The non-mevalonate pathway of isoprenoid precursor biosynthesis. (Q36795133)

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29 December 2019

review article

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title

The non-mevalonate pathway of isoprenoid precursor biosynthesis (English)

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29 December 2019

1

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author name string

William N Hunter

series ordinal

1

1 reference

16 August 2017

language of work or name

English

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publication date

18 April 2007

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Journal of Biological Chemistry

29 December 2019

published in

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29 December 2019

volume

282

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29 December 2019

page(s)

21573-21577

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29 December 2019

issue

30

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Diversity of the biosynthesis of the isoprene units

29 December 2019

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Elucidation of the methylerythritol phosphate pathway for isoprenoid biosynthesis in bacteria and plastids. A metabolic milestone achieved through genomics.

21 January 2018

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The discovery of a mevalonate-independent pathway for isoprenoid biosynthesis in bacteria, algae and higher plants

21 January 2018

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Crystal structure of 1-deoxy-D-xylulose 5-phosphate synthase, a crucial enzyme for isoprenoids biosynthesis.

21 January 2018

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Snapshot of a key intermediate in enzymatic thiamin catalysis: crystal structure of the alpha-carbanion of (alpha,beta-dihydroxyethyl)-thiamin diphosphate in the active site of transketolase from Saccharomyces cerevisiae

21 January 2018

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1-Deoxy-D-xylulose 5-phosphate reductoisomerase: an overview

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Inhibitors of the nonmevalonate pathway of isoprenoid biosynthesis as antimalarial drugs

21 January 2018

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Crystal structure of 1-deoxy-D-xylulose 5-phosphate reductoisomerase complexed with cofactors: implications of a flexible loop movement upon substrate binding

21 January 2018

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Crystal structure of 1-deoxy-D-xylulose-5-phosphate reductoisomerase, a crucial enzyme in the non-mevalonate pathway of isoprenoid biosynthesis

21 January 2018

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Structural basis of fosmidomycin action revealed by the complex with 2-C-methyl-D-erythritol 4-phosphate synthase (IspC). Implications for the catalytic mechanism and anti-malaria drug development

21 January 2018

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The crystal structure of E.coli 1-deoxy-D-xylulose-5-phosphate reductoisomerase in a ternary complex with the antimalarial compound fosmidomycin and NADPH reveals a tight-binding closed enzyme conformation

21 January 2018

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Crystallographic structures of two bisphosphonate:1-deoxyxylulose-5-phosphate reductoisomerase complexes

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Crystal structure of 1-deoxy-d-xylulose-5-phosphate reductoisomerase from Zymomonas mobilis at 1.9-A resolution

21 January 2018

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The 1.9 A resolution structure of Mycobacterium tuberculosis 1-deoxy-D-xylulose 5-phosphate reductoisomerase, a potential drug target

21 January 2018

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Structure of 4-diphosphocytidyl-2-C- methylerythritol synthetase involved in mevalonate- independent isoprenoid biosynthesis

21 January 2018

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Kinetic analysis of Escherichia coli 2-C-methyl-D-erythritol-4-phosphate cytidyltransferase, wild type and mutants, reveals roles of active site amino acids

21 January 2018

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The crystal structure of a plant 2C-methyl-D-erythritol 4-phosphate cytidylyltransferase exhibits a distinct quaternary structure compared to bacterial homologues and a possible role in feedback regulation for cytidine monophosphate.

21 January 2018

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Hexameric assembly of the bifunctional methylerythritol 2,4-cyclodiphosphate synthase and protein-protein associations in the deoxy-xylulose-dependent pathway of isoprenoid precursor biosynthesis

21 January 2018

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Biosynthesis of isoprenoids: Crystal structure of 4-diphosphocytidyl-2C-methyl-D-erythritol kinase

21 January 2018

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Crystal structure of 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase, an enzyme in the non-mevalonate pathway of isoprenoid synthesis

21 January 2018

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Structure of 2C-methyl-D-erythritol 2,4- cyclodiphosphate synthase: an essential enzyme for isoprenoid biosynthesis and target for antimicrobial drug development

21 January 2018

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Structure of 2C-methyl-d-erythritol-2,4-cyclodiphosphate synthase involved in mevalonate-independent biosynthesis of isoprenoids

21 January 2018

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Structure and mechanism of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase. An enzyme in the mevalonate-independent isoprenoid biosynthetic pathway

21 January 2018

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Structure of 2C-methyl-D-erythritol-2,4-cyclodiphosphate synthase from Shewanella oneidensis at 1.6 A: identification of farnesyl pyrophosphate trapped in a hydrophobic cavity

21 January 2018

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Perspectives in anti-infective drug design. The late steps in the biosynthesis of the universal terpenoid precursors, isopentenyl diphosphate and dimethylallyl diphosphate

21 January 2018

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fldA is an essential gene required in the 2-C-methyl-D-erythritol 4-phosphate pathway for isoprenoid biosynthesis.

21 January 2018

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Crystal structure of isopentenyl diphosphate:dimethylallyl diphosphate isomerase

21 January 2018

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Catalytic mechanism of Escherichia coli isopentenyl diphosphate isomerase involves Cys-67, Glu-116, and Tyr-104 as suggested by crystal structures of complexes with transition state analogues and irreversible inhibitors

21 January 2018

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Crystal structures of human IPP isomerase: new insights into the catalytic mechanism

21 January 2018

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Crystal structure of the type II isopentenyl diphosphate:dimethylallyl diphosphate isomerase from Bacillus subtilis

21 January 2018

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Structure of Thermus thermophilus type 2 isopentenyl diphosphate isomerase inferred from crystallography and molecular dynamics.

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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The methylerythritol phosphate pathway is functionally active in all intraerythrocytic stages of Plasmodium falciparum

21 January 2018

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21 January 2018

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Identifiers

DOI

10.1074/JBC.R700005200

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17442674%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

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