Enhanced depolarization-induced pulmonary vasoconstriction following chronic hypoxia requires EGFR-dependent activation of NAD(P)H oxidase 2 (Q28582157)

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English	Enhanced depolarization-induced pulmonary vasoconstriction following chronic hypoxia requires EGFR-dependent activation of NAD(P)H oxidase 2	scientific journal article

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scholarly article

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31 January 2017

Europe PubMed Central

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12 February 2020

Enhanced depolarization-induced pulmonary vasoconstriction following chronic hypoxia requires EGFR-dependent activation of NAD(P)H oxidase 2 (English)

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31 January 2017

Europe PubMed Central

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12 February 2020

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vasoconstriction

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based on heuristic

inferred from title

3

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12 February 2020

Brad R S Broughton

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Brad R S Broughton

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12 February 2020

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Thomas C Resta

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12 February 2020

Benjimen R Walker

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Benjimen R Walker

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12 February 2020

author name string

Charles E Norton

1

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12 February 2020

publication date

18 October 2012

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12 February 2020

Antioxidants & Redox Signaling

2 references

31 January 2017

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12 February 2020

18

2 references

31 January 2017

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12 February 2020

1777-1788

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12 February 2020

14

2 references

31 January 2017

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22966991%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Metabotropic regulation of RhoA/Rho-associated kinase by L-type Ca2+ channels: new mechanism for depolarization-evoked mammalian arterial contraction

1 reference

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17 March 2017

Differential effects of chronic hypoxia and intermittent hypocapnic and eucapnic hypoxia on pulmonary vasoreactivity

1 reference

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17 March 2017

Vasoconstrictor effect of endothelin-1 on hypertensive pulmonary arterial smooth muscle involves Rho-kinase and protein kinase C

1 reference

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17 March 2017

Decreased blood pressure in NOX1-deficient mice

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17 March 2017

Nox1 is involved in angiotensin II-mediated hypertension: a study in Nox1-deficient mice

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17 March 2017

Hierarchy of binding sites for Grb2 and Shc on the epidermal growth factor receptor

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17 March 2017

Chronic hypoxia upregulates pulmonary arterial ASIC1: a novel mechanism of enhanced store-operated Ca2+ entry and receptor-dependent vasoconstriction

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29 September 2017

Membrane depolarization is the trigger for PI3K/Akt activation and leads to the generation of ROS.

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29 September 2017

NFATc3 is required for chronic hypoxia-induced pulmonary hypertension in adult and neonatal mice

1 reference

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29 September 2017

Intermittent hypoxia augments pulmonary vascular smooth muscle reactivity to NO: regulation by reactive oxygen species

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29 September 2017

NADPH oxidase pathway is involved in aortic contraction induced by A3 adenosine receptor in mice.

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29 September 2017

Nox2 B-loop peptide, Nox2ds, specifically inhibits the NADPH oxidase Nox2

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29 September 2017

The epidermal growth factor receptor mediates tumor necrosis factor-alpha-induced activation of the ERK/GEF-H1/RhoA pathway in tubular epithelium

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NADPH oxidase-derived reactive oxygen species: involvement in vascular physiology and pathology

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29 September 2017

Activation of NAD(P)H oxidases by thromboxane A2 receptor uncouples endothelial nitric oxide synthase.

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29 September 2017

PPAR{gamma} regulates hypoxia-induced Nox4 expression in human pulmonary artery smooth muscle cells through NF-{kappa}B.

1 reference

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29 September 2017

Kinetics of PIP2 metabolism and KCNQ2/3 channel regulation studied with a voltage-sensitive phosphatase in living cells

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29 September 2017

GTPase-Rac enhances depolarization-induced superoxide production by the macula densa during tubuloglomerular feedback

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29 September 2017

Chronic hypoxia augments depolarization-induced Ca2+ sensitization in pulmonary vascular smooth muscle through superoxide-dependent stimulation of RhoA.

1 reference

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29 September 2017

Mechanisms of intermittent hypoxia induced hypertension

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29 September 2017

Vascular smooth muscle modulates endothelial control of vasoreactivity via reactive oxygen species production through myoendothelial communications.

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29 September 2017

NADPH oxidases and reactive oxygen species at different stages of chronic hypoxia-induced pulmonary hypertension in newborn piglets

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29 September 2017

Membrane depolarization causes a direct activation of G protein-coupled receptors leading to local Ca2+ release in smooth muscle

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29 September 2017

Rosiglitazone attenuates chronic hypoxia-induced pulmonary hypertension in a mouse model

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29 September 2017

Ci-VSP is a depolarization-activated phosphatidylinositol-4,5-bisphosphate and phosphatidylinositol-3,4,5-trisphosphate 5'-phosphatase

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29 September 2017

NOX4 mediates hypoxia-induced proliferation of human pulmonary artery smooth muscle cells: the role of autocrine production of transforming growth factor-{beta}1 and insulin-like growth factor binding protein-3.

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29 September 2017

The role of NADPH oxidase in chronic intermittent hypoxia-induced pulmonary hypertension in mice

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29 September 2017

Reactive oxygen species from NADPH oxidase contribute to altered pulmonary vascular responses in piglets with chronic hypoxia-induced pulmonary hypertension

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29 September 2017

Reactive oxygen species mediate RhoA/Rho kinase-induced Ca2+ sensitization in pulmonary vascular smooth muscle following chronic hypoxia

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Lung EC-SOD overexpression attenuates hypoxic induction of Egr-1 and chronic hypoxic pulmonary vascular remodeling

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29 September 2017

Zipper-interacting protein kinase induces Ca(2+)-free smooth muscle contraction via myosin light chain phosphorylation

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29 September 2017

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Chronic hypoxia induces Rho kinase-dependent myogenic tone in small pulmonary arteries

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3 June 2018

Hypoxia inducible factor 1 mediates hypoxia-induced TRPC expression and elevated intracellular Ca2+ in pulmonary arterial smooth muscle cells

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3 June 2018

Chronic hypoxia-induced upregulation of store-operated and receptor-operated Ca2+ channels in pulmonary arterial smooth muscle cells: a novel mechanism of hypoxic pulmonary hypertension

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3 June 2018

Rho/Rho kinase signaling mediates increased basal pulmonary vascular tone in chronically hypoxic rats

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3 June 2018

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3 June 2018

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Oxidative stress and endothelial dysfunction in aortas of aged spontaneously hypertensive rats by NOX1/2 is reversed by NADPH oxidase inhibition

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27 November 2018

Mechanical strain-induced RhoA activation requires NADPH oxidase-mediated ROS generation in caveolae

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27 November 2018

Direct voltage control of endogenous lysophosphatidic acid G-protein-coupled receptors in Xenopus oocytes.

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27 November 2018

Superoxide constricts rat pulmonary arteries via Rho-kinase-mediated Ca(2+) sensitization.

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27 November 2018

Depolarization activates the phosphoinositide phosphatase Ci-VSP, as detected in Xenopus oocytes coexpressing sensors of PIP2.

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27 November 2018

Hypoxia-dependent regulation of nonphagocytic NADPH oxidase subunit NOX4 in the pulmonary vasculature.

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27 November 2018

Hydrogen peroxide-induced Ca2+ mobilization in pulmonary arterial smooth muscle cells.

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27 November 2018

Role of reactive oxygen species and gp91phox in endothelial dysfunction of pulmonary arteries induced by chronic hypoxia

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27 November 2018

Mechanisms of endothelin-1-induced contraction in pulmonary arteries from chronically hypoxic rats

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27 November 2018

Hypoxic pulmonary hypertension: role of superoxide and NADPH oxidase (gp91phox).

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27 November 2018

Epidermal growth factor receptor blockade mediates smooth muscle cell apoptosis and improves survival in rats with pulmonary hypertension

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27 November 2018

Membrane depolarization and NADPH oxidase activation in aortic endothelium during ischemia reflect altered mechanotransduction

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27 November 2018

Endothelium-derived reactive oxygen species and endothelin-1 attenuate NO-dependent pulmonary vasodilation following chronic hypoxia

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27 November 2018

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27 November 2018

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27 November 2018

Novel competitive inhibitor of NAD(P)H oxidase assembly attenuates vascular O(2)(-) and systolic blood pressure in mice.

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27 November 2018

Estradiol-induced attenuation of pulmonary hypertension is not associated with altered eNOS expression

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27 November 2018

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27 November 2018

Characteristics of the inhibition of NADPH oxidase activation in neutrophils by apocynin, a methoxy-substituted catechol

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12 December 2020

based on heuristic

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Chronic hypoxia selectively augments endothelium-dependent pulmonary arterial vasodilation

1 reference

https://pubmed.ncbi.nlm.nih.gov/22966991

12 December 2020

based on heuristic

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Critical role of calcium- dependent epidermal growth factor receptor transactivation in PC12 cell membrane depolarization and bradykinin signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/22966991

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Depolarization of the macula densa induces superoxide production via NAD(P)H oxidase

1 reference

https://pubmed.ncbi.nlm.nih.gov/22966991

12 December 2020

based on heuristic

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The small G-protein Rac mediates depolarization-induced superoxide formation in human endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22966991

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1089/ARS.2012.4836

2 references

31 January 2017

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22966991%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22966991%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

2 references

31 January 2017

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22966991%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

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