Proteome-wide substrate analysis indicates substrate exclusion as a mechanism to generate caspase-7 versus caspase-3 specificity (Q28513191)

Caspase 3

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Caspase 7

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Poly [ADP-ribose] polymerase 1

1 reference

author

Kris Gevaert

15

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Joël Vandekerckhove

13

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Petra Van Damme

2

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Francis Impens

8

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Kenny Helsens

7

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Peter Vandenabeele

16

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Tom Vanden Berghe

object named as

Tom Vanden Berghe

3

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Joost Schymkowitz

object named as

Joost Schymkowitz

10

0 references

Wim Declercq

14

object named as

Wim Declercq

1 reference

25 January 2017

1

Dieter Demon

1 reference

25 January 2017

5

Joost Van Durme

1 reference

25 January 2017

9

Magdalena Wejda

1 reference

25 January 2017

Annelies Deceuninck

4

1 reference

25 January 2017

Jelle Verspurten

6

1 reference

25 January 2017

Frederic Rousseau

11

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25 January 2017

Annemieke Madder

Molecular & Cellular Proteomics

12

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25 January 2017

1 December 2009

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25 January 2017

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25 January 2017

8

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25 January 2017

12

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25 January 2017

2700–2714

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25 January 2017

Structural basis for executioner caspase recognition of P5 position in substrates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2816020

Global sequencing of proteolytic cleavage sites in apoptosis by specific labeling of protein N termini

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2816020

Differential cleavage of Mst1 by caspase-7/-3 is responsible for TRAIL-induced activation of the MAPK superfamily

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2816020

Plasticity of S2-S4 specificity pockets of executioner caspase-7 revealed by structural and kinetic analysis

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2816020

Proteome-wide Identification of HtrA2/Omi Substrates

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2816020

Structural and kinetic analysis of caspase-3 reveals role for s5 binding site in substrate recognition

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2816020

Caspases 3 and 7: key mediators of mitochondrial events of apoptosis

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2816020

The FoldX web server: an online force field

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2816020

Mechanisms of caspase activation

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2816020

Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2816020

Stable isotope labeling by amino acids in cell culture, SILAC, as a simple and accurate approach to expression proteomics

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2816020

Internally quenched fluorescent peptide substrates disclose the subsite preferences of human caspases 1, 3, 6, 7 and 8

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2816020

The structures of caspases-1, -3, -7 and -8 reveal the basis for substrate and inhibitor selectivity

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2816020

Probability-based protein identification by searching sequence databases using mass spectrometry data

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2816020

Essential contribution of caspase 3/CPP32 to apoptosis and its associated nuclear changes

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2816020

A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2816020

Analysis of protein processing by N-terminal proteomics reveals novel species-specific substrate determinants of granzyme B orthologs

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2816020

Executioner caspase-3 and caspase-7 are functionally distinct proteases

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2816020

Targeted peptidecentric proteomics reveals caspase-7 as a substrate of the caspase-1 inflammasomes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2816020

Proteome-derived, database-searchable peptide libraries for identifying protease cleavage sites

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2816020

Reconstruction of protein backbones from the BriX collection of canonical protein fragments

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2816020

Mechanistic insight into taxol-induced cell death

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2816020

Proteome-wide identification of family member-specific natural substrate repertoire of caspases

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2816020

Proteolytic cleavage of ataxin-7 by caspase-7 modulates cellular toxicity and transcriptional dysregulation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2816020

Controlled peptide solvation in portion-mixing libraries of FRET peptides: improved specificity determination for Dengue 2 virus NS2B-NS3 protease and human cathepsin S.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2816020

Identification of proteolytic cleavage sites by quantitative proteomics

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2816020

The apoptosome: signalling platform of cell death

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2816020

The CASBAH: a searchable database of caspase substrates

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2816020

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2816020

Caspases in cell survival, proliferation and differentiation.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2816020

The protein structures that shape caspase activity, specificity, activation and inhibition

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2816020

Making optimal use of empirical energy functions: force-field parameterization in crystal space

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2816020

Many cuts to ruin: a comprehensive update of caspase substrates

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2816020

The endothelial monocyte-activating polypeptide II (EMAP II) is a substrate for caspase-7.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2816020

Macrophages induce cellular immunity by activating Th1 cell responses and suppressing Th2 cell responses.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2816020

Decreased apoptosis in the brain and premature lethality in CPP32-deficient mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2816020

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2816020

The proteolytic procaspase activation network: an in vitro analysis.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2816020

Caspase-specific and nonspecific in vivo protein processing during Fas-induced apoptosis.

2 June 2018

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M900310-MCP200

Caspase-7 expanded function and intrinsic expression level underlies strain-specific brain phenotype of caspase-3-null mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M900310-MCP200

Isolation of AmphiCASP-3/7, an ancestral caspase from amphioxus (Branchiostoma floridae). Evolutionary considerations for vertebrate caspases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M900310-MCP200

Overlapping cleavage motif selectivity of caspases: implications for analysis of apoptotic pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M900310-MCP200

Improved recovery of proteome-informative, protein N-terminal peptides by combined fractional diagonal chromatography (COFRADIC).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M900310-MCP200

Shotgun proteome analysis of protein cleavage in apoptotic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M900310-MCP200

DBToolkit: processing protein databases for peptide-centric proteomics

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M900310-MCP200

Substrate specificities of caspase family proteases

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19759058