Non-physiological amino acid (NPAA) therapy targeting brain phenylalanine reduction: pilot studies in PAHENU2 mice (Q28703649)

2

0 references

Brandi L Wasek

3

0 references

Teodoro Bottiglieri

4

0 references

K Michael Gibson

Journal of Inherited Metabolic Disease

5

0 references

language of work or name

English

0 references

publication date

May 2013

0 references

published in

0 references

volume

36

0 references

page(s)

513-23

0 references

issue

3

0 references

exact match

https://scigraph.springernature.com/pub.10.1007/s10545-012-9524-8

0 references

cites work

Identification of LAT4, a novel amino acid transporter with system L activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3654543

Identification of a novel system L amino acid transporter structurally distinct from heterodimeric amino acid transporters

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3654543

Large neutral amino acids block phenylalanine transport into brain tissue in patients with phenylketonuria

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3654543

Expression cloning and characterization of a transporter for large neutral amino acids activated by the heavy chain of 4F2 antigen (CD98)

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3654543

Role of serotonin in Alzheimer's disease: a new therapeutic target?

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3654543

The monoamine neurotransmitter disorders: an expanding range of neurological syndromes

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3654543

Large neutral amino acids in the treatment of PKU: from theory to practice

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3654543

Suboptimal outcomes in patients with PKU treated early with diet alone: revisiting the evidence

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3654543

Future treatment strategies in phenylketonuria

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3654543

Hepatocyte transplantation (HTx) corrects selected neurometabolic abnormalities in murine intermediate maple syrup urine disease (iMSUD).

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3654543

Dual mechanism of brain injury and novel treatment strategy in maple syrup urine disease

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3654543

LAT-1 expression in pre- and post-implantation embryos and placenta

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3654543

Response of phenylketonuria to tetrahydrobiopterin

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3654543

Large neutral amino acids in the treatment of phenylketonuria (PKU).

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3654543

Prostaglandin J2 reduces catechol-O-methyltransferase activity and enhances dopamine toxicity in neuronal cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3654543

L-type amino acid transporter-1 overexpression and melphalan sensitivity in Barrett's adenocarcinoma

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3654543

BACTERIAL METABOLISM OF 2-METHYLALANINE

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3654543

Transfer of glutamine between astrocytes and neurons

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3654543

Transport of methionine and proline by rat liver slices and the effect of certain hormones

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3654543

Phenylalanine transport at the human blood-brain barrier. Studies with isolated human brain capillaries.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3654543

Kinetics of neutral amino acid transport across the blood-brain barrier.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3654543

Candida L-norleucine,leucine:2-oxoglutarate aminotransferase. Purification and properties

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3654543

Tissue amino acids in rats fed norleucine, norvaline, homoarginine or other amino acid analogues.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3654543

Role of amino acid transport and countertransport in nutrition and metabolism

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3654543

Norleucine: a branched-chain amino acid analog affecting feeding behavior of rats.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3654543

Branched-chain and other amino acids in tissues of rats fed leucine-limiting amino acid diets containing norleucine.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3654543

Transport of alpha-aminoisobutyric acid across the blood-brain barrier studied with in situ perfusion of rat brain.

20 June 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-012-9524-8

β-Cell-protective effect of 2-aminobicyclo-(2,2,1)-heptane-2-carboxylic acid as a glutamate dehydrogenase activator in db/db mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-012-9524-8

The influence of high phenylalanine and tyrosine on the concentrations of essential amino acids in brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-012-9524-8

Identification and functional characterization of a Na+-independent neutral amino acid transporter with broad substrate selectivity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-012-9524-8

Blood-brain barrier transport of amino acids in healthy controls and in patients with phenylketonuria

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-012-9524-8

Adult Polyglucosan Body Disease (APBD): Anaplerotic diet therapy (Triheptanoin) and demonstration of defective methylation pathways

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3654543

Cognitive deficits in a genetic mouse model of the most common biochemical cause of human mental retardation.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3654543

Characteristics of an uptake system for alpha-aminoisobutyric acid in Leishmania tropica promastigotes

27 November 2018

1 reference

12 December 2020

Characterization of carrier-mediated transport systems for small neutral amino acids in human fibroblast lysosomes

1 reference

12 December 2020

Some characteristics of threonine transport across the blood-brain barrier of the rat

1 reference

12 December 2020

Facilitated transport of L-phenylalanine across blood-nerve barrier of rat peripheral nerve

1 reference

12 December 2020

Characteristics of alpha-aminoisobutyric acid transport by lactating rat mammary gland

1 reference

12 December 2020

Nutritional value of essential amino acids in the treatment of adults with phenylketonuria

1 reference

12 December 2020

Effects of feeding individual amino acids upon the distribution of other amino acids between cells and extracellular fluid

1 reference

12 December 2020

10.1007/S10545-012-9524-8

Identifiers

DOI

1 reference

Dimensions Publication ID

3680772

1013817241

0 references

3680772

1 reference

1 reference

1 reference