Tissue transglutaminase contributes to disease progression in the R6/2 Huntington's disease mouse model via aggregate-independent mechanisms (Q28592026)

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English	Tissue transglutaminase contributes to disease progression in the R6/2 Huntington's disease mouse model via aggregate-independent mechanisms	scientific journal article

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scholarly article

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31 January 2017

Tissue transglutaminase contributes to disease progression in the R6/2 Huntington's disease mouse model via aggregate-independent mechanisms (English)

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31 January 2017

Huntington's disease

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author name string

Craig D. C. Bailey

1

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31 January 2017

Gail V. W. Johnson

2

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31 January 2017

language of work or name

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publication date

1 January 2005

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31 January 2017

Journal of Neurochemistry

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31 January 2017

92

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31 January 2017

83–92

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31 January 2017

1

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31 January 2017

Huntingtin aggregation and toxicity in Huntington's disease

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https://api.crossref.org/works/10.1111/J.1471-4159.2004.02839.X

21 April 2017

Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation

1 reference

https://api.crossref.org/works/10.1111/J.1471-4159.2004.02839.X

21 April 2017

Targeted inactivation of Gh/tissue transglutaminase II

1 reference

https://api.crossref.org/works/10.1111/J.1471-4159.2004.02839.X

21 April 2017

A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2004.02839.X

21 April 2017

A cell-based assay for aggregation inhibitors as therapeutics of polyglutamine-repeat disease and validation in Drosophila

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2004.02839.X

21 January 2018

Validity of mouse models for the study of tissue transglutaminase in neurodegenerative diseases.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2004.02839.X

21 January 2018

Differential hydrophobicity drives self-assembly in Huntington's disease

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2004.02839.X

21 January 2018

Tissue transglutaminase selectively modifies proteins associated with truncated mutant huntingtin in intact cells

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2004.02839.X

21 January 2018

Tissue transglutaminase does not contribute to the formation of mutant huntingtin aggregates

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2004.02839.X

21 January 2018

Standardization and statistical approaches to therapeutic trials in the R6/2 mouse

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2004.02839.X

21 January 2018

N(epsilon)-(gamma-L-glutamyl)-L-lysine (GGEL) is increased in cerebrospinal fluid of patients with Huntington's disease

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2004.02839.X

21 January 2018

Transglutaminase action imitates Huntington's disease: selective polymerization of Huntingtin containing expanded polyglutamine.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2004.02839.X

21 January 2018

Transglutaminase aggregates huntingtin into nonamyloidogenic polymers, and its enzymatic activity increases in Huntington's disease brain nuclei

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2004.02839.X

21 January 2018

Prolonged survival and decreased abnormal movements in transgenic model of Huntington disease, with administration of the transglutaminase inhibitor cystamine

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2004.02839.X

21 January 2018

Effect of tissue transglutaminase on the solubility of proteins containing expanded polyglutamine repeats.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2004.02839.X

21 January 2018

Tissue transglutaminase: a possible role in neurodegenerative diseases

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2004.02839.X

21 January 2018

Cystamine inhibits caspase activity. Implications for the treatment of polyglutamine disorders

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2004.02839.X

21 January 2018

Transglutaminases: crosslinking enzymes with pleiotropic functions

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2004.02839.X

21 January 2018

Transglutaminase and neuronal differentiation

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2004.02839.X

21 January 2018

Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2004.02839.X

21 January 2018

'Tissue' transglutaminase ablation reduces neuronal death and prolongs survival in a mouse model of Huntington's disease

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2004.02839.X

21 January 2018

Tissue transglutaminase and apoptosis: sense and antisense transfection studies with human neuroblastoma cells

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2004.02839.X

21 January 2018

Inhibition of "tissue" transglutaminase increases cell survival by preventing apoptosis

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2004.02839.X

21 January 2018

A Rapid Cellular FRET Assay of Polyglutamine Aggregation Identifies a Novel Inhibitor

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2004.02839.X

21 January 2018

Pivotal role of oligomerization in expanded polyglutamine neurodegenerative disorders.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2004.02839.X

21 January 2018

Huntingtin acts in the nucleus to induce apoptosis but death does not correlate with the formation of intranuclear inclusions.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2004.02839.X

21 January 2018

Trehalose alleviates polyglutamine-mediated pathology in a mouse model of Huntington disease

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2004.02839.X

21 January 2018

Tissue transglutaminase differentially modulates apoptosis in a stimuli-dependent manner

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2004.02839.X

21 January 2018

Tissue transglutaminase is essential for neurite outgrowth in human neuroblastoma SH-SY5Y cells

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2004.02839.X

21 January 2018

Aggregated polyglutamine peptides delivered to nuclei are toxic to mammalian cells

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2004.02839.X

21 January 2018

Huntingtin inclusions do not deplete polyglutamine-containing transcription factors in HD mice

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2004.02839.X

21 January 2018

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