BMP-2-induced Runx2 expression is mediated by Dlx5, and TGF-beta 1 opposes the BMP-2-induced osteoblast differentiation by suppression of Dlx5 expression (Q28570736)

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English	BMP-2-induced Runx2 expression is mediated by Dlx5, and TGF-beta 1 opposes the BMP-2-induced osteoblast differentiation by suppression of Dlx5 expression	scientific journal article

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scholarly article

1 reference

31 January 2017

BMP-2-induced Runx2 expression is mediated by Dlx5, and TGF-beta 1 opposes the BMP-2-induced osteoblast differentiation by suppression of Dlx5 expression (English)

1 reference

31 January 2017

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author name string

Mi-Hye Lee

1

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31 January 2017

Youn-Jeong Kim

2

1 reference

31 January 2017

Hyun-Jung Kim

3

1 reference

31 January 2017

Hyun-Dong Park

4

1 reference

31 January 2017

Ae-Ree Kang

5

1 reference

31 January 2017

Hee-Moon Kyung

6

1 reference

31 January 2017

Jae-Hyun Sung

7

1 reference

31 January 2017

John M. Wozney

8

1 reference

31 January 2017

Hyun-Jung Kim

9

1 reference

31 January 2017

Hyun-Mo Ryoo

10

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31 January 2017

language of work or name

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publication date

5 September 2003

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31 January 2017

Journal of Biological Chemistry

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31 January 2017

278

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31 January 2017

34387–34394

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31 January 2017

36

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31 January 2017

Bone: formation by autoinduction

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211386200

21 January 2018

Recombinant human bone morphogenetic protein-2 stimulates osteoblastic maturation and inhibits myogenic differentiation in vitro

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211386200

21 January 2018

Bone morphogenetic protein-2 converts the differentiation pathway of C2C12 myoblasts into the osteoblast lineage

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https://api.crossref.org/works/10.1074%2FJBC.M211386200

21 January 2018

TGF-beta signalling from cell membrane to nucleus through SMAD proteins

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https://api.crossref.org/works/10.1074%2FJBC.M211386200

21 January 2018

A kinase domain-truncated type I receptor blocks bone morphogenetic protein-2-induced signal transduction in C2C12 myoblasts

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211386200

21 January 2018

Constitutively active BMP type I receptors transduce BMP-2 signals without the ligand in C2C12 myoblasts.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211386200

21 January 2018

Smad1 and smad5 act downstream of intracellular signalings of BMP-2 that inhibits myogenic differentiation and induces osteoblast differentiation in C2C12 myoblasts

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211386200

21 January 2018

Smad5 and DPC4 are key molecules in mediating BMP-2-induced osteoblastic differentiation of the pluripotent mesenchymal precursor cell line C2C12.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211386200

21 January 2018

Runx2 is a common target of transforming growth factor beta1 and bone morphogenetic protein 2, and cooperation between Runx2 and Smad5 induces osteoblast-specific gene expression in the pluripotent mesenchymal precursor cell line C2C12.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211386200

21 January 2018

Osf2/Cbfa1: a transcriptional activator of osteoblast differentiation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211386200

21 January 2018

Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211386200

21 January 2018

A RUNX2/PEBP2alpha A/CBFA1 mutation displaying impaired transactivation and Smad interaction in cleidocranial dysplasia

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211386200

21 January 2018

A BMP-inducible gene, dlx5, regulates osteoblast differentiation and mesoderm induction

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211386200

21 January 2018

Regulation of the activity of the transcription factor Runx2 by two homeobox proteins, Msx2 and Dlx5

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211386200

21 January 2018

Overexpression of Dlx5 in chicken calvarial cells accelerates osteoblastic differentiation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211386200

21 January 2018

Cloning and characterization of two members of the vertebrate Dlx gene family

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211386200

21 January 2018

rDlx, a novel distal-less-like homeoprotein is expressed in developing cartilages and discrete neuronal tissues

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211386200

21 January 2018

The Dlx5 and Dlx6 homeobox genes are essential for craniofacial, axial, and appendicular skeletal development

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211386200

21 January 2018

Ectopic induction of tendon and ligament in rats by growth and differentiation factors 5, 6, and 7, members of the TGF-beta gene family

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211386200

21 January 2018

Hedgehog proteins stimulate chondrogenic cell differentiation and cartilage formation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211386200

21 January 2018

Cellular hypertrophy and calcification of embryonal carcinoma-derived chondrogenic cell line ATDC5 in vitro

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211386200

21 January 2018

Syntaxin 4, VAMP2, and/or VAMP3/cellubrevin are functional target membrane and vesicle SNAP receptors for insulin-stimulated GLUT4 translocation in adipocytes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211386200

21 January 2018

Roles of bone morphogenetic protein type I receptors and Smad proteins in osteoblast and chondroblast differentiation.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211386200

21 January 2018

Both the Smad and p38 MAPK pathways play a crucial role in Runx2 expression following induction by transforming growth factor-beta and bone morphogenetic protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211386200

21 January 2018

Opposite effects of bone morphogenetic protein-2 and transforming growth factor-beta1 on osteoblast differentiation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211386200

21 January 2018

A dominant negative to activation protein-1 (AP1) that abolishes DNA binding and inhibits oncogenesis.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211386200

21 January 2018

The protein kinase C pathway plays a central role in the fibroblast growth factor-stimulated expression and transactivation activity of Runx2

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211386200

21 January 2018

TGF-beta-induced repression of CBFA1 by Smad3 decreases cbfa1 and osteocalcin expression and inhibits osteoblast differentiation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211386200

21 January 2018

Enhanced jun gene expression is an early genomic response to transforming growth factor beta stimulation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211386200

21 January 2018

Early gene responses associated with transforming growth factor-beta 1 growth inhibition and autoinduction in MCF-7 breast adenocarcinoma cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211386200

21 January 2018

Smad3-Smad4 and AP-1 complexes synergize in transcriptional activation of the c-Jun promoter by transforming growth factor beta

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211386200

21 January 2018

Role of activator protein 1 transcriptional activity in the regulation of gene expression by transforming growth factor beta1 and bone morphogenetic protein 2 in ROS 17/2.8 osteoblast-like cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211386200

21 January 2018

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