The farnesoid X-receptor is an essential regulator of cholesterol homeostasis (Q28513874)

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14 December 2019

title

The farnesoid X-receptor is an essential regulator of cholesterol homeostasis (English)

2 references

25 January 2017

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Nuclear receptor subfamily 1, group H, member 4

14 December 2019

main subject

1 reference

GOA release 2020-03-11

author

Gilles Lambert

1

1 reference

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14 December 2019

author name string

Grace Guo

3

2 references

25 January 2017

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14 December 2019

Marcelo J A Amar

2

1 reference

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14 December 2019

H Bryan Brewer

4

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14 December 2019

Frank J Gonzalez

5

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14 December 2019

Christopher J Sinal

6

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14 December 2019

language of work or name

English

0 references

publication date

5 November 2002

1 reference

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Journal of Biological Chemistry

14 December 2019

published in

2 references

25 January 2017

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14 December 2019

volume

278

2 references

25 January 2017

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14 December 2019

page(s)

2563-2570

1 reference

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14 December 2019

issue

4

2 references

25 January 2017

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Evolution of the nuclear receptor superfamily: early diversification from an ancestral orphan receptor

14 December 2019

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209525200

Cholesterol and bile acid metabolism are impaired in mice lacking the nuclear oxysterol receptor LXR alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209525200

Identification of a nuclear receptor for bile acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209525200

Bile acids: natural ligands for an orphan nuclear receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209525200

Endogenous bile acids are ligands for the nuclear receptor FXR/BAR

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209525200

The role of orphan nuclear receptors in the regulation of cholesterol homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209525200

Regulation of lipoprotein lipase by the oxysterol receptors, LXRalpha and LXRbeta.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209525200

Sterol upregulation of human CETP expression in vitro and in transgenic mice by an LXR element

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209525200

Sterol-dependent transactivation of the ABC1 promoter by the liver X receptor/retinoid X receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209525200

A PPAR gamma-LXR-ABCA1 pathway in macrophages is involved in cholesterol efflux and atherogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209525200

Accumulation of dietary cholesterol in sitosterolemia caused by mutations in adjacent ABC transporters

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209525200

Targeted disruption of the nuclear receptor FXR/BAR impairs bile acid and lipid homeostasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209525200

Genes involved in initial steps of bile acid synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209525200

ABCA1 overexpression leads to hyperalphalipoproteinemia and increased biliary cholesterol excretion in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209525200

Analysis of glomerulosclerosis and atherosclerosis in lecithin cholesterol acyltransferase-deficient mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209525200

Identification of scavenger receptor SR-BI as a high density lipoprotein receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209525200

Regulation of the mevalonate pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209525200

The role of apolipoprotein A-IV in the regulation of food intake

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209525200

Regulation of ATP-binding cassette sterol transporters ABCG5 and ABCG8 by the liver X receptors alpha and beta.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209525200

Molecular cloning of the promoter for rat hepatic neutral cholesterol ester hydrolase: evidence for transcriptional regulation by sterols

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209525200

Disruption of the sterol carrier protein 2 gene in mice impairs biliary lipid and hepatic cholesterol metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209525200

Biliary cholesterol hypersecretion in gallstone-susceptible mice is associated with hepatic up-regulation of the high-density lipoprotein receptor SRBI.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209525200

Hepatocyte nuclear factor-1alpha is an essential regulator of bile acid and plasma cholesterol metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209525200

Targeted mutation reveals a central role for SR-BI in hepatic selective uptake of high density lipoprotein cholesterol

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209525200

A targeted mutation in the murine gene encoding the high density lipoprotein (HDL) receptor scavenger receptor class B type I reveals its key role in HDL metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209525200

Increased production of apolipoprotein B-containing lipoproteins in the absence of hyperlipidemia in transgenic mice expressing cholesterol 7alpha-hydroxylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209525200

21 January 2018

Bile salt transporters

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209525200

Identification of a bile acid-responsive element in the human ileal bile acid-binding protein gene. Involvement of the farnesoid X receptor/9-cis-retinoic acid receptor heterodimer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209525200

High density lipoprotein deficiency and foam cell accumulation in mice with targeted disruption of ATP-binding cassette transporter-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209525200

ATP-binding cassette transporter A1 (ABCA1) affects total body sterol metabolism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209525200

Targeted inactivation of sister of P-glycoprotein gene (spgp) in mice results in nonprogressive but persistent intrahepatic cholestasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209525200

The nuclear receptor PXR is a lithocholic acid sensor that protects against liver toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209525200

An essential role for nuclear receptors SXR/PXR in detoxification of cholestatic bile acids.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209525200

Regulation of multidrug resistance-associated protein 2 (ABCC2) by the nuclear receptors pregnane X receptor, farnesoid X-activated receptor, and constitutive androstane receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209525200

A natural product that lowers cholesterol as an antagonist ligand for FXR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209525200

The hypolipidemic natural product guggulsterone acts as an antagonist of the bile acid receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209525200

Generation of multiple farnesoid-X-receptor isoforms through the use of alternative promoters

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209525200

21 January 2018

Identifiers

DOI

10.1074/JBC.M209525200

2 references

Consolidated OpenCitations Corpus – April 2017

4118120

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14 December 2019

4118120

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

2 references

4118120