PDK1 coordinates survival pathways and beta-adrenergic response in the heart (Q28585494)

GOA release 2020-03-11

15

Issei Komuro

1 reference

31 January 2017

11

Jeffery D. Molkentin

1 reference

31 January 2017

6

Noritaka Yasuda

1 reference

31 January 2017

3

Masaji Tamagawa

1 reference

31 January 2017

2

Hiroshi Akazawa

1 reference

31 January 2017

Kaoru Ito

1

1 reference

31 January 2017

Kensuke Furukawa

4

1 reference

31 January 2017

Wataru Ogawa

5

1 reference

31 January 2017

Yoko Kudo

7

1 reference

31 January 2017

Chien-hui Liao

8

1 reference

31 January 2017

Rie Yamamoto

9

1 reference

31 January 2017

Toshiaki Sato

10

1 reference

31 January 2017

Masato Kasuga

12

1 reference

31 January 2017

Tetsuo Noda

13

1 reference

31 January 2017

Haruaki Nakaya

Proceedings of the National Academy of Sciences of the United States of America

14

1 reference

31 January 2017

language of work or name

English

0 references

publication date

26 May 2009

1 reference

31 January 2017

1 reference

31 January 2017

106

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31 January 2017

8689–8694

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31 January 2017

21

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31 January 2017

AKT/PKB signaling: navigating downstream

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688981

Transduction of receptor signals by beta-arrestins

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688981

Serum and glucocorticoid-responsive kinase-1 regulates cardiomyocyte survival and hypertrophic response

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688981

Essential role of PDK1 in regulating cell size and development in mice

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688981

Protein kinase SGK mediates survival signals by phosphorylating the forkhead transcription factor FKHRL1 (FOXO3a)

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688981

G protein-coupled receptor kinase 2 ablation in cardiac myocytes before or after myocardial infarction prevents heart failure

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688981

Tackling heart failure in the twenty-first century

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688981

Beta-arrestin-mediated beta1-adrenergic receptor transactivation of the EGFR confers cardioprotection.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688981

3'Phosphoinositide-dependent kinase-1 is essential for ischemic preconditioning of the myocardium.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688981

Protein kinase activity of phosphoinositide 3-kinase regulates beta-adrenergic receptor endocytosis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688981

Death begets failure in the heart

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688981

Inhibition of receptor-localized PI3K preserves cardiac beta-adrenergic receptor function and ameliorates pressure overload heart failure

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688981

Deficiency of PDK1 in cardiac muscle results in heart failure and increased sensitivity to hypoxia

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688981

Linkage of beta1-adrenergic stimulation to apoptotic heart cell death through protein kinase A-independent activation of Ca2+/calmodulin kinase II.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688981

Seven-transmembrane-spanning receptors and heart function

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688981

Cardiac beta ARK1 inhibition prolongs survival and augments beta blocker therapy in a mouse model of severe heart failure

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688981

In vivo ventricular gene delivery of a beta-adrenergic receptor kinase inhibitor to the failing heart reverses cardiac dysfunction

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688981

Cellular signaling: pivoting around PDK-1.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688981

Deficiency of PDK1 in liver results in glucose intolerance, impairment of insulin-regulated gene expression and liver failure

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688981

Requirement for 3-phosphoinositide-kependent dinase-1 (PDK-1) in insulin-induced glucose uptake in immortalized brown adipocytes

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688981

The "Modern" View of Heart Failure: How Did We Get Here?

3 June 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0900064106

Role of hepatic STAT3 in brain-insulin action on hepatic glucose production.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0900064106

Temporally regulated and tissue-specific gene manipulations in the adult and embryonic heart using a tamoxifen-inducible Cre protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0900064106

The role of 3-phosphoinositide-dependent protein kinase 1 in activating AGC kinases defined in embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0900064106

Transgenic expression of Bcl-2 modulates energy metabolism, prevents cytosolic acidification during ischemia, and reduces ischemia/reperfusion injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0900064106

Restoration of beta-adrenergic receptor signaling and contractile function in heart failure by disruption of the betaARK1/phosphoinositide 3-kinase complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0900064106

Restoration of glucokinase expression in the liver normalizes postprandial glucose disposal in mice with hepatic deficiency of PDK1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0900064106

PDK1 deficiency in POMC-expressing cells reveals FOXO1-dependent and -independent pathways in control of energy homeostasis and stress response

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0900064106

PI3Kγ Modulates the Cardiac Response to Chronic Pressure Overload by Distinct Kinase-Dependent and -Independent Effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0900064106

Functional roles of cardiac and vascular ATP-sensitive potassium channels clarified by Kir6.2-knockout mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0900064106

Navigating the signalling network in mouse cardiac myocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0900064106

Phosphoinositide 3-kinase is required for insulin-induced but not for growth hormone- or hyperosmolarity-induced glucose uptake in 3T3-L1 adipocytes

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688981

Diphtheria toxin-induced autophagic cardiomyocyte death plays a pathogenic role in mouse model of heart failure

27 November 2018

1 reference

12 December 2020

A muscle-specific insulin receptor knockout exhibits features of the metabolic syndrome of NIDDM without altering glucose tolerance

1 reference

12 December 2020

Responses of cardiac protein kinase C isoforms to distinct pathological stimuli are differentially regulated

1 reference

12 December 2020

Ablation of PDK1 in pancreatic beta cells induces diabetes as a result of loss of beta cell mass

1 reference

12 December 2020