CARD6 is a modulator of NF-kappa B activation by Nod1- and Cardiak-mediated pathways (Q28592172)

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31 January 2017

Hideki Hayashi

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31 January 2017

Frederick Pio

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31 January 2017

John C. Reed

Journal of Biological Chemistry

5

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31 January 2017

language of work or name

English

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publication date

22 August 2003

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31 January 2017

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31 January 2017

278

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31 January 2017

31941–31949

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31 January 2017

34

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31 January 2017

PAAD - a new protein domain associated with apoptosis, cancer and autoimmune diseases.

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The CARD domain: a new apoptotic signalling motif

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Apoptotic molecular machinery: vastly increased complexity in vertebrates revealed by genome comparisons

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CARD games in apoptosis and immunity

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Caspase activation: the induced-proximity model

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Mechanisms of apoptosis

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The I kappa B kinase (IKK) and NF-kappa B: key elements of proinflammatory signalling

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NF-kappaB signaling pathways in mammalian and insect innate immunity

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The PAAD/PYRIN-family protein ASC is a dual regulator of a conserved step in nuclear factor kappaB activation pathways

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1 reference

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A novel PAAD-containing protein that modulates NF-kappa B induction by cytokines tumor necrosis factor-alpha and interleukin-1beta

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1 reference

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PYPAF1, a PYRIN-containing Apaf1-like protein that assembles with ASC and regulates activation of NF-kappa B

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1 reference

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PYPAF7, a novel PYRIN-containing Apaf1-like protein that regulates activation of NF-kappa B and caspase-1-dependent cytokine processing

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1 reference

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Functional screening of five PYPAF family members identifies PYPAF5 as a novel regulator of NF-kappaB and caspase-1.

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1 reference

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The PYRIN-CARD protein ASC is an activating adaptor for caspase-1

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Intracellular vs extracellular recognition of pathogens--common concepts in mammals and flies

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The NACHT family - a new group of predicted NTPases implicated in apoptosis and MHC transcription activation

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Toll-like receptors and innate immunity

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An induced proximity model for NF-kappa B activation in the Nod1/RICK and RIP signaling pathways

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Human Nod1 confers responsiveness to bacterial lipopolysaccharides

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1 reference

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CARD4/Nod1 mediates NF-kappaB and JNK activation by invasive Shigella flexneri.

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1 reference

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Nod1, a CARD protein, enhances pro-interleukin-1beta processing through the interaction with pro-caspase-1

21 January 2018

1 reference

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RIP2 is a novel NF-kappaB-activating and cell death-inducing kinase

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1 reference

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RICK, a novel protein kinase containing a caspase recruitment domain, interacts with CLARP and regulates CD95-mediated apoptosis

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1 reference

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Involvement of receptor-interacting protein 2 in innate and adaptive immune responses

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1 reference

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RICK/Rip2/CARDIAK mediates signalling for receptors of the innate and adaptive immune systems

21 January 2018

1 reference

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Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300009200

Gapped BLAST and PSI-BLAST: a new generation of protein database search programs

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1 reference

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Saturated BLAST: an automated multiple intermediate sequence search used to detect distant homology.

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Prediction of complete gene structures in human genomic DNA

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Comparative protein modelling by satisfaction of spatial restraints

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TUCAN, an antiapoptotic caspase-associated recruitment domain family protein overexpressed in cancer.

21 January 2018

1 reference

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A novel enhancer of the Apaf1 apoptosome involved in cytochrome c-dependent caspase activation and apoptosis

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1 reference

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CLAN, a novel human CED-4-like gene

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Cop, a caspase recruitment domain-containing protein and inhibitor of caspase-1 activation processing

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X-linked IAP is a direct inhibitor of cell-death proteases

21 January 2018

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Bcl10 is a positive regulator of antigen receptor-induced activation of NF-kappaB and neural tube closure

21 January 2018

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Altered cytokine export and apoptosis in mice deficient in interleukin-1 beta converting enzyme

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Regulation of IL-1beta generation by Pseudo-ICE and ICEBERG, two dominant negative caspase recruitment domain proteins

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ICEBERG: a novel inhibitor of interleukin-1beta generation

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Mitochondria and apoptosis

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Reduced apoptosis and cytochrome c-mediated caspase activation in mice lacking caspase 9

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Apaf1 is required for mitochondrial pathways of apoptosis and brain development

21 January 2018

1 reference

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Nod2, a Nod1/Apaf-1 family member that is restricted to monocytes and activates NF-kappaB

21 January 2018

1 reference

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TNF-R1 signaling: a beautiful pathway

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Bcl10 and MALT1, independent targets of chromosomal translocation in malt lymphoma, cooperate in a novel NF-kappa B signaling pathway

21 January 2018

1 reference

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Cutting edge: CATERPILLER: a large family of mammalian genes containing CARD, pyrin, nucleotide-binding, and leucine-rich repeat domains

21 January 2018

1 reference

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Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease

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A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease

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CARD15 mutations in Blau syndrome

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1 reference

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Human CARD4 protein is a novel CED-4/Apaf-1 cell death family member that activates NF-kappaB

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1 reference

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Nod1, an Apaf-1-like activator of caspase-9 and nuclear factor-kappaB

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CARDINAL, a novel caspase recruitment domain protein, is an inhibitor of multiple NF-kappa B activation pathways

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CARD-8 protein, a new CARD family member that regulates caspase-1 activation and apoptosis

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