G-protein-coupled receptor-mediated activation of rap GTPases: characterization of a novel Galphai regulated pathway (Q28510679)

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25 January 2017

Anthony Essex

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25 January 2017

Yan Gao

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25 January 2017

Ethan S. Burstein

Cyclic AMP-dependent activation of Rap1b

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25 January 2017

language of work or name

English

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publication date

8 January 2004

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25 January 2017

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25 January 2017

23

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25 January 2017

241–249

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25 January 2017

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1207014

Mitogenic and oncogenic properties of the small G protein Rap1b

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207014

Rap1 signalling: adhering to new models

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207014

Structure-function of muscarinic receptor coupling to G proteins. Random saturation mutagenesis identifies a critical determinant of receptor affinity for G proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207014

A CalDAG-GEFI/Rap1/B-Raf cassette couples M(1) muscarinic acetylcholine receptors to the activation of ERK1/2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207014

Muscarinic acetylcholine receptor subtypes as agonist-dependent oncogenes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207014

A selective role for phosphatidylinositol 3,4,5-trisphosphate in the Gi-dependent activation of platelet Rap1B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207014

A Gi-dependent pathway is required for activation of the small GTPase Rap1B in human platelets

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207014

Gbetagamma subunits mediate Src-dependent phosphorylation of the epidermal growth factor receptor. A scaffold for G protein-coupled receptor-mediated Ras activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207014

Role of c-Src tyrosine kinase in G protein-coupled receptor- and Gbetagamma subunit-mediated activation of mitogen-activated protein kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207014

The beta(2)-adrenergic receptor mediates extracellular signal-regulated kinase activation via assembly of a multi-receptor complex with the epidermal growth factor receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207014

Activation of the Rap1 GTPase by the B cell antigen receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207014

Activation of brain B-Raf protein kinase by Rap1B small GTP-binding protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207014

The small GTPase, Rap1, mediates CD31-induced integrin adhesion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207014

On the mitogenic properties of Rap1b: cAMP-induced G(1)/S entry requires activated and phosphorylated Rap1b

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207014

beta 2-adrenergic receptor activates extracellular signal-regulated kinases (ERKs) via the small G protein rap1 and the serine/threonine kinase B-Raf

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207014

C3G, a guanine nucleotide-releasing protein expressed ubiquitously, binds to the Src homology 3 domains of CRK and GRB2/ASH proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207014

Analysis of the Gs/mitogen-activated protein kinase pathway in mutant S49 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207014

Activation of Rap1B by G(i) family members in platelets

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207014

Interactions of muscarinic receptors with the heterotrimeric G proteins Gq and G12: transduction of proliferative signals.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207014

7 January 2021

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207014

7 January 2021

Human Sos1: a guanine nucleotide exchange factor for Ras that binds to GRB2

1 reference

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7 January 2021

Dual effect of beta-adrenergic receptors on mitogen-activated protein kinase. Evidence for a beta gamma-dependent activation and a G alpha s-cAMP-mediated inhibition

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207014

7 January 2021

Ras-dependent activation of MAP kinase pathway mediated by G-protein beta gamma subunits.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207014

7 January 2021

Signal characteristics of G protein-transactivated EGF receptor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207014

7 January 2021

Role of transactivation of the EGF receptor in signalling by G-protein-coupled receptors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207014

7 January 2021

Minimal Ras-binding domain of Raf1 can be used as an activation-specific probe for Ras.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207014

7 January 2021

Epac is a Rap1 guanine-nucleotide-exchange factor directly activated by cyclic AMP

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207014

7 January 2021

Rapid Ca2+-mediated activation of Rap1 in human platelets

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207014

7 January 2021

Identification of Rap1 as a target for the Crk SH3 domain-binding guanine nucleotide-releasing factor C3G

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207014

7 January 2021

The cellular functions of small GTP-binding proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207014

7 January 2021

Coassociation of Rap1A and Ha-Ras with Raf-1 N-terminal region interferes with ras-dependent activation of Raf-1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207014

7 January 2021

A family of cAMP-binding proteins that directly activate Rap1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207014

7 January 2021

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207014

7 January 2021

Beta-arrestin-dependent formation of beta2 adrenergic receptor-Src protein kinase complexes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207014

7 January 2021

Cyclic AMP-mediated inhibition of cell growth requires the small G protein Rap1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207014

7 January 2021

Activation of mitogen-activated protein kinase by the A(2A)-adenosine receptor via a rap1-dependent and via a p21(ras)-dependent pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207014

7 January 2021

G protein-coupled receptors and proliferative signaling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207014

7 January 2021

Crosstalk between cAMP and MAP kinase signaling in the regulation of cell proliferation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207014

7 January 2021

Cyclic AMP activates Ras.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207014

7 January 2021

Coordinated regulation of Rap1 and thyroid differentiation by cyclic AMP and protein kinase A.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207014

7 January 2021

Discriminatory residues in Ras and Rap for guanine nucleotide exchange factor recognition

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207014

7 January 2021

cAMP activates MAP kinase and Elk-1 through a B-Raf- and Rap1-dependent pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207014

7 January 2021

c-Src signaling induced by the adapters Sin and Cas is mediated by Rap1 GTPase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207014

7 January 2021

Rap1 mediates sustained MAP kinase activation induced by nerve growth factor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207014

7 January 2021

Identification of small clusters of divergent amino acids that mediate the opposing effects of ras and Krev-1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207014

7 January 2021