Activating transcription factor 6 is necessary and sufficient for alcoholic fatty liver disease in zebrafish (Q28539163)

2

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Ana M Vacaru

3

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Ravi Sachidanandam

4

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Orkhontuya Tsedensodnom

5

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Taisa Vasilkova

6

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Christoph Buettner

7

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Kirsten C Sadler

Creative Commons Attribution 4.0 International

8

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language of work or name

English

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publication date

2014

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published in

PLOS Genetics

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volume

10

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issue

5

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page(s)

e1004335

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copyright license

start time

29 May 2014

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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describes a project that uses

ImageJ

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4038464/fullTextXML

inferred from PubMed Central ID database lookup

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29 September 2017

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The eIF2 kinase PERK and the integrated stress response facilitate activation of ATF6 during endoplasmic reticulum stress.

29 September 2017

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Alcohol disrupts endoplasmic reticulum function and protein secretion in hepatocytes

29 September 2017

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Sodium phenylbutyrate, a drug with known capacity to reduce endoplasmic reticulum stress, partially alleviates lipid-induced insulin resistance and beta-cell dysfunction in humans

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CYP2E1 enhances ethanol-induced lipid accumulation but impairs autophagy in HepG2 E47 cells

29 September 2017

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29 September 2017

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Tauroursodeoxycholic Acid may improve liver and muscle but not adipose tissue insulin sensitivity in obese men and women.

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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Transcriptional activation of ATF6 by endoplasmic reticulum stressors

29 September 2017

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29 September 2017

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29 September 2017

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Molecular mechanisms of alcoholic fatty liver: role of sterol regulatory element-binding proteins

29 September 2017

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ATF6 modulates SREBP2-mediated lipogenesis.

29 September 2017

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Betaine decreases hyperhomocysteinemia, endoplasmic reticulum stress, and liver injury in alcohol-fed mice

29 September 2017

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29 September 2017

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Activation of cholesterol synthesis in preference to fatty acid synthesis in liver and adipose tissue of transgenic mice overproducing sterol regulatory element-binding protein-2.

29 September 2017

1 reference

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Overproduction of cholesterol and fatty acids causes massive liver enlargement in transgenic mice expressing truncated SREBP-1a

29 September 2017

1 reference

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Endoplasmic reticulum stress is involved in hepatic SREBP-1c activation and lipid accumulation in fructose-fed mice

29 September 2017

1 reference

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The basic helix-loop-helix transcription factor, heart and neural crest derivatives expressed transcript 2, marks hepatic stellate cells in zebrafish: analysis of stellate cell entry into the developing liver

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4038464

Activating transcription factor 6 plays protective and pathological roles in steatosis due to endoplasmic reticulum stress in zebrafish

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4038464

The unfolded protein response transducer IRE1α prevents ER stress-induced hepatic steatosis

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4038464

Endoplasmic reticulum stress inhibition protects steatotic and non-steatotic livers in partial hepatectomy under ischemia-reperfusion

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4038464

Induction of liver steatosis and lipid droplet formation in ATF6alpha-knockout mice burdened with pharmacological endoplasmic reticulum stress

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4038464

Hepatic steatosis in response to acute alcohol exposure in zebrafish requires sterol regulatory element binding protein activation

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4038464

UPR pathways combine to prevent hepatic steatosis caused by ER stress-mediated suppression of transcriptional master regulators.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4038464

Glyceroneogenesis is the dominant pathway for triglyceride glycerol synthesis in vivo in the rat

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4038464

ATF6alpha optimizes long-term endoplasmic reticulum function to protect cells from chronic stress

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4038464

Activation and dysregulation of the unfolded protein response in nonalcoholic fatty liver disease

3 June 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1004335

Chronic ethanol feeding and folate deficiency activate hepatic endoplasmic reticulum stress pathway in micropigs

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1004335

Liver X receptor in cooperation with SREBP-1c is a major lipid synthesis regulator in nonalcoholic fatty liver disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1004335

Fgf10 regulates hepatopancreatic ductal system patterning and differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1004335

ATF4 and the integrated stress response are induced by ethanol and cytochrome P450 2E1 in human hepatocytes

21 January 2018

1 reference

12 December 2020

Endoplasmic reticulum stress causes the activation of sterol regulatory element binding protein-2

1 reference

12 December 2020

Alcoholic liver disease

1 reference

12 December 2020

Saturated fatty acids promote endoplasmic reticulum stress and liver injury in rats with hepatic steatosis

1 reference

12 December 2020

Differential contributions of ATF6 and XBP1 to the activation of endoplasmic reticulum stress-responsive cis-acting elements ERSE, UPRE and ERSE-II

1 reference

12 December 2020

10.1371/JOURNAL.PGEN.1004335

Identifiers

DOI

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

37734

OpenCitations bibliographic resource ID

37734

1 reference