Potential therapeutic applications of autophagy (Q29622862)

Europe PubMed Central

title

Potential therapeutic applications of autophagy (English)

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30 April 2017

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4

Klionsky DJ

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30 April 2017

Rubinsztein DC

1

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Gestwicki JE

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2

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Murphy LO

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3

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=17396135

30 April 2017

language of work or name

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30 April 2017

publication date

April 2007

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Nature Reviews Drug Discovery

30 April 2017

published in

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volume

6

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page(s)

304-12

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issue

4

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PKR-dependent autophagic degradation of herpes simplex virus type 1.

30 April 2017

cites work

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Endogenous MHC class II processing of a viral nuclear antigen after autophagy.

31 March 2020

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Autophagy and its possible roles in nervous system diseases, damage and repair

31 March 2020

1 reference

Autophagy signaling and the cogwheels of cancer

31 March 2020

1 reference

Autophagy, mitochondrial quality control, and oncogenesis

31 March 2020

1 reference

Autophagy and cancer therapy

31 March 2020

1 reference

Unraveling the role of autophagy in cancer

31 March 2020

1 reference

Autophagy: a highway for Porphyromonas gingivalis in endothelial cells

31 March 2020

1 reference

Autophagy recognizes intracellular Salmonella enterica serovar Typhimurium in damaged vacuoles

31 March 2020

1 reference

The two faces of autophagy: Coxiella and Mycobacterium

31 March 2020

1 reference

Mouse infection by Legionella, a model to analyze autophagy

31 March 2020

1 reference

31 March 2020

Shigella and autophagy

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Autophagy in immune defense against Mycobacterium tuberculosis

31 March 2020

1 reference

Cytoplasmic bacteria and the autophagic pathway

31 March 2020

1 reference

Autophagy vs. Group A Streptococcus

31 March 2020

1 reference

Chaperone-mediated autophagy in aging and disease

31 March 2020

1 reference

Autophagy: molecular machinery for self-eating

31 March 2020

1 reference

A Unified Nomenclature for Yeast Autophagy-Related Genes

31 March 2020

1 reference

Autophagy in the eukaryotic cell

31 March 2020

1 reference

Two ubiquitin-like conjugation systems essential for autophagy

31 March 2020

1 reference

Molecular mechanisms and regulation of specific and nonspecific autophagy pathways in yeast

31 March 2020

1 reference

Beclin-phosphatidylinositol 3-kinase complex functions at the trans-Golgi network

31 March 2020

1 reference

Distinct classes of phosphatidylinositol 3'-kinases are involved in signaling pathways that control macroautophagy in HT-29 cells

31 March 2020

1 reference

Two distinct Vps34 phosphatidylinositol 3-kinase complexes function in autophagy and carboxypeptidase Y sorting in Saccharomyces cerevisiae

31 March 2020

1 reference

Induction of autophagy and inhibition of tumorigenesis by beclin 1

31 March 2020

1 reference

Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene

31 March 2020

1 reference

Starvation and ULK1-dependent cycling of mammalian Atg9 between the TGN and endosomes

31 March 2020

1 reference

Apg9p/Cvt7p is an integral membrane protein required for transport vesicle formation in the Cvt and autophagy pathways

31 March 2020

1 reference

Phosphorylation of ribosomal protein S6 is inhibitory for autophagy in isolated rat hepatocytes

31 March 2020

1 reference

Tor-mediated induction of autophagy via an Apg1 protein kinase complex

31 March 2020

1 reference

Autophagy and p70S6 kinase.

31 March 2020

1 reference

Tor, a phosphatidylinositol kinase homologue, controls autophagy in yeast

31 March 2020

1 reference

The TOR pathway: a target for cancer therapy

31 March 2020

1 reference

Phase II trial of temsirolimus (CCI-779) in recurrent glioblastoma multiforme: a North Central Cancer Treatment Group Study

31 March 2020

1 reference

Sirolimus: its role in nephrology.

31 March 2020

1 reference

mSin1 is necessary for Akt/PKB phosphorylation, and its isoforms define three distinct mTORC2s

31 March 2020

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Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex

31 March 2020

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Prolonged rapamycin treatment inhibits mTORC2 assembly and Akt/PKB

31 March 2020

1 reference

mTOR and cancer: insights into a complex relationship

31 March 2020

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Lithium induces autophagy by inhibiting inositol monophosphatase

31 March 2020

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Unlocking the secrets of cell signaling

31 March 2020

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Protective roles for induction of autophagy in multiple proteinopathies

31 March 2020

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Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death

31 March 2020

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Pivotal role of oligomerization in expanded polyglutamine neurodegenerative disorders.

31 March 2020

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Aggregate-prone proteins with polyglutamine and polyalanine expansions are degraded by autophagy

31 March 2020

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α-Synuclein Is Degraded by Both Autophagy and the Proteasome

31 March 2020

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Increased susceptibility of cytoplasmic over nuclear polyglutamine aggregates to autophagic degradation

31 March 2020

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Autophagy regulates the processing of amino terminal huntingtin fragments

31 March 2020

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Regulation of intracellular accumulation of mutant Huntingtin by Beclin 1

31 March 2020

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Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease

31 March 2020

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Rapamycin alleviates toxicity of different aggregate-prone proteins

31 March 2020

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Degradation of Amyotrophic Lateral Sclerosis-linked Mutant Cu,Zn-Superoxide Dismutase Proteins by Macroautophagy and the Proteasome

31 March 2020

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Emerging role for autophagy in the removal of aggresomes in Schwann cells.

31 March 2020

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Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice

31 March 2020

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Loss of autophagy in the central nervous system causes neurodegeneration in mice

31 March 2020

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Reversal of neuropathology and motor dysfunction in a conditional model of Huntington's disease

31 March 2020

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Rapamycin pre-treatment protects against apoptosis

31 March 2020

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Initiation of apoptosis and autophagy by the Bcl-2 antagonist HA14-1.

31 March 2020

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Bcl-2 down-regulation causes autophagy in a caspase-independent manner in human leukemic HL60 cells

31 March 2020

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Aggregate formation inhibits proteasomal degradation of polyglutamine proteins.

31 March 2020

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Autophagy is a defense mechanism inhibiting BCG and Mycobacterium tuberculosis survival in infected macrophages

31 March 2020

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Autophagy defends cells against invading group A Streptococcus

31 March 2020

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Cellular autophagy: surrender, avoidance and subversion by microorganisms

31 March 2020

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DRAM, a p53-induced modulator of autophagy, is critical for apoptosis

31 March 2020

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p53, Autophagy and tumor suppression

31 March 2020

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Autophagy in cancer: good, bad, or both?

31 March 2020

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Autophagy in health and disease: a double-edged sword

31 March 2020

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Antitumoral activity of rapamycin in renal angiomyolipoma associated with tuberous sclerosis complex

31 March 2020

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Autophagy inhibition enhances therapy-induced apoptosis in a Myc-induced model of lymphoma

31 March 2020

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New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway

31 March 2020

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Human tumor mutants in the p110alpha subunit of PI3K.

31 March 2020

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Signalling by PI3K isoforms: insights from gene-targeted mice.

31 March 2020

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Isoform-specific phosphoinositide 3-kinase inhibitors as therapeutic agents.

31 March 2020

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Autophagy promotes tumor cell survival and restricts necrosis, inflammation, and tumorigenesis

31 March 2020

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Growth factor regulation of autophagy and cell survival in the absence of apoptosis

31 March 2020

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A pharmacological map of the PI3-K family defines a role for p110alpha in insulin signaling

31 March 2020

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A dual PI3 kinase/mTOR inhibitor reveals emergent efficacy in glioma

31 March 2020

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Upstream and downstream of mTOR

31 March 2020

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Microtubules support production of starvation-induced autophagosomes but not their targeting and fusion with lysosomes.

31 March 2020

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Inhibition of macroautophagy triggers apoptosis

31 March 2020

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An inhibitor of Bcl-2 family proteins induces regression of solid tumours

31 March 2020

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Thiol proteases: inhibitors and potential therapeutic targets

31 March 2020

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The crystal structure of human Atg4b, a processing and de-conjugating enzyme for autophagosome-forming modifiers

31 March 2020

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Features of selective kinase inhibitors

31 March 2020

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Tyrosine kinase inhibition: an approach to drug development

31 March 2020

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Modulation of protein-protein interactions with small organic molecules

31 March 2020

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Harnessing chaperones to generate small-molecule inhibitors of amyloid beta aggregation

31 March 2020

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Inhibition of protein-protein association by small molecules: approaches and progress

31 March 2020

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Bafilomycin A1 prevents maturation of autophagic vacuoles by inhibiting fusion between autophagosomes and lysosomes in rat hepatoma cell line, H-4-II-E cells

31 March 2020

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7 January 2021

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=17396135

30 April 2017

Consolidated OpenCitations Corpus – April 2017

Dimensions Publication ID

2427521

1035714440

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2427521

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Consolidated OpenCitations Corpus – April 2017

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=17396135

2 references

30 April 2017

Consolidated OpenCitations Corpus – April 2017