Epidermal growth factor-induced phosphatidylinositol 3-kinase activation and DNA synthesis. Identification of Grb2-associated binder 2 as the major mediator in rat hepatocytes (Q28571849)

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English	Epidermal growth factor-induced phosphatidylinositol 3-kinase activation and DNA synthesis. Identification of Grb2-associated binder 2 as the major mediator in rat hepatocytes	scientific journal article

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scholarly article

1 reference

31 January 2017

Epidermal growth factor-induced phosphatidylinositol 3-kinase activation and DNA synthesis. Identification of Grb2-associated binder 2 as the major mediator in rat hepatocytes (English)

1 reference

31 January 2017

author name string

M. Kong

1

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31 January 2017

C. Mounier

2

1 reference

31 January 2017

J. Wu

3

1 reference

31 January 2017

B. I. Posner

4

1 reference

31 January 2017

language of work or name

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publication date

17 November 2000

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31 January 2017

Journal of Biological Chemistry

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31 January 2017

275

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31 January 2017

46

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31 January 2017

36035–36042

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31 January 2017

PDGF-dependent tyrosine phosphorylation stimulates production of novel polyphosphoinositides in intact cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005621200

21 January 2018

Type I phosphatidylinositol kinase makes a novel inositol phospholipid, phosphatidylinositol-3-phosphate

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005621200

21 January 2018

cDNA cloning of a Novel 85 kd protein that has SH2 domains and regulates binding of PI3-kinase to the PDGF β-receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005621200

21 January 2018

Structure of an SH2 domain of the p85 alpha subunit of phosphatidylinositol-3-OH kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005621200

21 January 2018

Phosphatidylinositol 3-kinase activation is mediated by high-affinity interactions between distinct domains within the p110 and p85 subunits

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005621200

21 January 2018

Microinjection of the SH2 domain of the 85-kilodalton subunit of phosphatidylinositol 3-kinase inhibits insulin-induced DNA synthesis and c-fos expression

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005621200

21 January 2018

Phosphatidylinositol 3-kinase activation is required for insulin stimulation of pp70 S6 kinase, DNA synthesis, and glucose transporter translocation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005621200

21 January 2018

Stimulation of mitogenesis by a cell-permeable PI 3-kinase binding peptide

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005621200

21 January 2018

The phosphatidylinositol 3-kinase alpha is required for DNA synthesis induced by some, but not all, growth factors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005621200

21 January 2018

Identification of a 190-kDa protein as a novel substrate for the insulin receptor kinase functionally similar to insulin receptor substrate-1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005621200

21 January 2018

Activated type I phosphatidylinositol kinase is associated with the epidermal growth factor (EGF) receptor following EGF stimulation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005621200

21 January 2018

ErbB3 is involved in activation of phosphatidylinositol 3-kinase by epidermal growth factor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005621200

21 January 2018

p120cbl is a cytosolic adapter protein that associates with phosphoinositide 3-kinase in response to epidermal growth factor in PC12 and other cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005621200

21 January 2018

A Grb2-associated docking protein in EGF- and insulin-receptor signalling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005621200

21 January 2018

Engagement of Gab1 and Gab2 in erythropoietin signaling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005621200

21 January 2018

Gab2, a new pleckstrin homology domain-containing adapter protein, acts to uncouple signaling from ERK kinase to Elk-1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005621200

21 January 2018

Cloning of p97/Gab2, the major SHP2-binding protein in hematopoietic cells, reveals a novel pathway for cytokine-induced gene activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005621200

21 January 2018

A simplified system for generating recombinant adenoviruses

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005621200

21 January 2018

Specific activation of p85-p110 phosphatidylinositol 3'-kinase stimulates DNA synthesis by ras- and p70 S6 kinase-dependent pathways

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005621200

21 January 2018

A region of the 85-kilodalton (kDa) subunit of phosphatidylinositol 3-kinase binds the 110-kDa catalytic subunit in vivo

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005621200

21 January 2018

Insulin regulates heregulin binding and ErbB3 expression in rat hepatocytes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005621200

21 January 2018

Association of the Shc and Grb2/Sem5 SH2-containing proteins is implicated in activation of the Ras pathway by tyrosine kinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005621200

21 January 2018

Epidermal growth factor induces coupling of protein-tyrosine phosphatase 1D to GRB2 via the COOH-terminal SH3 domain of GRB2

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005621200

21 January 2018

Direct association of Grb2 with the p85 subunit of phosphatidylinositol 3-kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005621200

21 January 2018

Wortmannin inactivates phosphoinositide 3-kinase by covalent modification of Lys-802, a residue involved in the phosphate transfer reaction

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005621200

21 January 2018

A synthetic inhibitor of the mitogen-activated protein kinase cascade

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005621200

21 January 2018

Cloning and characterization of a wortmannin-sensitive human phosphatidylinositol 4-kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005621200

21 January 2018

Distinct phosphotyrosines on a growth factor receptor bind to specific molecules that mediate different signaling pathways

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005621200

21 January 2018

Association between phosphatidylinositol-3 kinase, Cbl and other tyrosine phosphorylated proteins in colony-stimulating factor-1-stimulated macrophages

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005621200

21 January 2018

Alternatively spliced juxtamembrane domain of a tyrosine kinase receptor is a multifunctional regulatory site. Deletion alters cellular tyrosine phosphorylation pattern and facilitates binding of phosphatidylinositol-3-OH kinase to the hepatocyte gr

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005621200

21 January 2018

An epidermal growth factor receptor/Gab1 signaling pathway is required for activation of phosphoinositide 3-kinase by lysophosphatidic acid.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005621200

21 January 2018

A new tyrosine-phosphorylated 97-kDa adaptor protein mediates interleukin-2-induced association of SHP-2 with p85-phosphatidylinositol 3-kinase in human T lymphocytes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005621200

21 January 2018

The Gab1 protein is a docking site for multiple proteins involved in signaling by the B cell antigen receptor.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005621200

21 January 2018

Identifiers

10.1074/JBC.M005621200

1 reference

31 January 2017

1 reference

31 January 2017

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