Mechanism of transcriptional activation by the proto-oncogene Twist1 (Q28512117)

25 January 2017

title

Mechanism of transcriptional activation by the proto-oncogene Twist1 (English)

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Twist basic helix-loop-helix transcription factor 1

25 January 2017

main subject

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GOA release 2020-03-11

author name string

Kristian Bruun Laursen

1

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25 January 2017

Esther Mielke

2

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25 January 2017

Philip Iannaccone

3

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25 January 2017

Ernst-Martin Füchtbauer

4

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25 January 2017

language of work or name

English

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publication date

30 November 2007

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Journal of Biological Chemistry

25 January 2017

published in

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25 January 2017

volume

282

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25 January 2017

issue

48

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25 January 2017

page(s)

34623–34633

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Establishment of distinct MyoD, E2A, and twist DNA binding specificities by different basic region-DNA conformations

25 January 2017

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707085200

A new DNA binding and dimerization motif in immunoglobulin enhancer binding, daughterless, MyoD, and myc proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707085200

Interactions between heterologous helix-loop-helix proteins generate complexes that bind specifically to a common DNA sequence

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707085200

Functional activity of myogenic HLH proteins requires hetero-oligomerization with E12/E47-like proteins in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707085200

MyoD binds cooperatively to two sites in a target enhancer sequence: occupancy of two sites is required for activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707085200

The protein Id: a negative regulator of helix-loop-helix DNA binding proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707085200

Muscle-specific transcriptional activation by MyoD

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707085200

Transcriptional activation domain of the muscle-specific gene-regulatory protein myf5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707085200

E2A and E2-2 are subunits of B-cell-specific E2-box DNA-binding proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707085200

Repression of muscle-specific gene activation by the murine Twist protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707085200

Phosphorylation of E47 as a potential determinant of B-cell-specific activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707085200

Dimerization through the helix-loop-helix motif enhances phosphorylation of the transcription activation domains of myogenin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707085200

Acetylation of MyoD directed by PCAF is necessary for the execution of the muscle program

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707085200

The twist gene: isolation of a Drosophila zygotic gene necessary for the establishment of dorsoventral pattern

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707085200

dorsal-twist interactions establish snail expression in the presumptive mesoderm of the Drosophila embryo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707085200

FGF and genes encoding transcription factors in early limb specification

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707085200

The dorsal gradient morphogen regulates stripes of rhomboid expression in the presumptive neuroectoderm of the Drosophila embryo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707085200

Twist-mediated activation of the NK-4 homeobox gene in the visceral mesoderm of Drosophila requires two distinct clusters of E-box regulatory elements.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707085200

The myogenic regulatory gene Mef2 is a direct target for transcriptional activation by Twist during Drosophila myogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707085200

M-twist is an inhibitor of muscle differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707085200

Dermo-1, a multifunctional basic helix-loop-helix protein, represses MyoD transactivation via the HLH domain, MEF2 interaction, and chromatin deacetylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707085200

The basic domain of myogenic basic helix-loop-helix (bHLH) proteins is the novel target for direct inhibition by another bHLH protein, Twist

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707085200

Regulation of histone acetyltransferases p300 and PCAF by the bHLH protein twist and adenoviral oncoprotein E1A

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707085200

Twist regulates cytokine gene expression through a negative feedback loop that represses NF-kappaB activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707085200

Twist is a potential oncogene that inhibits apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707085200

Differential roles of p300 and PCAF acetyltransferases in muscle differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707085200

Molecular mechanisms of myogenic coactivation by p300: direct interaction with the activation domain of MyoD and with the MADS box of MEF2C

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707085200

Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707085200

N-cadherin gene expression in prostate carcinoma is modulated by integrin-dependent nuclear translocation of Twist1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707085200

Cooperative E-box regulation of human GLI1 by TWIST and USF

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707085200

Twist transcriptionally up-regulates AKT2 in breast cancer cells leading to increased migration, invasion, and resistance to paclitaxel

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707085200

Oncogenic cooperation between H-Twist and N-Myc overrides failsafe programs in cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707085200

Twist overexpression induces in vivo angiogenesis and correlates with chromosomal instability in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707085200

Up-regulation of TWIST in prostate cancer and its implication as a therapeutic target

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707085200

Twist, a novel oncogene, is upregulated in pancreatic cancer: clinical implication of Twist expression in pancreatic juice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707085200

Expression of M-twist during postimplantation development of the mouse.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707085200

twist is required in head mesenchyme for cranial neural tube morphogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707085200

Twist function is required for the morphogenesis of the cephalic neural tube and the differentiation of the cranial neural crest cells in the mouse embryo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707085200

Mutations in TWIST, a basic helix-loop-helix transcription factor, in Saethre-Chotzen syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707085200

Mutations of the TWIST gene in the Saethre-Chotzen syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707085200

Common regulation of growth arrest and differentiation of osteoblasts by helix-loop-helix factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707085200

Human Dermo-1 has attributes similar to twist in early bone development

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707085200

A twist code determines the onset of osteoblast differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707085200

TWIST inactivation reduces CBFA1/RUNX2 expression and DNA binding to the osteocalcin promoter in osteoblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707085200

A role for fibroblast growth factor receptor-2 in the altered osteoblast phenotype induced by Twist haploinsufficiency in the Saethre-Chotzen syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707085200

Analysis of a Caenorhabditis elegans Twist homolog identifies conserved and divergent aspects of mesodermal patterning

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707085200

A novel mechanism for the regulation of osteoblast differentiation: transcription of periostin, a member of the fasciclin I family, is regulated by the bHLH transcription factor, twist.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707085200

A Drosophila model to study the functions of TWIST orthologs in apoptosis and proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707085200

Transcription of the muscle regulatory gene Myf4 is regulated by serum components, peptide growth factors and signaling pathways involving G proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707085200

Translation of mRNA injected into Xenopus oocytes is specifically inhibited by antisense RNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707085200

Characterization of a newly derived human sarcoma cell line (HT-1080).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707085200

Serial passaging and differentiation of myogenic cells isolated from dystrophic mouse muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707085200

A chemiluminescent assay for quantitation of β-galactosidase in the femtogram range: Application to quantitation of β-galactosidase in lacZ-transfected cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707085200

Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707085200

HLH forced dimers: tethering MyoD to E47 generates a dominant positive myogenic factor insulated from negative regulation by Id.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707085200

A new transcriptional-activation motif restricted to a class of helix-loop-helix proteins is functionally conserved in both yeast and mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707085200

A splice variant of the ITF-2 transcript encodes a transcription factor that inhibits MyoD activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707085200

The E2A gene product contains two separable and functionally distinct transcription activation domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707085200

Enhancer-specific modulation of E protein activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707085200

A Twist in fate: evolutionary comparison of Twist structure and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707085200

Functional replacement of the mouse E2A gene with a human HEB cDNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707085200

Altered Twist1 and Hand2 dimerization is associated with Saethre-Chotzen syndrome and limb abnormalities

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707085200

Analysis of the inhibition of MyoD activity by ITF-2B and full-length E12/E47.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707085200

Twist is substrate for caspase cleavage and proteasome-mediated degradation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707085200

The AD1 transactivation domain of E2A contains a highly conserved helix which is required for its activity in both Saccharomyces cerevisiae and mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707085200

Significance of TWIST expression and its association with E-cadherin in bladder cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707085200