Phenotypic plasticity and the epigenetics of human disease (Q29614515)

Europe PubMed Central

title

Phenotypic plasticity and the epigenetics of human disease (English)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=17522677

30 April 2017

main subject

phenotypic plasticity

0 references

author name string

Feinberg AP

series ordinal

1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=17522677

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=17522677

30 April 2017

language of work or name

1 reference

30 April 2017

publication date

24 May 2007

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=17522677

30 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=17522677

30 April 2017

volume

447

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=17522677

30 April 2017

page(s)

433-40

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=17522677

30 April 2017

issue

7143

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=17522677

Microdeletion of LIT1 in familial Beckwith-Wiedemann syndrome

30 April 2017

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Microdeletions in the human H19 DMR result in loss of IGF2 imprinting and Beckwith-Wiedemann syndrome.

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Epigenetic alterations of H19 and LIT1 distinguish patients with Beckwith-Wiedemann syndrome with cancer and birth defects

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Alternative mechanisms associated with silencing of CDKN1C in Beckwith-Wiedemann syndrome

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Imprinting defects on human chromosome 15.

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Imprints of disease at GNAS1.

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Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2

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Molecular genetics of Rett syndrome: when DNA methylation goes unrecognized

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Chromosome instability and immunodeficiency syndrome caused by mutations in a DNA methyltransferase gene

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Defective B-cell-negative selection and terminal differentiation in the ICF syndrome.

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Rubinstein-Taybi syndrome caused by mutations in the transcriptional co-activator CBP

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Hypomethylation distinguishes genes of some human cancers from their normal counterparts

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The history of cancer epigenetics

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The human let-7a-3 locus contains an epigenetically regulated microRNA gene with oncogenic function.

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Hypomethylation-linked activation of PAX2 mediates tamoxifen-stimulated endometrial carcinogenesis.

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Epigenetic changes may contribute to the formation and spontaneous regression of retinoblastoma

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The fundamental role of epigenetic events in cancer

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Aberrant CpG-island methylation has non-random and tumour-type-specific patterns.

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Epigenetic remodeling in colorectal cancer results in coordinate gene suppression across an entire chromosome band.

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Preference of DNA methyltransferases for CpG islands in mouse embryonic stem cells

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Chromosome-wide and promoter-specific analyses identify sites of differential DNA methylation in normal and transformed human cells

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Distinct effects on gene expression of chemical and genetic manipulation of the cancer epigenome revealed by a multimodality approach.

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A model for embryonal rhabdomyosarcoma tumorigenesis that involves genome imprinting

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Relaxation of imprinted genes in human cancer.

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Relaxation of insulin-like growth factor II gene imprinting implicated in Wilms' tumour

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Genomic imprinting and gene activation in cancer

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Loss of imprinting of IGF2 and not H19 in breast cancer, adjacent normal tissue and derived fibroblast cultures

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7 January 2021

Frequent IGF2/H19 domain epigenetic alterations and elevated IGF2 expression in epithelial ovarian cancer

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7 January 2021

Epigenetic alteration at the DLK1-GTL2 imprinted domain in human neoplasia: analysis of neuroblastoma, phaeochromocytoma and Wilms' tumour

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7 January 2021

The polycomb group protein EZH2 is involved in progression of prostate cancer

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7 January 2021

Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer

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7 January 2021

A histone H3 methyltransferase controls DNA methylation in Neurospora crassa

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7 January 2021

Histone and DNA methylation defects at Hox genes in mice expressing a SET domain-truncated form of Mll.

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7 January 2021

Direct interaction between DNMT1 and G9a coordinates DNA and histone methylation during replication

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The C-terminal SET domains of ALL-1 and TRITHORAX interact with the INI1 and SNR1 proteins, components of the SWI/SNF complex

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7 January 2021

Truncating mutations of hSNF5/INI1 in aggressive paediatric cancer

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7 January 2021

Haploinsufficiency of NSD1 causes Sotos syndrome

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Activation of mouse genes in transformed cells

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7 January 2021

Biallelic inactivation of hMLH1 by epigenetic gene silencing, a novel mechanism causing human MSI cancers.

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7 January 2021

Histone modifications and silencing prior to DNA methylation of a tumor suppressor gene.

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7 January 2021

Risk of cancer during the first four years of life in children from The Beckwith-Wiedemann Syndrome Registry

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7 January 2021

Loss of imprinting in normal tissue of colorectal cancer patients with microsatellite instability

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7 January 2021

Loss of IGF2 imprinting: a potential marker of colorectal cancer risk

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7 January 2021

Loss of insulin-like growth factor-II imprinting and the presence of screen-detected colorectal adenomas in women.

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7 January 2021

CpG island methylator phenotype in colorectal cancer

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Opposing effects of DNA hypomethylation on intestinal and liver carcinogenesis

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Induction of Tumors in Mice by Genomic Hypomethylation

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Chromosomal Instability and Tumors Promoted by DNA Hypomethylation

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Suppression of intestinal neoplasia by DNA hypomethylation.

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Heterozygous disruption of Hic1 predisposes mice to a gender-dependent spectrum of malignant tumors.

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7 January 2021

Loss of imprinting of Igf2 alters intestinal maturation and tumorigenesis in mice

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7 January 2021

Global loss of imprinting leads to widespread tumorigenesis in adult mice

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7 January 2021

The epigenetic progenitor origin of human cancer

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Soluble IGF2 receptor rescues Apc(Min/+) intestinal adenoma progression induced by Igf2 loss of imprinting.

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7 January 2021

Loss of Imprinting of Insulin-Like Growth Factor-II (IGF2) Gene in Distinguishing Specific Biologic Subtypes of Wilms Tumor

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7 January 2021

Reprogramming of a melanoma genome by nuclear transplantation

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7 January 2021

Distinct epigenetic changes in the stromal cells of breast cancers

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7 January 2021

A bivalent chromatin structure marks key developmental genes in embryonic stem cells

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7 January 2021

Continuous MLL-ENL expression is necessary to establish a "Hox Code" and maintain immortalization of hematopoietic progenitor cells

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7 January 2021

Transformation from committed progenitor to leukaemia stem cell initiated by MLL-AF9.

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7 January 2021

Polycomb complexes repress developmental regulators in murine embryonic stem cells

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7 January 2021

Evidence from Turner's syndrome of an imprinted X-linked locus affecting cognitive function.

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7 January 2021

Identification of a cluster of X-linked imprinted genes in mice

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7 January 2021

Autism as a strongly genetic disorder: evidence from a British twin study

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7 January 2021

Neuroanatomic variation in monozygotic twin pairs discordant for the narrow phenotype for autism

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7 January 2021

Genetic or epigenetic difference causing discordance between monozygotic twins as a clue to molecular basis of mental disorders

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7 January 2021

Further characterization of the autism susceptibility locus AUTS1 on chromosome 7q.

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7 January 2021

Genome-wide scan of bipolar disorder in 65 pedigrees: supportive evidence for linkage at 8q24, 18q22, 4q32, 2p12, and 13q12

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7 January 2021

Epigenetics, disease, and therapeutic interventions

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7 January 2021

Treating activated CD4+ T cells with either of two distinct DNA methyltransferase inhibitors, 5-azacytidine or procainamide, is sufficient to cause a lupus-like disease in syngeneic mice

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7 January 2021

DNA methylation and autoimmune disease

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7 January 2021

Epigenetics and the Environment

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7 January 2021

Epigenetic transgenerational actions of endocrine disruptors and male fertility

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7 January 2021

Post-weaning diet affects genomic imprinting at the insulin-like growth factor 2 (Igf2) locus.

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7 January 2021

Transposable elements: targets for early nutritional effects on epigenetic gene regulation

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7 January 2021

Alcohol, one-carbon metabolism, and colorectal cancer: recent insights from molecular studies

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7 January 2021

Epigenetic programming by maternal behavior

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7 January 2021

Association of in vitro fertilization with Beckwith-Wiedemann syndrome and epigenetic alterations of LIT1 and H19

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7 January 2021

Epigenetics and assisted reproductive technology: a call for investigation

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7 January 2021

An integrated epigenetic and genetic approach to common human disease

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7 January 2021

Epigenetic differences arise during the lifetime of monozygotic twins

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7 January 2021

Hsp90 as a capacitor for morphological evolution

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7 January 2021

Evidence for an epigenetic mechanism by which Hsp90 acts as a capacitor for morphological evolution.

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7 January 2021

Systematic mapping of genetic interactions in Caenorhabditis elegans identifies common modifiers of diverse signaling pathways

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7 January 2021

The emerging science of epigenomics

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7 January 2021

Epigenetic cancer therapy makes headway

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7 January 2021

Selective HAT inhibitors as mechanistic tools for protein acetylation

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7 January 2021

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Histone deacetylase is a direct target of valproic acid, a potent anticonvulsant, mood stabilizer, and teratogen

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7 January 2021

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=17522677

Identifiers

2 references

30 April 2017

Consolidated OpenCitations Corpus – April 2017

Dimensions Publication ID

422190

1033770262

0 references

422190

1 reference

Consolidated OpenCitations Corpus – April 2017

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=17522677

2 references

30 April 2017

Consolidated OpenCitations Corpus – April 2017