Cul4A is required for hematopoietic cell viability and its deficiency leads to apoptosis (Q28593134)

31 January 2017

title

Cul4A is required for hematopoietic cell viability and its deficiency leads to apoptosis (English)

1 reference

31 January 2017

1 reference

GOA release 2020-03-11

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David L. Waning

1

1 reference

31 January 2017

Binghui Li

2

1 reference

31 January 2017

Nan Jia

3

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31 January 2017

Yahaira Naaldijk

4

1 reference

31 January 2017

W. Scott Goebel

5

1 reference

31 January 2017

Harm HogenEsch

6

1 reference

31 January 2017

Kristin T. Chun

7

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31 January 2017

language of work or name

English

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publication date

15 July 2008

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31 January 2017

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31 January 2017

volume

112

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31 January 2017

issue

2

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31 January 2017

page(s)

320–329

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Cul4A is required for hematopoietic stem-cell engraftment and self-renewal

31 January 2017

cites work

1 reference

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Strength in numbers: preventing rereplication via multiple mechanisms in eukaryotic cells

17 March 2017

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Cul4A targets p27 for degradation and regulates proliferation, cell cycle exit, and differentiation during erythropoiesis

17 March 2017

1 reference

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Involvement of CUL4 ubiquitin E3 ligases in regulating CDK inhibitors Dacapo/p27Kip1 and cyclin E degradation

17 March 2017

1 reference

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Function and regulation of cullin-RING ubiquitin ligases

17 March 2017

1 reference

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Human De-etiolated-1 regulates c-Jun by assembling a CUL4A ubiquitin ligase

17 March 2017

1 reference

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Enforced expression of CUL-4A interferes with granulocytic differentiation and exit from the cell cycle

17 March 2017

1 reference

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CUL-4A is critical for early embryonic development

17 March 2017

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TFDP1, CUL4A, and CDC16 identified as targets for amplification at 13q34 in hepatocellular carcinomas

17 March 2017

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Effects of radiation damage on intestinal morphology

17 March 2017

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Mechanisms underlying ubiquitination

17 March 2017

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cul-1 is required for cell cycle exit in C. elegans and identifies a novel gene family

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442743

Inducible gene targeting in mice

17 March 2017

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A simple technique for quantitation of low levels of DNA damage in individual cells

7 April 2017

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DCAFs, the missing link of the CUL4-DDB1 ubiquitin ligase

7 April 2017

1 reference

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Cdt1 degradation to prevent DNA re-replication: conserved and non-conserved pathways

29 September 2017

1 reference

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DDB1 is essential for genomic stability in developing epidermis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442743

Stealing the spotlight: CUL4-DDB1 ubiquitin ligase docks WD40-repeat proteins to destroy

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442743

The Caenorhabditis elegans replication licensing factor CDT-1 is targeted for degradation by the CUL-4/DDB-1 complex

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442743

Beta common receptor inactivation attenuates myeloproliferative disease in Nf1 mutant mice

29 September 2017

1 reference

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Cdt1 revisited: complex and tight regulation during the cell cycle and consequences of deregulation in mammalian cells.

29 September 2017

1 reference

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Ubiquitylation in normal and malignant hematopoiesis: novel therapeutic targets

29 September 2017

1 reference

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L2DTL/CDT2 and PCNA interact with p53 and regulate p53 polyubiquitination and protein stability through MDM2 and CUL4A/DDB1 complexes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442743

Proteasome inhibitor bortezomib for the treatment of multiple myeloma.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442743

Monocyte accumulation in mouse atherogenesis is progressive and proportional to extent of disease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442743

Cul4A and DDB1 associate with Skp2 to target p27Kip1 for proteolysis involving the COP9 signalosome

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442743

Cullin 4A-mediated proteolysis of DDB2 protein at DNA damage sites regulates in vivo lesion recognition by XPC.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442743

Expression of endogenous oncogenic V600EB-raf induces proliferation and developmental defects in mice and transformation of primary fibroblasts

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442743

DDB2, the xeroderma pigmentosum group E gene product, is directly ubiquitylated by Cullin 4A-based ubiquitin ligase complex

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442743

Cul4A physically associates with MDM2 and participates in the proteolysis of p53.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442743

Elimination of background recombination: somatic induction of Cre by combined transcriptional regulation and hormone binding affinity.

29 September 2017

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A field guide to ubiquitylation

29 September 2017

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Oncogenic aberrations of cullin-dependent ubiquitin ligases

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442743

CUL-4A stimulates ubiquitylation and degradation of the HOXA9 homeodomain protein

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442743

A phase 2 study of bortezomib in relapsed, refractory myeloma

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442743

The xeroderma pigmentosum group E gene product DDB2 is a specific target of cullin 4A in mammalian cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442743

Cre-mediated germline mosaicism: a method allowing rapid generation of several alleles of a target gene.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442743

Radiation injury in surgical pathology. Part II. Alimentary tract.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442743

The origin and kinetics of mononuclear phagocytes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442743

C. elegans CUL-4 prevents rereplication by promoting the nuclear export of CDC-6 via a CKI-1-dependent pathway

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442743

Recognition and phagocytosis of cells undergoing apoptosis

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442743

Influence of polyinosinic: polycytidylic acid on the circulating white blood cells in mice

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442743

Circulating T and B lymphocytes of the mouse. II. Lifespan.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442743

Deletion of DDB1 in mouse brain and lens leads to p53-dependent elimination of proliferating cells.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442743

Tracking of leukocyte recruitment into tissues of mice by in situ labeling of blood cells with the fluorescent dye CFDA SE.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442743

Rac1-deficient macrophages exhibit defects in cell spreading and membrane ruffling but not migration

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442743

CUL-4 ubiquitin ligase maintains genome stability by restraining DNA-replication licensing

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442743

The human homologue for the Caenorhabditis elegans cul-4 gene is amplified and overexpressed in primary breast cancers.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442743

p27Kip1 overexpression causes apoptotic death of mammalian cells

27 November 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/18339895

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Interferon induces peripheral lymphadenopathy in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/18339895

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1182/BLOOD-2007-11-126300

1 reference

31 January 2017

0 references

1 reference