Fyn and ZAP-70 are required for Vav phosphorylation in T cells stimulated by antigen-presenting cells (Q28610639)

Structure and function of vav

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.48.31932

Defective T-cell receptor signalling and positive selection of Vav-deficient CD4+ CD8+ thymocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.48.31932

Defective antigen receptor-mediated proliferation of B and T cells in the absence of Vav.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.48.31932

Defective signalling through the T- and B-cell antigen receptors in lymphoid cells lacking the vav proto-oncogene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.48.31932

A functional T-cell receptor signaling pathway is required for p95vav activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.48.31932

Phosphotyrosine-dependent activation of Rac-1 GDP/GTP exchange by the vav proto-oncogene product

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.48.31932

Lck regulates Vav activation of members of the Rho family of GTPases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.48.31932

Rho: a connection between membrane receptor signalling and the cytoskeleton.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.48.31932

Defects in actin-cap formation in Vav-deficient mice implicate an actin requirement for lymphocyte signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.48.31932

Vav is a regulator of cytoskeletal reorganization mediated by the T-cell receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.48.31932

Faciogenital dysplasia protein (FGD1) and Vav, two related proteins required for normal embryonic development, are upstream regulators of Rho GTPases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.48.31932

Tyrosine phosphorylation of vav proto-oncogene product containing SH2 domain and transcription factor motifs

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.48.31932

Signal transduction by CD28 costimulatory receptor on T cells. B7-1 and B7-2 regulation of tyrosine kinase adaptor molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.48.31932

CD28/B7 system of T cell costimulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.48.31932

The CD19-CD21 complex regulates signal transduction thresholds governing humoral immunity and autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.48.31932

Functional and physical interactions of Syk family kinases with the Vav proto-oncogene product

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.48.31932

Regulation of Vav-SLP-76 binding by ZAP-70 and its relevance to TCR zeta/CD3 induction of interleukin-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.48.31932

Interactions between the protein-tyrosine kinase ZAP-70, the proto-oncoprotein Vav, and tubulin in Jurkat T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.48.31932

Vav and SLP-76 interact and functionally cooperate in IL-2 gene activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.48.31932

p95vav associates with tyrosine-phosphorylated SLP-76 in antigen-stimulated T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.48.31932

Differential regulation of T cell antigen responsiveness by isoforms of the src-related tyrosine protein kinase p59fyn

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.48.31932

p56lck interacts via its src homology 2 domain with the ZAP-70 kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.48.31932

Identification of a monoclonal antibody specific for a murine T3 polypeptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.48.31932

Mutation of tyrosines 492/493 in the kinase domain of ZAP-70 affects multiple T-cell receptor signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.48.31932

HLA-DR beta chain residues that are predicted to be located in the floor of the peptide-binding groove contribute to antibody-binding epitopes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.48.31932

Ligation of either CD2 or CD28 rescues CD4+ T cells from HIV-gp120-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.48.31932

Syk and ZAP-70 mediate recruitment of p56lck/CD4 to the activated T cell receptor/CD3/zeta complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.48.31932

Induction of T cell adhesion by antigen stimulation and modulation by the coreceptor CD4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.48.31932

CD28 signal transduction pathways. A comparison of B7-1 and B7-2 regulation of the map kinases: ERK2 and Jun kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.48.31932

Genetic evidence for the involvement of the lck tyrosine kinase in signal transduction through the T cell antigen receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.48.31932

The SH3 domain-binding T cell tyrosyl phosphoprotein p120. Demonstration of its identity with the c-cbl protooncogene product and in vivo complexes with Fyn, Grb2, and phosphatidylinositol 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.48.31932

Association of tyrosine protein kinase Zap-70 with the protooncogene product p120c-cbl in T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.48.31932

SH2 domains recognize specific phosphopeptide sequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.48.31932

Dominant-negative zeta-associated protein 70 inhibits T cell antigen receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.48.31932

Phosphorylation of SLP-76 by the ZAP-70 protein-tyrosine kinase is required for T-cell receptor function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.48.31932

CD28 affects the earliest signaling events generated by TCR engagement.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.48.31932

The Vav binding site (Y315) in ZAP-70 is critical for antigen receptor-mediated signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.48.31932

Two distinct regions of the CD28 intracytoplasmic domain are involved in the tyrosine phosphorylation of Vav and GTPase activating protein-associated p62 protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.48.31932

p56Lck and p59Fyn regulate CD28 binding to phosphatidylinositol 3-kinase, growth factor receptor-bound protein GRB-2, and T cell-specific protein-tyrosine kinase ITK: implications for T-cell costimulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.48.31932

Src-induced activation of inducible T cell kinase (ITK) requires phosphatidylinositol 3-kinase activity and the Pleckstrin homology domain of inducible T cell kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.48.31932

Lck phosphorylates the activation loop tyrosine of the Itk kinase domain and activates Itk kinase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.48.31932

Functional LCK Is required for optimal CD28-mediated activation of the TEC family tyrosine kinase EMT/ITK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.48.31932

Knockouts of Src-family kinases: stiff bones, wimpy T cells, and bad memories.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.48.31932

alpha beta T cell development is abolished in mice lacking both Lck and Fyn protein tyrosine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.48.31932

Vav: function and regulation in hematopoietic cell signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.48.31932

Catalytic specificity of protein-tyrosine kinases is critical for selective signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.48.31932

Activation of Src family members is not required for the platelet-derived growth factor beta receptor to initiate mitogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.48.31932

Alzheimer's disease. Mouse model made.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.48.31932