Novel sterol metabolic network of Trypanosoma brucei procyclic and bloodstream forms (Q28714212)

2

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Jialin Liu

3

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Kulothungan Ganapathy

4

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Fernando Villalta

5

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Michael R Waterman

6

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Galina I Lepesheva

7

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Minu Chaudhuri

8

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W David Nes

Biosynthesis of cholesterol and other sterols

9

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language of work or name

English

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publication date

1 April 2012

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published in

Biochemical Journal

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volume

443

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page(s)

267-77

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issue

1

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cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491665

Microaerobic steroid biosynthesis and the molecular fossil record of Archean life

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491665

Substrate Preferences and Catalytic Parameters Determined by Structural Characteristics of Sterol 14α-Demethylase (CYP51) from Leishmania infantum

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491665

Rewiring and regulation of cross-compartmentalized metabolism in protists

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491665

Crystal structures of Trypanosoma brucei sterol 14alpha-demethylase and implications for selective treatment of human infections

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491665

Sterols in a unicellular relative of the metazoans

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491665

Sterol methyltransferase 1 controls the level of cholesterol in plants

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491665

High-throughput phenotyping using parallel sequencing of RNA interference targets in the African trypanosome

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491665

Lipid metabolism in Trypanosoma brucei

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491665

Sterol regulatory element binding proteins in fungi: hypoxic transcription factors linked to pathogenesis

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491665

Sterol Biosynthesis Pathway as Target for Anti-trypanosomatid Drugs

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491665

Acetate produced in the mitochondrion is the essential precursor for lipid biosynthesis in procyclic trypanosomes

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491665

Sterol 14-demethylase inhibitors for Trypanosoma cruzi infections.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491665

Sterol 14alpha-demethylase as a potential target for antitrypanosomal therapy: enzyme inhibition and parasite cell growth

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491665

The non-mevalonate pathway of isoprenoid precursor biosynthesis.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491665

New azasterols against Trypanosoma brucei: role of 24-sterol methyltransferase in inhibitor action.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491665

Chemotherapy of trypanosomiases and leishmaniasis

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491665

Isoprenoid biosynthesis in the diatoms Rhizosolenia setigera (Brightwell) and Haslea ostrearia (Simonsen).

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491665

Oxidosqualene cyclase inhibitors as antimicrobial agents.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491665

Fatty acid and sterol metabolism: potential antimicrobial targets in apicomplexan and trypanosomatid parasitic protozoa

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491665

Secondary loss of chloroplasts in trypanosomes

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491665

The biosynthetic incorporation of the intact leucine skeleton into sterol by the trypanosomatid Leishmania mexicana.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491665

The adaptative mechanisms of Trypanosoma brucei for sterol homeostasis in its different life-cycle environments

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491665

Elucidation of carbon sources used for the biosynthesis of fatty acids and sterols in the trypanosomatid Leishmania mexicana

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491665

The lipid metabolism of blood and culture forms of Trypanosoma lewisi and Trypanosoma rhodesiense

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491665

Multiple functions for sterols in Saccharomyces cerevisiae.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491665

Sterols of parasitic protozoa and helminths

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491665

Sterols, toxins and parasitism

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491665

CYP51 from Trypanosoma brucei is obtusifoliol-specific

3 June 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111849

Mechanistic analysis of a multiple product sterol methyltransferase implicated in ergosterol biosynthesis in Trypanosoma brucei

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111849

Cholesterol import fails to prevent catalyst-based inhibition of ergosterol synthesis and cell proliferation of Trypanosoma brucei.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111849

Protist phylogeny and the high-level classification of Protozoa

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111849

Cloning and heterologous expression of the Trypanosoma brucei lanosterol synthase gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111849

Glucose-induced remodeling of intermediary and energy metabolism in procyclic Trypanosoma brucei

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111849

Enzyme redesign and interactions of substrate analogues with sterol methyltransferase to understand phytosterol diversity, reaction mechanism and the nature of the active site

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111849

Utilization of leucine and acetate as carbon sources for sterol and fatty acid biosynthesis by Old and New World Leishmania species, Endotrypanum monterogeii and Trypanosoma cruzi

21 January 2018

2 references

https://api.crossref.org/works/10.1042%2FBJ20111849

21 January 2018

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491665

Effect of substrate features and mutagenesis of active site tyrosine residues on the reaction course catalysed by Trypanosoma brucei sterol C-24-methyltransferase

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22176028

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Exogenous and endogenous sources of sterols in the culture-adapted procyclic trypomastigotes of Trypanosoma brucei

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22176028

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Trypanosome sterols and their metabolic origins

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22176028