Epithelial myosin light chain kinase-dependent barrier dysfunction mediates T cell activation-induced diarrhea in vivo (Q34014510)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16184195%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

title

Epithelial myosin light chain kinase-dependent barrier dysfunction mediates T cell activation-induced diarrhea in vivo (English)

1 reference

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7 January 2020

0 references

1 reference

1

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7 January 2020

Daniel Watterson

6

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7 January 2020

author name string

Terrence A Barrett

2

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7 January 2020

Yueming Tang

3

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7 January 2020

Jon B Meddings

4

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7 January 2020

Linda J Van Eldik

5

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7 January 2020

Lane L Clarke

7

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7 January 2020

Randall J Mrsny

8

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7 January 2020

Jerrold R Turner

9

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7 January 2020

language of work or name

English

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publication date

22 September 2005

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Journal of Clinical Investigation

7 January 2020

published in

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7 January 2020

volume

115

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7 January 2020

page(s)

2702-2715

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7 January 2020

issue

10

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Actin depolymerization disrupts tight junctions via caveolae-mediated endocytosis

7 January 2020

cites work

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Interferon-gamma and tumor necrosis factor-alpha synergize to induce intestinal epithelial barrier dysfunction by up-regulating myosin light chain kinase expression

5 July 2018

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5 July 2018

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Proinflammatory cytokines disrupt epithelial barrier function by apoptosis-independent mechanisms

5 July 2018

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5 July 2018

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5 July 2018

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Constitutive activation of Rho proteins by CNF-1 influences tight junction structure and epithelial barrier function.

5 July 2018

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5 July 2018

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Tumor necrosis factor regulates intestinal epithelial cell migration by receptor-dependent mechanisms

5 July 2018

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T cell activation causes diarrhea by increasing intestinal permeability and inhibiting epithelial Na+/K+-ATPase.

5 July 2018

1 reference

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Thiazolidinone CFTR inhibitor identified by high-throughput screening blocks cholera toxin-induced intestinal fluid secretion.

5 July 2018

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Anti-tumor necrosis factor treatment restores the gut barrier in Crohn's disease

5 July 2018

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Defining the roles of perforin, Fas/FasL, and tumour necrosis factor alpha in T cell induced mucosal damage in the mouse intestine

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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New isolation technique to study apoptosis in human intestinal epithelial cells

5 July 2018

1 reference

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Structural and functional regulation of tight junctions by RhoA and Rac1 small GTPases

5 July 2018

1 reference

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Autocrine regulation of epithelial permeability by hypoxia: role for polarized release of tumor necrosis factor alpha.

5 July 2018

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Enteropathogenic Escherichia coli-induced myosin light chain phosphorylation alters intestinal epithelial permeability

5 July 2018

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Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension

5 July 2018

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Dual role for AlF4(-)-sensitive G proteins in the function of T84 epithelial cells: transport and barrier effects

5 July 2018

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Phosphorylation and activation of myosin by Rho-associated kinase (Rho-kinase)

5 July 2018

1 reference

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Regulation of myosin phosphatase by Rho and Rho-associated kinase (Rho-kinase)

5 July 2018

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5 July 2018

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CD45RO expression on circulating CD19+ B cells in Crohn's disease correlates with intestinal permeability

5 July 2018

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Increases in guinea pig small intestinal transepithelial resistance induced by osmotic loads are accompanied by rapid alterations in absorptive-cell tight-junction structure

5 July 2018

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5 July 2018

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Crohn's disease--a permeability disorder of the tight junction?

5 July 2018

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5 July 2018

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5 July 2018

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The intestinal permeability barrier. A hypothesis as to its regulation and involvement in Crohn's disease

5 July 2018

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5 July 2018

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Mechanism of TNF-{alpha} modulation of Caco-2 intestinal epithelial tight junction barrier: role of myosin light-chain kinase protein expression

5 July 2018

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Intestinal infection with Giardia spp. reduces epithelial barrier function in a myosin light chain kinase-dependent fashion.

29 October 2018

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A membrane-permeant peptide that inhibits MLC kinase restores barrier function in in vitro models of intestinal disease.

29 October 2018

1 reference

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Intestinal NaCl transport in NHE2 and NHE3 knockout mice

29 October 2018

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29 October 2018

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29 October 2018

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Intestinal permeability is increased in a proportion of spouses of patients with Crohn's disease

29 October 2018

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29 October 2018

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29 October 2018

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Leaks in the epithelial barrier caused by spontaneous and TNF-alpha-induced single-cell apoptosis.

29 October 2018

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29 October 2018

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Regulation of TNF-alpha-induced reorganization of the actin cytoskeleton and cell-cell junctions by Rho, Rac, and Cdc42 in human endothelial cells.

29 October 2018

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29 October 2018

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29 October 2018

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29 October 2018

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12 December 2020

Biochemical regulation of the nonmuscle myosin light chain kinase isoform in bovine endothelium

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12 December 2020

Caspase-dependent cleavage of myosin light chain kinase (MLCK) is involved in TNF-alpha-mediated bovine pulmonary endothelial cell apoptosis

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

Tumor necrosis factor inhibitor ameliorates murine intestinal graft-versus-host disease

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12 December 2020

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12 December 2020

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12 December 2020

Intestinal permeability and the prediction of relapse in Crohn's disease

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Identifiers

DOI

10.1172/JCI24970

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16184195%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16184195%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

1 reference