Angiotensin II-induced skeletal muscle insulin resistance mediated by NF-kappaB activation via NADPH oxidase (Q28564620)

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31 January 2017

Suzanne E. Clark

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Wenhan Li

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Carlos M. Ferrario

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Craig S. Stump

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E345–351

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Series introduction: the transcription factor NF-kappaB and human disease

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Role of the adipocyte, free fatty acids, and ectopic fat in pathogenesis of type 2 diabetes mellitus: peroxisomal proliferator-activated receptor agonists provide a rational therapeutic approach

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Abrogation of oxidative stress improves insulin sensitivity in the Ren-2 rat model of tissue angiotensin II overexpression

21 January 2018

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Local and systemic insulin resistance resulting from hepatic activation of IKK-beta and NF-kappaB

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Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes

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Reduction of the accumulation of advanced glycation end products by ACE inhibition in experimental diabetic nephropathy

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Selective angiotensin II receptor antagonism reduces insulin resistance in obese Zucker rats

21 January 2018

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Hydrogen peroxide activates IkappaB kinases through phosphorylation of serine residues in the activation loops

21 January 2018

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Differential expression of the GLUT1 and GLUT4 glucose transporters during differentiation of L6 muscle cells

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Specificity of a third kind: reactive oxygen and nitrogen intermediates in cell signaling

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Angiotensin II-induced insulin resistance is associated with enhanced insulin signaling

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Erythrophagocytosis by liver macrophages (Kupffer cells) promotes oxidative stress, inflammation, and fibrosis in a rabbit model of steatohepatitis: implications for the pathogenesis of human nonalcoholic steatohepatitis.

21 January 2018

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TNF-alpha and insulin resistance: summary and future prospects

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Angiotensin II-mediated hypertension in the rat increases vascular superoxide production via membrane NADH/NADPH oxidase activation. Contribution to alterations of vasomotor tone

21 January 2018

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Novel competitive inhibitor of NAD(P)H oxidase assembly attenuates vascular O(2)(-) and systolic blood pressure in mice.

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Angiotensin II induces insulin resistance independent of changes in interstitial insulin

21 January 2018

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Inflammation and insulin resistance

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Fatty acid-induced insulin resistance in L6 myotubes is prevented by inhibition of activation and nuclear localization of nuclear factor kappa B

21 January 2018

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Defective insulin signaling in skeletal muscle of the hypertensive TG(mREN2)27 rat.

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Hypertension, angiotensin II, and oxidative stress

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Protein kinase B kinases that mediate phosphatidylinositol 3,4,5-trisphosphate-dependent activation of protein kinase B

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NF-kappaB: a key role in inflammatory diseases

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Mechanisms of reactive oxygen species-dependent downregulation of insulin receptor substrate-1 by angiotensin II.

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Improved insulin action and glycemic control after long-term angiotensin-converting enzyme inhibition in subjects with arterial hypertension and type II diabetes.

21 January 2018

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Angiotensin II-induced NADPH oxidase activation impairs insulin signaling in skeletal muscle cells.

21 January 2018

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Effects of an angiotensin-converting-enzyme inhibitor, ramipril, on cardiovascular events in high-risk patients

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Glycated proteins stimulate reactive oxygen species production in cardiac myocytes: involvement of Nox2 (gp91phox)-containing NADPH oxidase

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