Vinexin β Interacts with Hepatitis C Virus NS5A, Modulating Its Hyperphosphorylation To Regulate Viral Propagation (Q30009166)

21 May 2017

Vinexin β Interacts with Hepatitis C Virus NS5A, Modulating Its Hyperphosphorylation To Regulate Viral Propagation (English)

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21 May 2017

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Wei Xiong

1

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21 May 2017

Jie Yang

2

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21 May 2017

Mingzhen Wang

3

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21 May 2017

Hailong Wang

4

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21 May 2017

Zhipeng Rao

5

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21 May 2017

Cheng Zhong

6

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21 May 2017

Xiu Xin

7

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21 May 2017

Lin Mo

8

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21 May 2017

Shujuan Yu

9

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21 May 2017

Chao Shen

10

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21 May 2017

Congyi Zheng

11

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21 May 2017

13 May 2015

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21 May 2017

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21 May 2017

89

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21 May 2017

7385-7400

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21 May 2017

14

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describes a project that uses

21 May 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4473562/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Hepatitis C virus NS5A inhibits mixed lineage kinase 3 to block apoptosis

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The lipid kinase phosphatidylinositol-4 kinase III alpha regulates the phosphorylation status of hepatitis C virus NS5A

22 May 2017

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Diacylglycerol acyltransferase-1 localizes hepatitis C virus NS5A protein to lipid droplets and enhances NS5A interaction with the viral capsid core

22 May 2017

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Three-dimensional architecture and biogenesis of membrane structures associated with hepatitis C virus replication

22 May 2017

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Annexin A2 is involved in the formation of hepatitis C virus replication complex on the lipid raft

22 May 2017

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Polo-like kinase 1 is involved in hepatitis C virus replication by hyperphosphorylating NS5A

22 May 2017

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Essential Role of Cyclophilin A for Hepatitis C Virus Replication and Virus Production and Possible Link to Polyprotein Cleavage Kinetics

22 May 2017

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A Conserved Proline between Domains II and III of Hepatitis C Virus NS5A Influences both RNA Replication and Virus Assembly

22 May 2017

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Hepatitis C virus infection protein network

22 May 2017

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The adaptor protein MITA links virus-sensing receptors to IRF3 transcription factor activation

22 May 2017

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Architects of assembly: roles of Flaviviridae non-structural proteins in virion morphogenesis

22 May 2017

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NS3 Helicase Domains Involved in Infectious Intracellular Hepatitis C Virus Particle Assembly

22 May 2017

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Regulation of Hepatitis C Virion Production via Phosphorylation of the NS5A Protein

22 May 2017

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Human butyrate-induced transcript 1 interacts with hepatitis C virus NS5A and regulates viral replication

22 May 2017

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Casein kinase 1alpha interacts with RIP1 and regulates NF-kappaB activation

22 May 2017

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The lipid droplet is an important organelle for hepatitis C virus production

22 May 2017

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Studying Hepatitis C Virus: Making the Best of a Bad Virus

22 May 2017

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Hepatitis C virus RNA replication is regulated by FKBP8 and Hsp90

22 May 2017

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The Isoform of Protein Kinase CKI Is Responsible for Hepatitis C Virus NS5A Hyperphosphorylation

22 May 2017

1 reference

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The SH3 binding motif of HCV [corrected] NS5A protein interacts with Bin1 and is important for apoptosis and infectivity

22 May 2017

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Protein kinase A-dependent increase in WAVE2 expression induced by the focal adhesion protein vinexin

22 May 2017

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Human VAP-B is involved in hepatitis C virus replication through interaction with NS5A and NS5B

22 May 2017

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Robust hepatitis C virus infection in vitro

22 May 2017

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Structure of the zinc-binding domain of an essential component of the hepatitis C virus replicase

22 May 2017

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Identification of FBL2 as a geranylgeranylated cellular protein required for hepatitis C virus RNA replication

22 May 2017

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A novel isoform of Vinexin, Vinexin gamma, regulates Sox9 gene expression through activation of MAPK cascade in mouse fetal gonad

22 May 2017

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Hepatitis C virus NS5A-mediated activation of phosphoinositide 3-kinase results in stabilization of cellular beta-catenin and stimulation of beta-catenin-responsive transcription

22 May 2017

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Further studies on hepatitis C virus NS5A-SH3 domain interactions: identification of residues critical for binding and implications for viral RNA replication and modulation of cell signalling

22 May 2017

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Vinexin beta interacts with the non-phosphorylated AF-1 domain of retinoid receptor gamma (RARgamma) and represses RARgamma-mediated transcription

22 May 2017

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Phosphorylation of hepatitis C virus nonstructural protein 5A modulates its protein interactions and viral RNA replication

22 May 2017

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The hepatitis C virus NS5A protein binds to members of the Src family of tyrosine kinases and regulates kinase activity

22 May 2017

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Mutations that permit efficient replication of hepatitis C virus RNA in Huh-7 cells prevent productive replication in chimpanzees

22 May 2017

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Vinexin, CAP/ponsin, ArgBP2: a novel adaptor protein family regulating cytoskeletal organization and signal transduction

22 May 2017

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Efficient initiation of HCV RNA replication in cell culture

22 May 2017

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Hepatitis C virus RNA polymerase and NS5A complex with a SNARE-like protein

22 May 2017

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Modulation of hepatitis C virus NS5A hyperphosphorylation by nonstructural proteins NS3, NS4A, and NS4B

22 May 2017

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Replication of subgenomic hepatitis C virus RNAs in a hepatoma cell line

22 May 2017

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NS5A, a nonstructural protein of hepatitis C virus, binds growth factor receptor-bound protein 2 adaptor protein in a Src homology 3 domain/ligand-dependent manner and perturbs mitogenic signaling

22 May 2017

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Vinexin: a novel vinculin-binding protein with multiple SH3 domains enhances actin cytoskeletal organization

22 May 2017

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The NS5A/NS5 proteins of viruses from three genera of the family flaviviridae are phosphorylated by associated serine/threonine kinases

22 May 2017

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A novel, multifuntional c-Cbl binding protein in insulin receptor signaling in 3T3-L1 adipocytes

22 May 2017

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ArgBP2, a multiple Src homology 3 domain-containing, Arg/Abl-interacting protein, is phosphorylated in v-Abl-transformed cells and localized in stress fibers and cardiocyte Z-disks

22 May 2017

1 reference

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Structural determinants of peptide-binding orientation and of sequence specificity in SH3 domains

22 May 2017

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Hepatitis C virus RNA replication and assembly: living on the fat of the land

22 May 2017

1 reference

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Phosphatidylserine-specific phospholipase A1 involved in hepatitis C virus assembly through NS2 complex formation

3 June 2018

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Hepatitis C virus NS5A: enigmatic but still promiscuous 10 years on!

3 June 2018

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Involvement of hepatitis C virus NS5A hyperphosphorylation mediated by casein kinase I-α in infectious virus production

3 June 2018

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Insights into the complexity and functionality of hepatitis C virus NS5A phosphorylation

3 June 2018

1 reference

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GPS2 is required for the association of NS5A with VAP-A and hepatitis C virus replication

3 June 2018

1 reference

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Hepatocyte nuclear factor 4α and downstream secreted phospholipase A2 GXIIB regulate production of infectious hepatitis C virus

3 June 2018

1 reference

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Global control of hepatitis C: where challenge meets opportunity

3 June 2018

1 reference

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Modulation of hepatitis C virus genome encapsidation by nonstructural protein 4B

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4473562

Construction and identification of recombinant lentiviral vector containing HIV-1 Tat gene and its expression in 293T cells

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4473562

Contrasting roles of mitogen-activated protein kinases in cellular entry and replication of hepatitis C virus: MKNK1 facilitates cell entry

3 June 2018

1 reference

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Intragenic complementation of hepatitis C virus NS5A RNA replication-defective alleles

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4473562

A hepatitis C virus NS5A phosphorylation site that regulates RNA replication

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4473562

Focal adhesion kinase (FAK) mediates the induction of pro-oncogenic and fibrogenic phenotypes in hepatitis C virus (HCV)-infected cells

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4473562

CD40 inhibits replication of hepatitis C virus in primary human hepatocytes by c-Jun N terminal kinase activation independent from the interferon pathway

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4473562

Nonstructural 5A protein of hepatitis C virus regulates heat shock protein 72 for its own propagation

3 June 2018

1 reference

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Proline-serine-threonine phosphatase-interacting protein 2 (PSTPIP2), a host membrane-deforming protein, is critical for membranous web formation in hepatitis C virus replication

3 June 2018

1 reference

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Peptidyl-prolyl isomerase Pin1 is a cellular factor required for hepatitis C virus propagation

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4473562

Hepatitis C virus infection induces the expression of amphiregulin, a factor related to the activation of cellular survival pathways and required for efficient viral assembly

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4473562

A new natural α-helical peptide from the venom of the scorpion Heterometrus petersii kills HCV.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4473562

Efficient hepatitis C virus particle formation requires diacylglycerol acyltransferase-1

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4473562

Mechanisms of HCV survival in the host

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4473562

ArgBP2 and the SoHo family of adapter proteins in oncogenic diseases

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4473562

Construction of the Vero cell culture system that can produce infectious HCV particles

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4473562

Essential roles of ERK-mediated phosphorylation of vinexin in cell spreading, migration and anchorage-independent growth

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4473562

Phosphorylation of hepatitis C virus NS5A nonstructural protein: a new paradigm for phosphorylation-dependent viral RNA replication?

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4473562

Hepatitis C virus NS5A is a direct substrate of casein kinase I-alpha, a cellular kinase identified by inhibitor affinity chromatography using specific NS5A hyperphosphorylation inhibitors

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4473562

Vinexin beta regulates the phosphorylation of epidermal growth factor receptor on the cell surface

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4473562

Hepatitis C virus NS5A: tales of a promiscuous protein

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4473562

IFN-regulatory factor 3-dependent gene expression is defective in Tbk1-deficient mouse embryonic fibroblasts

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4473562

Vinexin beta regulates the anchorage dependence of ERK2 activation stimulated by epidermal growth factor.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4473562

Vinexin forms a signaling complex with Sos and modulates epidermal growth factor-induced c-Jun N-terminal kinase/stress-activated protein kinase activities.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4473562

3 June 2018

Identifiers

DOI

10.1128/JVI.00567-15

1 reference

21 May 2017

0 references

1 reference