromolecular flux (Q30009590)

21 May 2017

Occludin OCEL-domain interactions are required for maintenance and regulation of the tight junction barrier to macromolecular flux (English)

1 reference

21 May 2017

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Mary M Buschmann

1

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21 May 2017

Le Shen

2

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21 May 2017

Harsha Rajapakse

3

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21 May 2017

David R Raleigh

4

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21 May 2017

Yitang Wang

5

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21 May 2017

Yingmin Wang

6

1 reference

21 May 2017

Amulya Lingaraju

7

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21 May 2017

Juanmin Zha

8

1 reference

21 May 2017

Elliot Abbott

9

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21 May 2017

Erin M McAuley

10

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21 May 2017

Lydia A Breskin

11

1 reference

21 May 2017

Licheng Wu

12

1 reference

21 May 2017

Kenneth Anderson

13

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21 May 2017

Jerrold R Turner

14

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21 May 2017

Christopher R Weber

15

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21 May 2017

7 August 2013

1 reference

Molecular Biology of the Cell

21 May 2017

1 reference

21 May 2017

24

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21 May 2017

3056-3068

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21 May 2017

19

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describes a project that uses

21 May 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3784380/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

The occludin and ZO-1 complex, defined by small angle X-ray scattering and NMR, has implications for modulating tight junction permeability

1 reference

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Tight junction-associated MARVEL proteins marveld3, tricellulin, and occludin have distinct but overlapping functions

22 May 2017

1 reference

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Physiology and function of the tight junction

22 May 2017

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Intestinal mucosal barrier function in health and disease

22 May 2017

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Identification and Analysis of Occludin Phosphosites: A Combined Mass Spectrometry and Bioinformatics Approach

22 May 2017

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High-throughput mapping of a dynamic signaling network in mammalian cells

22 May 2017

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Interferon-gamma and tumor necrosis factor-alpha synergize to induce intestinal epithelial barrier dysfunction by up-regulating myosin light chain kinase expression

22 May 2017

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A differentiation-dependent splice variant of myosin light chain kinase, MLCK1, regulates epithelial tight junction permeability

22 May 2017

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Regulated expression of claudin-4 decreases paracellular conductance through a selective decrease in sodium permeability

22 May 2017

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Protein interactions at the tight junction. Actin has multiple binding partners, and ZO-1 forms independent complexes with ZO-2 and ZO-3

22 May 2017

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The tight junction protein ZO-1 establishes a link between the transmembrane protein occludin and the actin cytoskeleton

22 May 2017

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Occludin confers adhesiveness when expressed in fibroblasts

22 May 2017

1 reference

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Occludin: a novel integral membrane protein localizing at tight junctions

22 May 2017

1 reference

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Direct association of occludin with ZO-1 and its possible involvement in the localization of occludin at tight junctions

22 May 2017

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TNFR2 activates MLCK-dependent tight junction dysregulation to cause apoptosis-mediated barrier loss and experimental colitis.

22 May 2017

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Protein kinase cβ phosphorylates occludin regulating tight junction trafficking in vascular endothelial growth factor-induced permeability in vivo

3 June 2018

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MicroRNA regulation of intestinal epithelial tight junction permeability

3 June 2018

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Occludin S408 phosphorylation regulates tight junction protein interactions and barrier function

3 June 2018

1 reference

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Occludin regulates macromolecule flux across the intestinal epithelial tight junction barrier

3 June 2018

1 reference

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Tight junction pore and leak pathways: a dynamic duo.

3 June 2018

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Occludin is required for cytokine-induced regulation of tight junction barriers

3 June 2018

1 reference

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MLCK-dependent exchange and actin binding region-dependent anchoring of ZO-1 regulate tight junction barrier function

3 June 2018

1 reference

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Caveolin-1-dependent occludin endocytosis is required for TNF-induced tight junction regulation in vivo

3 June 2018

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Epithelial myosin light chain kinase activation induces mucosal interleukin-13 expression to alter tight junction ion selectivity

3 June 2018

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ZO-1 stabilizes the tight junction solute barrier through coupling to the perijunctional cytoskeleton

3 June 2018

1 reference

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Zonula occludens-1 and -2 are cytosolic scaffolds that regulate the assembly of cellular junctions

3 June 2018

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Tricellulin forms a barrier to macromolecules in tricellular tight junctions without affecting ion permeability

3 June 2018

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Occludin phosphorylation and ubiquitination regulate tight junction trafficking and vascular endothelial growth factor-induced permeability

3 June 2018

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Molecular basis for cation selectivity in claudin-2-based paracellular pores: identification of an electrostatic interaction site

3 June 2018

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Loss of occludin affects tricellular localization of tricellulin.

3 June 2018

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The density of small tight junction pores varies among cell types and is increased by expression of claudin-2.

3 June 2018

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LIGHT signals directly to intestinal epithelia to cause barrier dysfunction via cytoskeletal and endocytic mechanisms.

3 June 2018

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The guanylate kinase domain of the MAGUK PSD-95 binds dynamically to a conserved motif in MAP1a

3 June 2018

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IFN-gamma-induced TNFR2 expression is required for TNF-dependent intestinal epithelial barrier dysfunction

3 June 2018

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Coordinated epithelial NHE3 inhibition and barrier dysfunction are required for TNF-mediated diarrhea in vivo

3 June 2018

1 reference

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Epithelial myosin light chain kinase-dependent barrier dysfunction mediates T cell activation-induced diarrhea in vivo

3 June 2018

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Structure of the conserved cytoplasmic C-terminal domain of occludin: identification of the ZO-1 binding surface

3 June 2018

1 reference

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Actin depolymerization disrupts tight junctions via caveolae-mediated endocytosis

3 June 2018

1 reference

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A strategy to identify stable membrane-permeant peptide inhibitors of myosin light chain kinase.

3 June 2018

1 reference

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Multiple protein interactions involving proposed extracellular loop domains of the tight junction protein occludin

3 June 2018

1 reference

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Setting up a selective barrier at the apical junction complex

3 June 2018

1 reference

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Filtration, diffusion, and molecular sieving through porous cellulose membranes.

3 June 2018

1 reference

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Anti-tumor necrosis factor treatment restores the gut barrier in Crohn's disease

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784380

Claudins create charge-selective channels in the paracellular pathway between epithelial cells

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784380

Occludin modulates organization of perijunctional circumferential actin in rat endothelial cells

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784380

Occludin regulates actin cytoskeleton in endothelial cells

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784380

Complex phenotype of mice lacking occludin, a component of tight junction strands.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784380

The coiled-coil domain of occludin can act to organize structural and functional elements of the epithelial tight junction

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784380

Multiple domains of occludin are involved in the regulation of paracellular permeability

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784380

A dominant mutant of occludin disrupts tight junction structure and function

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784380

Autocrine regulation of epithelial permeability by hypoxia: role for polarized release of tumor necrosis factor alpha.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784380

Phosphorylation of occludin correlates with occludin localization and function at the tight junction

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784380

COOH terminus of occludin is required for tight junction barrier function in early Xenopus embryos

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784380

A synthetic peptide corresponding to the extracellular domain of occludin perturbs the tight junction permeability barrier

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784380

Functional dissociation of paracellular permeability and transepithelial electrical resistance and disruption of the apical-basolateral intramembrane diffusion barrier by expression of a mutant tight junction membrane protein

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784380

Structural basis for physiological regulation of paracellular pathways in intestinal epithelia

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784380

Loss of claudins 2 and 15 from mice causes defects in paracellular Na+ flow and nutrient transport in gut and leads to death from malnutrition

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784380

Phosphorylation of Tyr-398 and Tyr-402 in occludin prevents its interaction with ZO-1 and destabilizes its assembly at the tight junctions

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784380

Myosin light chain phosphorylation regulates barrier function by remodeling tight junction structure

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784380

Epithelial transport and barrier function in occludin-deficient mice

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784380

Mechanism of TNF-{alpha} modulation of Caco-2 intestinal epithelial tight junction barrier: role of myosin light-chain kinase protein expression

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784380

Knockdown of occludin expression leads to diverse phenotypic alterations in epithelial cells.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784380

A membrane-permeant peptide that inhibits MLC kinase restores barrier function in in vitro models of intestinal disease.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784380

Ion transport through cell membrane

26 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23924897

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Physiological regulation of epithelial tight junctions is associated with myosin light-chain phosphorylation

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23924897