Comparison of substrate specificity of the ubiquitin ligases Nedd4 and Nedd4-2 using proteome arrays (Q28566104)

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1 reference

31 January 2017

Philipp Alberts

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31 January 2017

Eva M. Amsen

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31 January 2017

Xuejian Xiong

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31 January 2017

James Wasmuth

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31 January 2017

Zachary Saadon

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31 January 2017

Chris Fladd

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31 January 2017

John Parkinson

Molecular Systems Biology

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31 January 2017

1 January 2009

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31 January 2017

describes a project that uses

Cytoscape

1 reference

Europe PubMed Central

9 June 2022

https://europepmc.org/search?query=(METHODS:'Cytoscape')

based on heuristic

inferred from PubMed Central ID database lookup

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Nedd4 and Nedd4-2: closely related ubiquitin-protein ligases with distinct physiological functions

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The inositol phosphatase MTMR4 is a novel target of the ubiquitin ligase Nedd4

19 March 2017

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Nedd4 augments the adaptive immune response by promoting ubiquitin-mediated degradation of Cbl-b in activated T cells

19 March 2017

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Nedd4 controls animal growth by regulating IGF-1 signaling

19 March 2017

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The ubiquitin-protein ligase Nedd4-2 differentially interacts with and regulates members of the Tweety family of chloride ion channels

19 March 2017

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The ubiquitin ligase Nedd4-1 is dispensable for the regulation of PTEN stability and localization

19 March 2017

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Salt-sensitive hypertension and cardiac hypertrophy in mice deficient in the ubiquitin ligase Nedd4-2

19 March 2017

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Regulation of Nedd4-2 self-ubiquitination and stability by a PY motif located within its HECT-domain

19 March 2017

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Ear1p and Ssh4p are new adaptors of the ubiquitin ligase Rsp5p for cargo ubiquitylation and sorting at multivesicular bodies

19 March 2017

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The BioGRID Interaction Database: 2008 update

19 March 2017

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Damage-induced ubiquitylation of human RNA polymerase II by the ubiquitin ligase Nedd4, but not Cockayne syndrome proteins or BRCA1

19 March 2017

1 reference

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EAAT4 phosphorylation at the SGK1 consensus site is required for transport modulation by the kinase

19 March 2017

1 reference

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Direct binding to Rsp5p regulates ubiquitination-independent vacuolar transport of Sna3p.

19 March 2017

1 reference

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Regulation of the voltage-gated K(+) channels KCNQ2/3 and KCNQ3/5 by ubiquitination. Novel role for Nedd4-2

19 March 2017

1 reference

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The KCNQ1 potassium channel is down-regulated by ubiquitylating enzymes of the Nedd4/Nedd4-like family

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824488

Direct binding to Rsp5 mediates ubiquitin-independent sorting of Sna3 via the multivesicular body pathway.

19 March 2017

1 reference

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Characterization of multiple multivesicular body sorting determinants within Sna3: a role for the ubiquitin ligase Rsp5.

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824488

Transport of LAPTM5 to lysosomes requires association with the ubiquitin ligase Nedd4, but not LAPTM5 ubiquitination

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824488

Ubiquitin ligase Smurf1 controls osteoblast activity and bone homeostasis by targeting MEKK2 for degradation

19 March 2017

1 reference

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Cardiac voltage-gated sodium channel Nav1.5 is regulated by Nedd4-2 mediated ubiquitination

19 March 2017

1 reference

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Cytoscape: a software environment for integrated models of biomolecular interaction networks

19 March 2017

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The Grb10/Nedd4 complex regulates ligand-induced ubiquitination and stability of the insulin-like growth factor I receptor

19 March 2017

1 reference

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Signal transduction by the TGF-beta superfamily

19 March 2017

1 reference

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The ubiquitin-proteasome proteolytic pathway: destruction for the sake of construction

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824488

Nedd4 regulates ubiquitination and stability of the guanine-nucleotide exchange factor CNrasGEF

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824488

Solution structure of a Nedd4 WW domain-ENaC peptide complex

19 March 2017

1 reference

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The Nedd4-like protein KIAA0439 is a potential regulator of the epithelial sodium channel

19 March 2017

1 reference

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A novel mouse Nedd4 protein suppresses the activity of the epithelial Na+ channel

19 March 2017

1 reference

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mGrb10 interacts with Nedd4

19 March 2017

1 reference

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Preservation of duplicate genes by complementary, degenerative mutations

19 March 2017

1 reference

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Characterization of the WW domain of human yes-associated protein and its polyproline-containing ligands

19 March 2017

1 reference

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The large subunit of RNA polymerase II is a substrate of the Rsp5 ubiquitin-protein ligase

19 March 2017

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Cell surface expression of the epithelial Na channel and a mutant causing Liddle syndrome: a quantitative approach

19 March 2017

1 reference

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WW domains of Nedd4 bind to the proline-rich PY motifs in the epithelial Na+ channel deleted in Liddle's syndrome

19 March 2017

1 reference

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Automatic clustering of orthologs and in-paralogs from pairwise species comparisons

19 March 2017

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Physiological functions of the HECT family of ubiquitin ligases

7 April 2017

1 reference

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7 April 2017

1 reference

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Targeting proteins for destruction by the ubiquitin system: implications for human pathobiology

7 April 2017

1 reference

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Targeting of Sna3p to the endosomal pathway depends on its interaction with Rsp5p and multivesicular body sorting on its ubiquitylation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824488

The PY motif of ENaC, mutated in Liddle syndrome, regulates channel internalization, sorting and mobilization from subapical pool

29 September 2017

1 reference

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Ubiquitination screen using protein microarrays for comprehensive identification of Rsp5 substrates in yeast

29 September 2017

1 reference

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Ubiquitylation of ion channels

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824488

Regulation of CLC-Ka/barttin by the ubiquitin ligase Nedd4-2 and the serum- and glucocorticoid-dependent kinases

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824488

Nedd4-2 functionally interacts with ClC-5: involvement in constitutive albumin endocytosis in proximal tubule cells

29 September 2017

1 reference

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Serum and glucocorticoid inducible kinases functionally regulate ClC-2 channels

29 September 2017

1 reference

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Regulation of neuronal voltage-gated sodium channels by the ubiquitin-protein ligases Nedd4 and Nedd4-2.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824488

Regulation of the glutamate transporter EAAT1 by the ubiquitin ligase Nedd4-2 and the serum and glucocorticoid-inducible kinase isoforms SGK1/3 and protein kinase B.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824488

Ligand-independent degradation of epidermal growth factor receptor involves receptor ubiquitylation and Hgs, an adaptor whose ubiquitin-interacting motif targets ubiquitylation by Nedd4.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824488

Distinct characteristics of two human Nedd4 proteins with respect to epithelial Na(+) channel regulation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824488

Characterizing Class I WW domains defines key specificity determinants and generates mutant domains with novel specificities

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824488

Defective regulation of the epithelial Na+ channel by Nedd4 in Liddle's syndrome.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824488

Modulation of the voltage-gated potassium channel Kv1.5 by the SGK1 protein kinase involves inhibition of channel ubiquitination.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824488

Communication between Distant Sites in RNA Polymerase II through Ubiquitylation Factors and the Polymerase CTD

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824488

Post-translational regulation of EAAT2 function by co-expressed ubiquitin ligase Nedd4-2 is impacted by SGK kinases.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824488

Structural determinants for high-affinity binding in a Nedd4 WW3* domain-Comm PY motif complex

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824488

Regulation of intestinal phosphate cotransporter NaPi IIb by ubiquitin ligase Nedd4-2 and by serum- and glucocorticoid-dependent kinase 1.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824488

Regulation of the voltage gated K+ channel Kv1.3 by the ubiquitin ligase Nedd4-2 and the serum and glucocorticoid inducible kinase SGK1.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824488

Regulation of the cardiac voltage-gated Na+ channel (H1) by the ubiquitin-protein ligase Nedd4.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824488

A mouse model for Liddle's syndrome

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19953087

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Regulation of the glutamate transporter EAAT1 by the ubiquitin ligase Nedd4-2 and the serum and glucocorticoid-inducible kinase isoforms SGK1/3 and protein kinase B

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FMSB.2009.85

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/MSB.2009.85

1 reference

1116372

1116372

1 reference

1 reference

1 reference