Fold stability during endolysosomal acidification is a key factor for allergenicity and immunogenicity of the major birch pollen allergen (Q28833624)

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29 February 2020

title

Fold stability during endolysosomal acidification is a key factor for allergenicity and immunogenicity of the major birch pollen allergen (English)

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29 February 2020

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1

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Regina Freier

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Arthur Hinterholzer

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Markus Steiner

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Jutta Horejs-Hoeck

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Fatima Ferreira

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Klaus R. Liedl

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P Lackner

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Hans Brandstetter

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Richard Weiss

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Peter Briza

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ORCID Public Data File 2021

author name string

Sandra Scheiblhofer

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Theresa Thalhamer

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Melissa Mayr

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Sarina Grutsch

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Linda Ahammer

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Julian E Fuchs

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Hannes G Wallnoefer

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Almedina Isakovic

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Vera Kohlbauer

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Martin Danzer

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Martin Tollinger

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Christopher M Johnson

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Josef Thalhamer

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language of work or name

English

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publication date

11 November 2015

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number of pages

10

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The Journal of Allergy and Clinical Immunology

inferred from page(s)

published in

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volume

137

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issue

5

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page(s)

1525-1534

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Crystallographically Mapped Ligand Binding Differs in High and Low IgE Binding Isoforms of Birch Pollen Allergen Bet v 1

29 February 2020

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1 reference

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Assessing protein immunogenicity with a dendritic cell line-derived endolysosomal degradome

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X-ray and NMR structure of Bet v 1, the origin of birch pollen allergy

16 March 2017

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Correlation of sensitizing capacity and T-cell recognition within the Bet v 1 family.

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Ligand binding modulates the structural dynamics and compactness of the major birch pollen allergen.

3 June 2018

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Intrinsic flexibility of NLRP pyrin domains is a key factor in their conformational dynamics, fold stability, and dimerization

3 June 2018

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Bet v 1--a Trojan horse for small ligands boosting allergic sensitization?

3 June 2018

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Bet v 1 from birch pollen is a lipocalin-like protein acting as allergen only when devoid of iron by promoting Th2 lymphocytes.

3 June 2018

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Chimeras of Bet v 1 and Api g 1 reveal heterogeneous IgE responses in patients with birch pollen allergy

3 June 2018

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Generation of hypoallergenic neoglycoconjugates for dendritic cell targeted vaccination: a novel tool for specific immunotherapy

3 June 2018

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3 June 2018

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A recombinant immunotoxin engineered for increased stability by adding a disulfide bond has decreased immunogenicity.

3 June 2018

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Naturally processed T cell-activating peptides of the major birch pollen allergen.

3 June 2018

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New insights into innate immune mechanisms underlying allergenicity

3 June 2018

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Antigen aggregation decides the fate of the allergic immune response

3 June 2018

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Identification of B-cell epitopes of Bet v 1 involved in cross-reactivity with food allergens

3 June 2018

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Determinants of allergenicity

3 June 2018

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3 June 2018

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3 June 2018

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3 June 2018

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3 June 2018

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3 June 2018

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3 June 2018

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3 June 2018

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Modulation of the allergic immune response in BALB/c mice by subcutaneous injection of high doses of the dominant T cell epitope from the major birch pollen allergen Bet v 1.

3 June 2018

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26 November 2018

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26 November 2018

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26 November 2018

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26 November 2018

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26 November 2018

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Antigen stability controls antigen presentation

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10.1016/J.JACI.2015.09.026

Identifiers

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