Initial characterization of the glutamate-cysteine ligase modifier subunit Gclm(-/-) knockout mouse. Novel model system for a severely compromised oxidative stress response (Q28507715)

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English	Initial characterization of the glutamate-cysteine ligase modifier subunit Gclm(-/-) knockout mouse. Novel model system for a severely compromised oxidative stress response	scientific journal article

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scholarly article

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24 January 2017

Initial characterization of the glutamate-cysteine ligase modifier subunit Gclm(-/-) knockout mouse. Novel model system for a severely compromised oxidative stress response (English)

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24 January 2017

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Glutamate-cysteine ligase, catalytic subunit

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GOA release 2020-03-11

Glutamate-cysteine ligase, modifier subunit

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GOA release 2020-03-11

oxidative stress

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author name string

Yi Yang

1

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24 January 2017

Matthew Z. Dieter

2

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24 January 2017

Ying Chen

3

1 reference

24 January 2017

Howard G. Shertzer

4

1 reference

24 January 2017

Daniel W. Nebert

5

1 reference

24 January 2017

Timothy P. Dalton

6

1 reference

24 January 2017

language of work or name

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publication date

20 December 2002

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24 January 2017

Journal of Biological Chemistry

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24 January 2017

277

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24 January 2017

49446–49452

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24 January 2017

51

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24 January 2017

1 reference

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21 January 2018

Recent trends in glutathione biochemistry--glutathione-protein interactions: a molecular link between oxidative stress and cell proliferation?

1 reference

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Role of the liver in interorgan homeostasis of glutathione and cyst(e)ine

1 reference

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Antioxidant function of thioredoxin and glutaredoxin systems

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Glutathione and its role in cellular functions

1 reference

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Novel roles for glutathione in gene expression, cell death, and membrane transport of organic solutes

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https://api.crossref.org/works/10.1074%2FJBC.M209372200

21 January 2018

Glutathione metabolism.

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21 January 2018

Glutathione synthesis is essential for mouse development but not for cell growth in culture

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21 January 2018

Knockout of the mouse glutamate cysteine ligase catalytic subunit (Gclc) gene: embryonic lethal when homozygous, and proposed model for moderate glutathione deficiency when heterozygous

1 reference

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21 January 2018

Expression and purification of human gamma-glutamylcysteine synthetase

1 reference

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21 January 2018

Overexpression of the regulatory subunit of gamma-glutamylcysteine synthetase in HeLa cells increases gamma-glutamylcysteine synthetase activity and confers drug resistance

1 reference

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21 January 2018

Hammerhead ribozymes against gamma-glutamylcysteine synthetase mRNA down-regulate intracellular glutathione concentration of mouse islet cells

1 reference

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21 January 2018

Multi-faceted regulation of gamma-glutamylcysteine synthetase

1 reference

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21 January 2018

Glutamate-cysteine ligase modifier subunit: mouse Gclm gene structure and regulation by agents that cause oxidative stress

1 reference

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Determining glutathione and glutathione disulfide using the fluorescence probe o-phthalaldehyde

1 reference

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Enzyme induction by L-buthionine (S,R)-sulfoximine in cultured mouse hepatoma cells.

1 reference

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Growth retardation and cysteine deficiency in gamma-glutamyl transpeptidase-deficient mice

1 reference

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21 January 2018

Drosophila melanogaster glutamate-cysteine ligase activity is regulated by a modifier subunit with a mechanism of action similar to that of the mammalian form

1 reference

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21 January 2018

Chemical depletion of glutathione in vivo

1 reference

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21 January 2018

Glutathione deficiency produced by inhibition of its synthesis, and its reversal; Applications in research and therapy

1 reference

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21 January 2018

Cloning and sequencing of the cDNA for the light subunit of human liver gamma-glutamylcysteine synthetase and relative mRNA levels for heavy and light subunits in human normal tissues

1 reference

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21 January 2018

Molecular mechanism of decreased glutathione content in human immunodeficiency virus type 1 Tat-transgenic mice

1 reference

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21 January 2018

Polymorphism in the 5'-flanking region of human glutamate-cysteine ligase modifier subunit gene is associated with myocardial infarction

1 reference

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21 January 2018

Changes in cellular glutathione content during adriamycin treatment in human ovarian cancer--a possible indicator of chemosensitivity

1 reference

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21 January 2018

Glutathione: a vital lens antioxidant

1 reference

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21 January 2018

Effect of inhibition of glutathione synthesis on insulin action: in vivo and in vitro studies using buthionine sulfoximine

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21 January 2018

Identifiers

10.1074/JBC.M209372200

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

OpenCitations bibliographic resource ID

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Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

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