Placental but not heart defects are associated with elevated hypoxia-inducible factor alpha levels in mice lacking prolyl hydroxylase domain protein 2 (Q28508549)

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English	Placental but not heart defects are associated with elevated hypoxia-inducible factor alpha levels in mice lacking prolyl hydroxylase domain protein 2	scientific journal article

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scholarly article

1 reference

24 January 2017

Placental but not heart defects are associated with elevated hypoxia-inducible factor alpha levels in mice lacking prolyl hydroxylase domain protein 2 (English)

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24 January 2017

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Egl-9 family hypoxia-inducible factor 1

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GOA release 2020-03-11

object named as

Andras Nagy

5

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author name string

Kotaro Takeda

1

1 reference

24 January 2017

Vivienne C. Ho

2

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24 January 2017

Hiromi Takeda

3

1 reference

24 January 2017

Li-Juan Duan

4

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24 January 2017

Guo-Hua Fong

6

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24 January 2017

language of work or name

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publication date

1 November 2006

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24 January 2017

Molecular and Cellular Biology

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24 January 2017

26

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24 January 2017

8336–8346

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24 January 2017

22

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24 January 2017

Loss of Cited2 affects trophoblast formation and vascularization of the mouse placenta

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636770

19 March 2017

A family with erythrocytosis establishes a role for prolyl hydroxylase domain protein 2 in oxygen homeostasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636770

19 March 2017

Phospholipase C-delta1 and -delta3 are essential in the trophoblast for placental development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636770

19 March 2017

Hypoxia-inducible factors 1alpha and 2alpha regulate trophoblast differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636770

19 March 2017

Suppression of hypoxia-inducible factor 1alpha (HIF-1alpha) transcriptional activity by the HIF prolyl hydroxylase EGLN1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636770

19 March 2017

The candidate tumor suppressor ING4 represses activation of the hypoxia inducible factor (HIF).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636770

19 March 2017

Differential function of the prolyl hydroxylases PHD1, PHD2, and PHD3 in the regulation of hypoxia-inducible factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636770

19 March 2017

HIF prolyl-hydroxylase 2 is the key oxygen sensor setting low steady-state levels of HIF-1alpha in normoxia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636770

19 March 2017

Hypoxia up-regulates prolyl hydroxylase activity: a feedback mechanism that limits HIF-1 responses during reoxygenation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636770

19 March 2017

Characterization of the human prolyl 4-hydroxylases that modify the hypoxia-inducible factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636770

19 March 2017

Intracellular localisation of human HIF-1 alpha hydroxylases: implications for oxygen sensing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636770

19 March 2017

A conserved family of prolyl-4-hydroxylases that modify HIF

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636770

19 March 2017

C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636770

19 March 2017

Placental defects and embryonic lethality in mice lacking suppressor of cytokine signaling 3

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636770

19 March 2017

HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636770

19 March 2017

Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636770

19 March 2017

The transcription factor EPAS-1/hypoxia-inducible factor 2alpha plays an important role in vascular remodeling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636770

19 March 2017

The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636770

19 March 2017

The hypoxia-responsive transcription factor EPAS1 is essential for catecholamine homeostasis and protection against heart failure during embryonic development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636770

19 March 2017

HIF-1 alpha is required for solid tumor formation and embryonic vascularization.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636770

19 March 2017

Cellular and developmental control of O2 homeostasis by hypoxia-inducible factor 1 alpha

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636770

19 March 2017

Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636770

19 March 2017

Transcriptional regulation of genes encoding glycolytic enzymes by hypoxia-inducible factor 1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636770

19 March 2017

Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636770

19 March 2017

Efficient in vivo manipulation of mouse genomic sequences at the zygote stage

1 reference

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7 April 2017

Derivation of completely cell culture-derived mice from early-passage embryonic stem cells

1 reference

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7 April 2017

A highly efficient recombineering-based method for generating conditional knockout mutations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636770

7 April 2017

Placental development: lessons from mouse mutants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636770

7 April 2017

Detection of messenger RNA by in situ hybridization to tissue sections and whole mounts

1 reference

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7 April 2017

HIF prolyl and asparaginyl hydroxylases in the biological response to intracellular O(2) levels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636770

29 September 2017

Determination of hypoxic region by hypoxia marker in developing mouse embryos in vivo: a possible signal for vessel development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636770

29 September 2017

Placental cell fates are regulated in vivo by HIF-mediated hypoxia responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636770

29 September 2017

Induction of endothelial PAS domain protein-1 by hypoxia: characterization and comparison with hypoxia-inducible factor-1alpha

1 reference

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29 September 2017

Defective placental vasculogenesis causes embryonic lethality in VHL-deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636770

29 September 2017

Hypoxia-inducible nuclear factors bind to an enhancer element located 3' to the human erythropoietin gene

1 reference

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Mammalian EGLN genes have distinct patterns of mRNA expression and regulation

1 reference

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Abnormal angiogenesis and responses to glucose and oxygen deprivation in mice lacking the protein ARNT.

1 reference

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27 November 2018

Hypoxia-inducible factor 1: master regulator of O2 homeostasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16966370

12 December 2020

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