Structural characterization of partially disordered human Chibby: insights into its function in the Wnt-signaling pathway (Q28910332)

protein homotetramerization

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author name string

Sulayman Mokhtarzada

1

1 reference

7 March 2017

Corey Yu

2

1 reference

7 March 2017

Anne Brickenden

3

1 reference

7 March 2017

Wing-Yiu Choy

Nuclear-cytoplasmic shuttling of Chibby controls beta-catenin signaling.

4

1 reference

7 March 2017

language of work or name

English

0 references

publication date

8 February 2011

1 reference

7 March 2017

1 reference

7 March 2017

50

1 reference

7 March 2017

715–726

1 reference

7 March 2017

5

1 reference

7 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031990

Inactivation of Chibby affects function of motile airway cilia

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031990

Chibby cooperates with 14-3-3 to regulate beta-catenin subcellular distribution and signaling activity

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031990

Intrinsically disordered human C/EBP homologous protein regulates biological activity of colon cancer cells during calcium stress

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031990

Crystal Structure of a Full-Length β-Catenin

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031990

Chibby promotes adipocyte differentiation through inhibition of beta-catenin signaling

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031990

Chibby, an antagonist of the Wnt/beta-catenin pathway, facilitates cardiomyocyte differentiation of murine embryonic stem cells

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031990

beta-catenin destruction complex: insights and questions from a structural perspective

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031990

Wnt/beta-catenin signaling in development and disease

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031990

The C/EBP homologous protein CHOP (GADD153) is an inhibitor of Wnt/TCF signals

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031990

TC1 (C8orf4) enhances the Wnt/beta-catenin pathway by relieving antagonistic activity of Chibby

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031990

Intrinsically unstructured proteins and their functions

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031990

The Wnt signaling pathway in development and disease

16 March 2017

1 reference

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Using NMRView to visualize and analyze the NMR spectra of macromolecules

16 March 2017

1 reference

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PIGEA-14, a novel coiled-coil protein affecting the intracellular distribution of polycystin-2

16 March 2017

1 reference

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TC-1 is a novel tumorigenic and natively disordered protein associated with thyroid cancer

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031990

Chibby, a nuclear beta-catenin-associated antagonist of the Wnt/Wingless pathway

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031990

ICAT inhibits beta-catenin binding to Tcf/Lef-family transcription factors and the general coactivator p300 using independent structural modules

16 March 2017

1 reference

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The crystal structure of the beta-catenin/ICAT complex reveals the inhibitory mechanism of ICAT

16 March 2017

1 reference

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Probability-based protein secondary structure identification using combined NMR chemical-shift data

16 March 2017

1 reference

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Structure of a human Tcf4-beta-catenin complex

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031990

Tcf4 can specifically recognize beta-catenin using alternative conformations

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031990

Molecular mechanisms of beta-catenin recognition by adenomatous polyposis coli revealed by the structure of an APC-beta-catenin complex

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031990

The structure of the beta-catenin/E-cadherin complex and the molecular basis of diverse ligand recognition by beta-catenin

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031990

Crystal structure of a beta-catenin/Tcf complex

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031990

Cloning of TC-1 (C8orf4), a novel gene found to be overexpressed in thyroid cancer

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031990

16 March 2017

Wnt signaling and cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031990

Attenuated T2 relaxation by mutual cancellation of dipole-dipole coupling and chemical shift anisotropy indicates an avenue to NMR structures of very large biological macromolecules in solution

16 March 2017

1 reference

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Three-dimensional structure of the armadillo repeat region of beta-catenin

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031990

Functional interaction of beta-catenin with the transcription factor LEF-1

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031990

Interaction of 14-3-3 with signaling proteins is mediated by the recognition of phosphoserine

16 March 2017

1 reference

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NMRPipe: a multidimensional spectral processing system based on UNIX pipes

16 March 2017

1 reference

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The 13C chemical-shift index: a simple method for the identification of protein secondary structure using 13C chemical-shift data

16 March 2017

1 reference

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Backbone dynamics of a free and phosphopeptide-complexed Src homology 2 domain studied by 15N NMR relaxation

16 March 2017

1 reference

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The structural basis for 14-3-3:phosphopeptide binding specificity

16 March 2017

1 reference

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beta-catenin is a target for the ubiquitin-proteasome pathway

7 April 2017

1 reference

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WNT and beta-catenin signalling: diseases and therapies

7 April 2017

1 reference

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Natively unfolded proteins: a point where biology waits for physics

7 April 2017

1 reference

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Coupling of folding and binding for unstructured proteins

7 April 2017

1 reference

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Estimation of protein secondary structure from circular dichroism spectra: comparison of CONTIN, SELCON, and CDSSTR methods with an expanded reference set

7 April 2017

1 reference

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Sequence complexity of disordered protein

7 April 2017

1 reference

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Why are "natively unfolded" proteins unstructured under physiologic conditions?

7 April 2017

1 reference

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Prediction and analysis of coiled-coil structures

7 April 2017

1 reference

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Chibby interacts with NBPF1 and clusterin, two candidate tumor suppressors linked to neuroblastoma

7 April 2017

1 reference

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Unfoldomics of human diseases: linking protein intrinsic disorder with diseases

3 June 2018

1 reference

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Protein dynamics and conformational disorder in molecular recognition

3 June 2018

1 reference

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Chibby forms a homodimer through a heptad repeat of leucine residues in its C-terminal coiled-coil motif

3 June 2018

1 reference

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Fine-tuning of nuclear-catenin by Chibby and 14-3-3

3 June 2018

1 reference

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Linking folding and binding

3 June 2018

1 reference

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Large-scale analysis of thermostable, mammalian proteins provides insights into the intrinsically disordered proteome

3 June 2018

1 reference

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Evidence for a coiled-coil interaction mode of disordered proteins from bacterial type III secretion systems

3 June 2018

1 reference

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The intrinsically disordered TC-1 interacts with Chibby via regions with high helical propensity

3 June 2018

1 reference

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Wnt signaling as a therapeutic target for cancer

3 June 2018

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3 June 2018

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3 June 2018

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Reduced expression of beta-catenin inhibitor Chibby in colon carcinoma cell lines.

3 June 2018

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3 June 2018

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3 June 2018

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3 June 2018

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3 June 2018

1 reference

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Buried asparagines determine the dimerization specificities of leucine zipper mutants

3 June 2018

1 reference

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3 June 2018

1 reference

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Chemical shifts as a tool for structure determination

3 June 2018

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Two-state conformational equilibrium in the Par-4 leucine zipper domain.

3 June 2018

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26 November 2018

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26 November 2018

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Dynein light chain LC8 is a dimerization hub essential in diverse protein networks.

26 November 2018

1 reference

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26 November 2018

1 reference

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Preformed structural elements feature in partner recognition by intrinsically unstructured proteins.

26 November 2018

1 reference

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12 December 2020

Signal response of coexisting protein conformers in electrospray mass spectrometry

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Heteronuclear NMR identifies a nascent helix in intrinsically disordered dynein intermediate chain: implications for folding and dimerization

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Predicting Protein Disorder for N-, C-, and Internal Regions

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12 December 2020