Inhibition of Nonsense-mediated mRNA Decay by the Natural Product Pateamine A through Eukaryotic Initiation Factor 4AIII (Q29028235)

natural product chemistry

25 March 2017

1 reference

1 reference

1

Y. Dang

1 reference

25 March 2017

author name string

W.-K. Low

2

1 reference

25 March 2017

J. Xu

3

1 reference

25 March 2017

N. H. Gehring

4

1 reference

25 March 2017

H. C. Dietz

5

1 reference

25 March 2017

D. Romo

6

1 reference

25 March 2017

J. O. Liu

7

1 reference

25 March 2017

language of work or name

English

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publication date

1 July 2009

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25 March 2017

number of pages

9

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Journal of Biological Chemistry

inferred from page(s)

published in

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25 March 2017

volume

284

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25 March 2017

page(s)

23613-23621

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25 March 2017

issue

35

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describes a project that uses

25 March 2017

ImageJ

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2749136/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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Distant N- and C-terminal domains are required for intrinsic kinase activity of SMG-1, a critical component of nonsense-mediated mRNA decay

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Mutational analysis of human eIF4AIII identifies regions necessary for exon junction complex formation and nonsense-mediated mRNA decay

26 March 2017

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Binding of a novel SMG-1-Upf1-eRF1-eRF3 complex (SURF) to the exon junction complex triggers Upf1 phosphorylation and nonsense-mediated mRNA decay

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A nuclear translation-like factor eIF4AIII is recruited to the mRNA during splicing and functions in nonsense-mediated decay

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26 March 2017

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Phosphorylation of hUPF1 induces formation of mRNA surveillance complexes containing hSMG-5 and hSMG-7

26 March 2017

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Human SMG-1, a novel phosphatidylinositol 3-kinase-related protein kinase, associates with components of the mRNA surveillance complex and is involved in the regulation of nonsense-mediated mRNA decay

26 March 2017

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26 March 2017

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Evidence that phosphorylation of human Upfl protein varies with intracellular location and is mediated by a wortmannin-sensitive and rapamycin-sensitive PI 3-kinase-related kinase signaling pathway

26 March 2017

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26 March 2017

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Communication with the exon-junction complex and activation of nonsense-mediated decay by human Upf proteins occur in the cytoplasm.

3 June 2018

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3 June 2018

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3 June 2018

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3 June 2018

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Internal ribosome entry sequence-mediated translation initiation triggers nonsense-mediated decay

3 June 2018

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3 June 2018

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3 June 2018

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Takeover of host ribosomes by divergent IRES elements.

3 June 2018

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Messenger RNA surveillance: neutralizing natural nonsense

3 June 2018

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Smg1 nonsense mutations do not abolish nonsense-mediated mRNA decay in Drosophila melanogaster

3 June 2018

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3 June 2018

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A new function for nonsense-mediated mRNA-decay factors

3 June 2018

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SMG-1 is a phosphatidylinositol kinase-related protein kinase required for nonsense-mediated mRNA Decay in Caenorhabditis elegans

3 June 2018

1 reference

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eIF4AIII binds spliced mRNA in the exon junction complex and is essential for nonsense-mediated decay

3 June 2018

1 reference

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New insights into the formation of active nonsense-mediated decay complexes.

3 June 2018

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3 June 2018

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3 June 2018

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3 June 2018

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A regulatory mechanism that detects premature nonsense codons in T-cell receptor transcripts in vivo is reversed by protein synthesis inhibitors in vitro

3 June 2018

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3 June 2018

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hUPF2 silencing identifies physiologic substrates of mammalian nonsense-mediated mRNA decay

21 January 2018

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Making structural sense of nonsense-mediated decay.

21 January 2018

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Specific inhibition of nonsense-mediated mRNA decay components, SMG-1 or Upf1, rescues the phenotype of ullrich disease fibroblasts

21 January 2018

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No mercy for messages that mess with the ribosome

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12 December 2020

The three-dimensional arcitecture of the EJC core

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12 December 2020

Peloruside A: a potent cytotoxic macrolide isolated from the new zealand marine sponge Mycale sp

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A quality control pathway that down-regulates aberrant T-cell receptor (TCR) transcripts by a mechanism requiring UPF2 and translation

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Identifiers

DOI

10.1074/JBC.M109.009985

1 reference