Epidermal growth factor receptor (Q29525970)

Tyrosine protein kinase, EGF/ERB/XmrK receptor

1 reference

Growth factor receptor cysteine-rich domain superfamily

1 reference

Receptor L-domain superfamily

1 reference

Serine-threonine/tyrosine-protein kinase, catalytic domain, protein family

1 reference

Growth factor receptor domain 4, protein family

1 reference

Receptor L-domain, protein family

1 reference

Furin-like cysteine-rich domain, protein family

1 reference

Protein kinase domain, protein family

1 reference

Protein kinase, ATP binding site, protein family

1 reference

Tyrosine-protein kinase, catalytic domain, protein family

1 reference

Tyrosine-protein kinase, active site, protein family

1 reference

Furin-like repeat, protein family

1 reference

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QX70

1 reference

17 November 2021

1 reference

17 November 2021

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QX70

protein kinase activity

1 reference

14 February 2019

protein tyrosine kinase activity

transmembrane receptor protein tyrosine kinase activity

epidermal growth factor-activated receptor activity

4 references

14 February 2019

EGF receptor transactivation is obligatory for protein synthesis stimulation by G protein-coupled receptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QX70

14 February 2019

Transactivation of epidermal growth factor receptor mediates catecholamine-induced growth of vascular smooth muscle

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QX70

14 February 2019

Altered gene activity of epidermal growth factor receptor (ErbB-1) in the hypothalamus of aging female rat is linked to abnormal estrous cycles

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QX70

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QX70

signaling receptor binding

1 reference

14 February 2019

Integrin α(5) interacts with EGFR, is necessary for FcɛRI signaling and is necessary for allergic inflammation in relation with angiogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QX70

1 reference

14 February 2019

Integrin α(5) interacts with EGFR, is necessary for FcɛRI signaling and is necessary for allergic inflammation in relation with angiogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QX70

4 references

14 February 2019

A kinase cascade leading to Rab11-FIP5 controls transcytosis of the polymeric immunoglobulin receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QX70

14 February 2019

Integrin α(5) interacts with EGFR, is necessary for FcɛRI signaling and is necessary for allergic inflammation in relation with angiogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QX70

14 February 2019

Repetitive peroxide exposure reveals pleiotropic mitogen-activated protein kinase signaling mechanisms

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QX70

14 February 2019

Evidence for a functional role of Shc proteins in mitogenic signaling induced by insulin, insulin-like growth factor-1, and epidermal growth factor

GOA

curator

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QX70

1 reference

14 February 2019

The epidermal growth factor receptor tyrosine kinase phosphorylates connexin32

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QX70

2 references

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QX70

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QX70

A kinase cascade leading to Rab11-FIP5 controls transcytosis of the polymeric immunoglobulin receptor

protein kinase binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QX70

ubiquitin protein ligase binding

IPI

1 reference

14 February 2019

c-Cbl ubiquitin ligase regulates focal adhesion protein turnover and myofibril degeneration induced by neutrophil protease cathepsin G

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QX70

protein heterodimerization activity

IPI

1 reference

14 February 2019

The emergence of ErbB2 expression in cultured rat hepatocytes correlates with enhanced and diversified EGF-mediated signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QX70

1 reference

14 February 2019

The ErbB4 receptor in fetal rat lung fibroblasts and epithelial type II cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QX70

1 reference

14 February 2019

Endosomal signalling of epidermal growth factor receptors contributes to EGF-stimulated cell cycle progression in primary hepatocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QX70

1 reference

14 February 2019

Epidermal growth factor receptor distribution during chemotactic responses

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QX70

integral component of plasma membrane

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QX70

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

basal plasma membrane

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QX70

1 reference

14 February 2019

Integrin α(5) interacts with EGFR, is necessary for FcɛRI signaling and is necessary for allergic inflammation in relation with angiogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QX70

2 references

integral component of membrane

basolateral plasma membrane

2 references

1 reference

14 February 2019

Activation of the MEK5/ERK5 cascade is responsible for biliary dysgenesis in a rat model of Caroli's disease

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QX70

Activation of the MEK5/ERK5 cascade is responsible for biliary dysgenesis in a rat model of Caroli's disease

apical plasma membrane

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QX70

1 reference

14 February 2019

Epidermal growth factor receptor distribution during chemotactic responses

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QX70

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QX70

1 reference

14 February 2019

Sigma-1 receptors potentiate epidermal growth factor signaling towards neuritogenesis in PC12 cells: potential relation to lipid raft reconstitution

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QX70

1 reference

14 February 2019

Epidermal growth factor receptor in synaptic fractions of the rat central nervous system

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QX70

1 reference

14 February 2019

Evidence for a functional role of Shc proteins in mitogenic signaling induced by insulin, insulin-like growth factor-1, and epidermal growth factor

GOA

curator

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QX70

1 reference

14 February 2019

Diverse expression of ErbB receptor proteins during rat liver development and regeneration

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QX70

hair follicle development

1 reference

14 February 2019

Distribution of Epidermal Growth Factor Receptors in Rat Tissues During Embryonic Skin Development, Hair Formation, and the Adult Hair Growth Cycle

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QX70

1 reference

14 February 2019

EGF receptor transactivation is obligatory for protein synthesis stimulation by G protein-coupled receptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QX70

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QX70

protein phosphorylation

1 reference

14 February 2019

response to osmotic stress

1 reference

14 February 2019

Epidermal growth factor receptor mediates stress-induced expression of its ligands in rat gastric epithelial cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QX70

response to oxidative stress

1 reference

14 February 2019

Epidermal growth factor receptor mediates stress-induced expression of its ligands in rat gastric epithelial cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QX70

1 reference

14 February 2019

EGF receptor transactivation is obligatory for protein synthesis stimulation by G protein-coupled receptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QX70

epidermal growth factor receptor signaling pathway

1 reference

14 February 2019

Developmental regulation of epidermal growth factor receptor kinase in rat intestine

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QX70

1 reference

14 February 2019

Diverse expression of ErbB receptor proteins during rat liver development and regeneration

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QX70

positive regulation of cell population proliferation

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QX70

magnesium ion homeostasis

1 reference

14 February 2019

The EGFR tyrosine kinase inhibitor tyrphostin AG-1478 causes hypomagnesemia and cardiac dysfunction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QX70

response to organic cyclic compound

1 reference

14 February 2019

Theaflavins extracted from black tea inhibit airway mucous hypersecretion induced by cigarette smoke in rats

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QX70

diterpenoid metabolic process

1 reference

14 February 2019

Second-generation taxanes effectively suppress subcutaneous rat lymphoma: role of disposition, transport, metabolism, in vitro potency and expression of angiogenesis genes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QX70

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QX70

peptidyl-tyrosine phosphorylation

1 reference

14 February 2019

The epidermal growth factor receptor tyrosine kinase phosphorylates connexin32

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QX70

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QX70

1 reference

14 February 2019

Genetic influences on asthma susceptibility in the developing lung

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QX70

Regulation of epidermal growth factor receptor by estrogen

response to estradiol

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QX70

positive regulation of superoxide anion generation

1 reference

14 February 2019

Enhanced depolarization-induced pulmonary vasoconstriction following chronic hypoxia requires EGFR-dependent activation of NAD(P)H oxidase 2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QX70

Cobalamin deficiency-induced changes of epidermal growth factor (EGF)-receptor expression and EGF levels in rat spinal cord

response to cobalamin

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QX70

response to hydroxyisoflavone

1 reference

14 February 2019

Proteomic discovery of genistein action in the rat mammary gland

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QX70

1 reference

14 February 2019

Sphingosine 1-phosphate transactivates the platelet-derived growth factor beta receptor and epidermal growth factor receptor in vascular smooth muscle cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QX70

intracellular signal transduction

1 reference

14 February 2019

EGF receptor transactivation is obligatory for protein synthesis stimulation by G protein-coupled receptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QX70

1 reference

14 February 2019

Activation of epidermal growth factor receptor during corneal epithelial migration

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QX70

1 reference

14 February 2019

Altered gene activity of epidermal growth factor receptor (ErbB-1) in the hypothalamus of aging female rat is linked to abnormal estrous cycles

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QX70

hydrogen peroxide metabolic process

1 reference

14 February 2019

Repetitive peroxide exposure reveals pleiotropic mitogen-activated protein kinase signaling mechanisms

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QX70

1 reference

14 February 2019

Erb and c-Kit receptors have distinctive patterns of expression in adult and developing taste papillae and taste buds

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QX70

positive regulation of bone resorption

1 reference

14 February 2019

EGF receptor antiserum inhibits bone resorbing activity produced by a rat Leydig cell tumor associated with the humoral hypercalcemia of malignancy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QX70

positive regulation of vasoconstriction

1 reference

14 February 2019

Enhanced depolarization-induced pulmonary vasoconstriction following chronic hypoxia requires EGFR-dependent activation of NAD(P)H oxidase 2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QX70

negative regulation of mitotic cell cycle

1 reference

14 February 2019

Epidermal Growth Factor Induction of Phenotype-dependent Cell Cycle Arrest in Vascular Smooth Muscle Cells Is through the Mitogen-activated Protein Kinase Pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QX70

1 reference

14 February 2019

Epidermal growth factor receptor activation: an upstream signal for transition of quiescent astrocytes into reactive astrocytes after neural injury

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QX70

positive regulation of smooth muscle cell proliferation

1 reference

14 February 2019

Transactivation of epidermal growth factor receptor mediates catecholamine-induced growth of vascular smooth muscle

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QX70

neuron projection morphogenesis

1 reference

14 February 2019

Versican G3 domain regulates neurite growth and synaptic transmission of hippocampal neurons by activation of epidermal growth factor receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QX70

positive regulation of epithelial cell proliferation

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QX70

positive regulation of inflammatory response

1 reference

14 February 2019

Inhibition of EGFR/MAPK signaling reduces microglial inflammatory response and the associated secondary damage in rats after spinal cord injury

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QX70

Cross-talk between the calcium-sensing receptor and the epidermal growth factor receptor in Rat-1 fibroblasts

response to calcium ion

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QX70

positive regulation of synaptic transmission, glutamatergic

1 reference

14 February 2019

Versican G3 domain regulates neurite growth and synaptic transmission of hippocampal neurons by activation of epidermal growth factor receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QX70

cellular response to mechanical stimulus

1 reference

14 February 2019

Mechanical stretch potentiates angiotensin II-induced proliferation in spontaneously hypertensive rat vascular smooth muscle cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QX70

cellular response to growth factor stimulus

1 reference

14 February 2019

Long-term, heterologous down-regulation of the epidermal growth factor receptor in PC12 cells by nerve growth factor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QX70

cellular response to dexamethasone stimulus

1 reference

14 February 2019

Dexamethasone modulates ErbB tyrosine kinase expression and signaling through multiple and redundant mechanisms in cultured rat hepatocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QX70

1 reference

14 February 2019

Pretranslational and posttranslational regulation of the EGF receptor during the prereplicative phase of liver regeneration

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QX70

positive regulation of prolactin secretion

1 reference

14 February 2019

Monoclonal antibodies against epidermal growth factor receptor induce prolactin synthesis in cultured rat pituitary cells (GH3)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QX70

1 reference

protein kinase, ATP binding site

1 reference

serine-threonine/tyrosine-protein kinase, catalytic domain

1 reference

Growth factor receptor domain 4

1 reference

tyrosine-protein kinase, catalytic domain

1 reference

protein kinase domain

1 reference

tyrosine-protein kinase, active site

1 reference

Furin-like repeat

1 reference

Furin-like cysteine-rich domain

1 reference