Blockade of IRS1 in isolated rat pancreatic islets improves glucose-induced insulin secretion (Q28577340)

31 January 2017

title

Blockade of IRS1 in isolated rat pancreatic islets improves glucose-induced insulin secretion (English)

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31 January 2017

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4

Silvana Bordin

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31 January 2017

9

Lício A. Velloso

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Maria Esméria Corezola do Amaral

31 January 2017

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ORCID Public Data File 2021

author name string

Eliana P. Araujo

1

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31 January 2017

Maria E. C. Amaral

2

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31 January 2017

Cláudio T. Souza

3

1 reference

31 January 2017

Fabiano Ferreira

5

1 reference

31 January 2017

Mario J. A. Saad

6

1 reference

31 January 2017

Antonio C. Boschero

7

1 reference

31 January 2017

Everardo C. Magalhães

8

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31 January 2017

language of work or name

English

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publication date

20 November 2002

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31 January 2017

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31 January 2017

volume

531

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31 January 2017

issue

3

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31 January 2017

page(s)

437–442

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Evidence for presence of insulin receptors in rat islets of Langerhans

31 January 2017

cites work

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21 January 2018

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21 January 2018

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Disruption of IRS-2 causes type 2 diabetes in mice

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Roles of insulin receptor substrate-1, phosphatidylinositol 3-kinase, and release of intracellular Ca2+ stores in insulin-stimulated insulin secretion in beta -cells.

21 January 2018

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Insulin activates ATP-sensitive K(+) channels in pancreatic beta-cells through a phosphatidylinositol 3-kinase-dependent pathway

21 January 2018

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Insulin receptor substrate 1-induced inhibition of endoplasmic reticulum Ca2+ uptake in beta-cells. Autocrine regulation of intracellular ca2+ homeostasis and insulin secretion

21 January 2018

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Activation of IRS-2-mediated signal transduction by IGF-1, but not TGF-alpha or EGF, augments pancreatic beta-cell proliferation

21 January 2018

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Disruption of insulin receptor substrate 2 causes type 2 diabetes because of liver insulin resistance and lack of compensatory beta-cell hyperplasia.

21 January 2018

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Insulin receptor activation inhibits insulin secretion from human islets of Langerhans

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GAD autoantibodies in IDDM, stiff-man syndrome, and autoimmune polyendocrine syndrome type I recognize different epitopes

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Effect of the insulin mimetic L-783,281 on intracellular Ca2+ and insulin secretion from pancreatic beta-cells

21 January 2018

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Phosphatidylinositol 3-kinase signaling to Akt mediates survival in isolated canine islets of Langerhans

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Reduced expression of the murine p85alpha subunit of phosphoinositide 3-kinase improves insulin signaling and ameliorates diabetes

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Insulin, Glucagon, and Somatostatin Secretion in the Regulation of Metabolism

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Somatostatin Release from Isolated Perfused Rat Pancreas: Possible Role of Endogenous Somatostatin on Insulin Release

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Altered function of insulin receptor substrate-1-deficient mouse islets and cultured beta-cell lines

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Glucose- and insulin-induced phosphorylation of the insulin receptor and its primary substrates IRS-1 and IRS-2 in rat pancreatic islets

21 January 2018

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7 January 2021

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7 January 2021

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beta-cell-specific deletion of the Igf1 receptor leads to hyperinsulinemia and glucose intolerance but does not alter beta-cell mass

7 January 2021

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Chronic effects of insulin and glucagon upon islet function

7 January 2021

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Effect of captopril, losartan, and bradykinin on early steps of insulin action

7 January 2021

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7 January 2021

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inferred from DOI database lookup

7 January 2021

based on heuristic

Integrative mitogenic role of protein kinase B/Akt in beta-cells.

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Pancreatic hormone receptors on islet cells

7 January 2021

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10.1016/S0014-5793(02)03580-9

7 January 2021

Identifiers

DOI

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